AI in Practice for Healthcare Real or Not NHG final (1).pptx

Vaikunthan Rajaratnam
Vaikunthan RajaratnamSenior Consultant Hand and Reconstructive Microsurgery at Khoo Teck Puat Hospital
Artificial Intelligence in My practice!
Real or Not?
Vaikunthan Rajaratnam
Senior Consultant Hand Surgeon, KTPH, Singapore,
Adjunct Professor & UNESCO Chair Partner,
Asia Pacific University of Technology and Innovation, Malaysia.
28 September 2023
Disclaimer
I am not an AI expert, nor do I
possess coding knowledge
specific to the underlying
mechanisms of AI models; my
expertise lies in the utilisation
of these models, such as
ChatGPT, based on my
extensive experience as a user
within the fields of healthcare,
medical education, and related
research, rather than their
technical development or
underlying algorithms.
AI for Academic Writing Workshop
Write your paper in a day!
8 July 2023
Asia Pacific University of Technology & Innovation (APU)
Malaysia
AI for Learning Design
26 August 2023
Asia Pacific University of Technology & Innovation (APU)
AI in Healthcare: Unleashing the Power in a
One-Day Workshop
Empowering Healthcare Professionals to
Leverage AI in Practice
7 September 2023
Sengkang General
Hospital
Introduction to AI in
Healthcare:
Opportunities and
Challenges
AI technologies have the potential
to revolutionize healthcare by
enhancing diagnosis, treatment
planning, and research.
Understanding AI, Generative AI, and ChatGPT
• AI (Artificial Intelligence)
• refers to the simulation of human intelligence in
machines that are programmed to think, learn, and
make decisions
• Applications: Includes machine learning, natural
language processing, robotics, computer vision, etc.
• Generative AI
• subset of AI that focuses on creating new data
instances that are similar to a set of training
examples.
• Techniques: Examples include Generative Adversarial
Networks (GANs), Variational Autoencoders (VAEs),
etc.
• ChatGPT (Generative Pretrained Transformer):
• State-of-the-art language models developed by
OpenAI. It utilises the Transformer architecture to
generate human-like text based on given prompts.
• Usage: Widely used in natural language understanding
tasks, chatbots, content creation, and more.
Suero-Abreu, G. A., Hamid, A., Akbilgic, O., &
Brown, S.-A. (2022). Trends in cardiology and
oncology artificial intelligence publications.
American Heart Journal Plus: Cardiology
Research and Practice, 17, 100162.
https://doi.org/10.1016/j.ahjo.2022.100162
• Rapid multi-disciplinary
stream of authors
researching AI in Medicine
• Skills and data quality
awareness for data-
intensive analysis
• Limitations
• Ethics,
• Data governance, and
• Competencies of the health
workforce.
• Focuses on
• Health services
management
• Predictive medicine
• Patient data and diagnostics
• Clinical decision-making
Secinaro, S., Calandra, D., Secinaro, A., Muthurangu, V., & Biancone, P. (2021). The role of artificial intelligence in healthcare: A structured
literature review. BMC Medical Informatics and Decision Making, 21(1), 125. https://doi.org/10.1186/s12911-021-01488-9
Health
services
managemen
t
• Optimization of Operational Efficiency
• Example: Scheduling algorithms to optimize staff shifts and patient appointments, reducing wait times.
• Predictive Analytics for Resource Allocation
• Example: Predicting hospital bed occupancy based on patient flow and admission trends for better
resource planning.
• Supply Chain Optimization
• Example: Forecasting the need for medical supplies and automating procurement to reduce inventory
costs.
• Fraud Detection and Compliance
• Example: Detecting fraudulent billing activities and ensuring compliance with healthcare regulations.
• Integration of Care across Providers
• Example: Facilitating seamless information sharing among healthcare providers for coordinated care.
• Enhancing Administrative Decision-Making
• Example: Utilizing data analytics to inform strategic decisions, such as facility expansion or service
prioritization.
