Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.
Cell Phone-basedOptometry Solution  The Inverse of Shack-Hartmann Vitor Pamplona   eyenetra.com
Andres Rueda
Thermometer for vision  Collaboration with: Ankit Mohan , Manuel M. Oliveira, Ramesh Raskar
Thermometer for vision  Collaboration with: Ankit Mohan , Manuel M. Oliveira, Ramesh Raskar
2B have              refractive errors                           0.6B have4.5B have a                   URE cell phone    ...
Shack-Hartmann Wavefront Sensor   Wavefront aberrometerExpensive; Bulky, Requires trained professionals                   ...
Shack-Hartmann Wavefront Sensor                       LaserSpot Diagram                             Planar         Sensor ...
Shack-Hartmann Wavefront Sensor                       Laser    Spot Diagram              SensorDisplacement =   Local Slop...
NETRA = Inverse of Shack-HartmannSpot Diagram on LCD              Cell      Eye             Phone     Piece             Di...
Inverse of Shack-Hartmann       User interactively creates the Spot DiagramSpot Diagram on LCDDisplace 25points but3 param...
Inverse of Shack-Hartmann       User interactively creates the Spot DiagramSpot Diagram on LCDDisplace 25points but3 param...
Relaxed Eye with Myopia                                                  EyeRed point                                     ...
Relaxed Eye with Myopia                                                    Eye                                         Pin...
Relaxed Eye with Myopia                                               Eye                                     Display     ...
Relaxed Eye with Myopia                                               Eye                                     Display Move...
Relaxed Eye with Myopia                                               Eye                                     Display Move...
Relaxed Eye with Myopia                                                   Eye                                        Displ...
Relaxed Eye with Myopia                                                    Eye                                            ...
Interactive Method                     20
Interactive Method                     21
Interactive Method                     22
Interactive Method                     23
Interactive Method      Farthest Focal Point   (myopia, hyperopia, astigmatism)   24
Limitations• Children• Ability to align lines• Resolution is a function of the display DPI   – Samsung Behold II – 160 DPI...
Why Now?   0.35um
NETRA Prototypes Worldwide       29 partners in 14 countries.                   Confidential       27
Clinical Testing Partners
NETRA Team at LVPEI, India
Kenya
Validation: Side by Side Trials                            13 adults                                             29 adults...
Preventable Blindness                  WHO 2004
CATRA: Quantitative                                                Cataract Maps                                          ...
Testing the Presence of CataractsBlinking patterns on Screen                                   Pinhole                    ...
36 years old female with Posterior Sub-Capsular (10%)     Retro-illumination              Slit-lamp      CATRA’s Opacity Map
For the Future• Ophthalmology for Masses   – >.5 billion URE. > 2.5 billion RE. -> Devices for all• Quality of phones (res...
NETRA  Vitor Pamplonahttp://eyenetra.com
Photography in 1960s                       Illana Tamir Roboppy
Today, cameras are everywhere                           Photo: Tyler  Photo: Derek K. Miller                              ...
Optometry TodayWavefront Aberrometer         Corneal Topographer                                                     Phoro...
“point-and-shoot” optometry
Traditional         User DrivenMass-use Devices   Scientific Instruments
Reading Charts• Accuracy   – Sharpness Estimation is subjective   – Brightness affects results   – Pupil size variation an...
New EcosystemMedical IT Systems                         EHR                         Eyecare    Diagnostic                 ...
Needs expert,                   Moving parts,          Shining lasers                          Retino          Auto-      ...
Human Eye                            Retina                            Human EyeCornea(~40D)   Crystalline lens           ...
Human Eye           Accommodation    Retina                            Human EyeCornea(~40D)   Crystalline lens           ...
Perfect Vision System            Infinity                                                    Subject                      ...
Myopia (nearsightedness)            Infinity                                                          Subject             ...
Myopia Correction            Infinity                                                      Subject                        ...
Hyperopia (farsightedness)            Infinity                                                     Wrong                  ...
Hyperopia Correction            Infinity                                       Convergent Lens                            ...
Refractive Errors and Shifted Range   Need to         Perfect vision   measure                               Myopia       ...
Refractive Errors and Shifted Range                           Perfect vision                                        Myopia...
Astigmatism: angle-dependent refractive error                    http://www.elizabethpope.co.uk/eyeinfo/astigmatism.html  ...
Astigmatism: angle-dependent refractive error                    http://www.elizabethpope.co.uk/eyeinfo/astigmatism.html  ...
Astigmatism: angle-dependent refractive error                    http://www.elizabethpope.co.uk/eyeinfo/astigmatism.html  ...
Refractive Power as a       Function of Angle                       2  P(             C sin (           )    SUnknowns:   ...
AstigmatismCross or points may never meet with a 1d search !                                               60
AstigmatismLines reduce the problem to a 1d search   61
Measuring the Accommodation Range                        Perfect vision                                 Myopia            ...
Measuring the Accommodation Range                        Perfect vision                                 Myopia            ...
Measuring the Accommodation Range                        Perfect vision                                 Myopia            ...
Relaxed Eye                   Display                    AVirtual Point at                       Points the far limit     ...
Accommodated Eye                      DisplayMove points towards    each other                       A                    ...
Accommodated Eye                      DisplayMove points towards    each other                       A                    ...
Accommodated Eye                      DisplayMove points towards    each other                       A                    ...
Patterns for Alignment Task               A    B    A    B      A    B       A   B   A   B DisplayedSubject view          ...
Patterns for Alignment Task               A    B    A    B      A    B       A   B   A   B DisplayedSubject view          ...
Summary of Interaction                                   Accommodation Range              Farthest Point                  ...
Upcoming SlideShare
Loading in …5
×

Netra at Mobile Health Expo NYC

1,745 views

Published on

http://eyenetra.com

Published in: Health & Medicine
  • Be the first to comment

Netra at Mobile Health Expo NYC

  1. 1. Cell Phone-basedOptometry Solution The Inverse of Shack-Hartmann Vitor Pamplona eyenetra.com
  2. 2. Andres Rueda
  3. 3. Thermometer for vision Collaboration with: Ankit Mohan , Manuel M. Oliveira, Ramesh Raskar
  4. 4. Thermometer for vision Collaboration with: Ankit Mohan , Manuel M. Oliveira, Ramesh Raskar
  5. 5. 2B have refractive errors 0.6B have4.5B have a URE cell phone 6.5 Billion people
  6. 6. Shack-Hartmann Wavefront Sensor Wavefront aberrometerExpensive; Bulky, Requires trained professionals 6
  7. 7. Shack-Hartmann Wavefront Sensor LaserSpot Diagram Planar Sensor Microlens Wavefront Array
  8. 8. Shack-Hartmann Wavefront Sensor Laser Spot Diagram SensorDisplacement = Local Slopeof the Wavefront 8
  9. 9. NETRA = Inverse of Shack-HartmannSpot Diagram on LCD Cell Eye Phone Piece Display 9
  10. 10. Inverse of Shack-Hartmann User interactively creates the Spot DiagramSpot Diagram on LCDDisplace 25points but3 parameters 10
  11. 11. Inverse of Shack-Hartmann User interactively creates the Spot DiagramSpot Diagram on LCDDisplace 25points but3 parameters 11
  12. 12. Relaxed Eye with Myopia EyeRed point Blurredat infinity point Focusing Range perfect vision myopia hyperopiainfinity ~10cm 12
  13. 13. Relaxed Eye with Myopia Eye PinholesRed point Distinctat infinity image points Focusing Range perfect vision myopia Scheiner’s Principle hyperopia infinity ~10cm 13
  14. 14. Relaxed Eye with Myopia Eye Display AVirtual red point Distinct at infinity image B points Focusing Range perfect vision myopia hyperopia infinity ~10cm 14
  15. 15. Relaxed Eye with Myopia Eye Display Move spotstowards each other A Distinct imageVirtual red point B pointsat finite distance Focusing Range perfect vision myopia hyperopia infinity ~10cm 15
  16. 16. Relaxed Eye with Myopia Eye Display Move spotstowards each other A Points overlapVirtual red point Bat finite distance Focusing Range perfect vision myopia hyperopia infinity ~10cm 16
  17. 17. Relaxed Eye with Myopia Eye Display Move spotstowards each other A Points overlapVirtual red point Bat finite distance d Focusing Range perfect vision myopia hyperopia infinity ~10cm 17
  18. 18. Relaxed Eye with Myopia Eye 1 dPoint at Pointsinfinity overlap d Focusing Range perfect vision myopia hyperopia infinity ~10cm 18
  19. 19. Interactive Method 20
  20. 20. Interactive Method 21
  21. 21. Interactive Method 22
  22. 22. Interactive Method 23
  23. 23. Interactive Method Farthest Focal Point (myopia, hyperopia, astigmatism) 24
  24. 24. Limitations• Children• Ability to align lines• Resolution is a function of the display DPI – Samsung Behold II – 160 DPI – 0.35D – Google Nexus One – 250 DPI – 0.2D – Apple iPhone 4G – 326 DPI – 0.14D 25
  25. 25. Why Now? 0.35um
  26. 26. NETRA Prototypes Worldwide 29 partners in 14 countries. Confidential 27
  27. 27. Clinical Testing Partners
  28. 28. NETRA Team at LVPEI, India
  29. 29. Kenya
  30. 30. Validation: Side by Side Trials 13 adults 29 adults 5.00 7.00 4.00 5.00 3.00 2.00 3.00 1.00 1.00Netra (D) Netra (D) 0.00 -5.00 -3.00 -1.00 1.00 3.00 5.00 -7.00 -1.00 -2.00 3.00 -1.00 -2.00 -3.00 -3.00 -5.00 -4.00 -5.00 -7.00 Retinoscopy (D) Retinoscopy (D) Tufts U. (Boston) LVPEI (India)NETRA vs Manifest Refraction NETRA vs Retinoscopy
  31. 31. Preventable Blindness WHO 2004
  32. 32. CATRA: Quantitative Cataract Maps Unique, quantitative lens mappingwith: Erick Passos, Jan Zizka, Everett Lawson, Esteban Clua , Manuel M. Oliveira, Ramesh Raskar
  33. 33. Testing the Presence of CataractsBlinking patterns on Screen Pinhole Lens Cell Phone Display 34
  34. 34. 36 years old female with Posterior Sub-Capsular (10%) Retro-illumination Slit-lamp CATRA’s Opacity Map
  35. 35. For the Future• Ophthalmology for Masses – >.5 billion URE. > 2.5 billion RE. -> Devices for all• Quality of phones (resolution) will increase exponentially• New features (recently cataracts, next Retinal NETRA)• Smart phones will take over the market in developing world countries like India in next 5 years.• Hardware store
  36. 36. NETRA Vitor Pamplonahttp://eyenetra.com
  37. 37. Photography in 1960s Illana Tamir Roboppy
  38. 38. Today, cameras are everywhere Photo: Tyler Photo: Derek K. Miller Photo: John Kannenberg
  39. 39. Optometry TodayWavefront Aberrometer Corneal Topographer Phoropter Trial set of lenses Lasers Snellen chart
  40. 40. “point-and-shoot” optometry
  41. 41. Traditional User DrivenMass-use Devices Scientific Instruments
  42. 42. Reading Charts• Accuracy – Sharpness Estimation is subjective – Brightness affects results – Pupil size variation and DoF• Cost – Trial Lens Set > $150 – Bulky Snellen chart Phoropter Trial lenses
  43. 43. New EcosystemMedical IT Systems EHR Eyecare Diagnostic Delivery Providers Asynchronous
  44. 44. Needs expert, Moving parts, Shining lasers Retino Auto- Chart In-Focus: Solo- scope w/ refracto- with Focometer Optiopia health: NETRA Lenses meter Lenses EyeSiteTechnology Shining Light Fundus Moving lenses Moving Reading Cellphone plus lenses Camera + target lenses + chart on + eyepiece target monitorCost to buy $2,000* ~$10,000 ~$100 ~$495 ~$200 -- $30Cost per test ~$36 ~$36 ~$5 -- -- -- ~$1Data capture No Comp. No No No Comp. PhoneMobility <500g >10Kg 2kg 1kg <5kg >10Kg <100gSpeed Fast Fast Medium Medium -- Fast FastScalability No No No Yes Probably No YesAccuracy 0.15 0.15 0.5 0.75 -- -- <0.5Self evaluation No No Yes Yes Yes Yes YesElectricity Req No Yes No No -- Yes NoAstigmatism Yes Yes Yes/No No -- Yes YesNetwork No Yes No No No Yes YesTraining High High High Medium Medium Low Low* Phoropter-based: $5,000.00
  45. 45. Human Eye Retina Human EyeCornea(~40D) Crystalline lens (10~20D) 46
  46. 46. Human Eye Accommodation Retina Human EyeCornea(~40D) Crystalline lens (10~20D) 47
  47. 47. Perfect Vision System Infinity Subject can focus at infinity Human EyeAccommodation Range Normal VisionInfinity 10cm 48
  48. 48. Myopia (nearsightedness) Infinity Subject cannot focus Wrong at far focal point distances Human EyeAccommodation Range Normal Vision MyopiaInfinity 10cm 49
  49. 49. Myopia Correction Infinity Subject can focus at infinity Divergent Lens Human EyeAccommodation Range Normal Vision Corrected Myopia MyopiaInfinity 10cm 50
  50. 50. Hyperopia (farsightedness) Infinity Wrong focal point Human EyeAccommodation Range Normal Vision Myopia HyperopiaInfinity 10cm 51
  51. 51. Hyperopia Correction Infinity Convergent Lens Human EyeAccommodation Range Normal Vision Myopia Corrected Hyperopia HyperopiaInfinity 10cm 52
  52. 52. Refractive Errors and Shifted Range Need to Perfect vision measure Myopia Hyperopia Infinity 1m 33cm 10cm Distance 54
  53. 53. Refractive Errors and Shifted Range Perfect vision Myopia Hyperopia Infinity 1m 33cm 10cm Distance+3D +1D 0D -1D -3D -10D Diopter Diopter = 1/Distance 55
  54. 54. Astigmatism: angle-dependent refractive error http://www.elizabethpope.co.uk/eyeinfo/astigmatism.html 56
  55. 55. Astigmatism: angle-dependent refractive error http://www.elizabethpope.co.uk/eyeinfo/astigmatism.html 57
  56. 56. Astigmatism: angle-dependent refractive error http://www.elizabethpope.co.uk/eyeinfo/astigmatism.html 58
  57. 57. Refractive Power as a Function of Angle 2 P( C sin ( ) SUnknowns: Cylinder Axis Cyl. Sphere 59
  58. 58. AstigmatismCross or points may never meet with a 1d search ! 60
  59. 59. AstigmatismLines reduce the problem to a 1d search 61
  60. 60. Measuring the Accommodation Range Perfect vision Myopia Hyperopia Infinity ~10cm Step 1: Far limit Step 2: Near limit 62
  61. 61. Measuring the Accommodation Range Perfect vision Myopia Hyperopia Infinity ~10cm Step 1: Far limit Step 2: Near limit 63
  62. 62. Measuring the Accommodation Range Perfect vision Myopia Hyperopia Infinity ~10cm Step 1: Far limit Step 2: Near limit 64
  63. 63. Relaxed Eye Display AVirtual Point at Points the far limit B overlap 65
  64. 64. Accommodated Eye DisplayMove points towards each other A Points B overlap Virtual point getting closer Subject Accommodates to fix the “blur” 66
  65. 65. Accommodated Eye DisplayMove points towards each other A Points B overlap Virtual point getting closer Subject Accommodates to fix the “blur” 67
  66. 66. Accommodated Eye DisplayMove points towards each other A Points B overlap Virtual point getting closer Subject cannot accommodate more than the previous point 68
  67. 67. Patterns for Alignment Task A B A B A B A B A B DisplayedSubject view A B A B A B A B A B DisplayedSubject view Visual 69 Cryptography [NaorShamir94]
  68. 68. Patterns for Alignment Task A B A B A B A B A B DisplayedSubject view A B A B A B A B A B DisplayedSubject view Visual 70 Cryptography [NaorShamir94]
  69. 69. Summary of Interaction Accommodation Range Farthest Point Nearest Point(myopia, hyperopia, astigmatism) (presbyopia) 71

×