• Patient Engagement and Communication
• Example: AI-powered chatbots to handle routine inquiries, appointment scheduling, and patient follow-
ups.
• Workforce Development and Training
• Example: Using AI to identify training needs and deliver personalized learning paths for healthcare staff.
• Performance Monitoring and Quality Assurance
• Example: Implementing AI-driven analytics to monitor performance metrics, identify areas for
improvement, and ensure quality standards.
• Cost Control and Optimization
• Example: Applying AI to analyze cost drivers, identify inefficiencies, and recommend cost-saving
measures.
Predictiv
e
medicine
• Early Disease Detection
• Example: Using AI algorithms to analyze medical imaging for early detection of
cancers, even before symptoms appear.
• Risk Stratification
• Example: Identifying patients at high risk of chronic conditions like heart disease
based on a combination of genetic, lifestyle, and clinical data.
• Personalized Treatment Plans
• Example: Creating tailored treatment regimens by predicting individual responses
to specific drugs or therapies.
• Epidemic Outbreak Prediction
• Example: Analyzing social media, travel patterns, and other data sources to
predict the spread of infectious diseases like flu or COVID-19.
• Hospital Readmission Prediction
• Example: Determining the likelihood of a patient's readmission to the hospital,
allowing for targeted interventions to reduce readmissions.
• Drug Response Prediction
• Example: Predicting how individual patients will respond to certain medications,
minimizing adverse effects, and improving treatment efficacy.
• Genomic Medicine and Genetic Risk Prediction
• Example: Analyzing genetic data to predict susceptibility to genetic disorders and
guide preventive measures.
• Mental Health Outcome Prediction
• Example: Utilizing AI to predict mental health crises or progression of conditions
like depression based on patient behavior and medical history.
• Chronic Disease Management
• Example: Continuous monitoring and prediction of disease progression in chronic
conditions like diabetes, allowing for timely interventions.
Patient data
and
diagnostics
• Automated Data Analysis and Interpretation
• Example: Using AI to analyze complex laboratory results, such as genetic sequencing, to identify patterns and
anomalies.
• Real-Time Monitoring and Alerting
• Example: Continuously tracking vital signs and alerting medical staff to potential issues, such as deterioration in a
patient's condition.
• Enhanced Medical Imaging Interpretation
• Example: Applying AI algorithms to interpret radiological images, such as X-rays and MRIs, with increased accuracy
and speed.
• Predictive Analytics for Personalized Care
• Example: Analyzing patient data to predict individual responses to treatments, enabling more personalized and
effective care plans.
• Data Integration and Holistic Patient Views
• Example: Aggregating data from various sources (e.g., EMRs, wearables) to provide a comprehensive view of a
patient's health status.
• Telemedicine and Remote Diagnostics
• Example: Utilizing AI-powered tools to diagnose and manage patients in remote locations, increasing healthcare
accessibility.
• Natural Language Processing for Clinical Notes
• Example: Extracting valuable information from unstructured clinical notes through AI, enhancing data usability.
• Genomic and Precision Medicine
• Example: Integrating genomic data with clinical information to provide precise diagnoses and personalized treatment
recommendations.
• Chronic Condition Management and Monitoring
• Example: Using AI to diagnose and monitor chronic conditions, such as diabetes, through continuous data analysis.
• Ethical and Security Considerations in Data Handling
• Example: Implementing AI-driven security protocols to ensure patient data privacy and compliance with
regulations.
Clinical
decision-
making
• Evidence-Based Recommendations
• Example: AI systems can analyze vast medical literature to
provide evidence-based treatment recommendations tailored to
individual patient profiles.
• Diagnostic Support Tools
• Example: AI algorithms can assist physicians in diagnosing
complex conditions by analyzing clinical data, medical imaging,
and laboratory results.
• Predicting Patient Outcomes
• Example: Using AI to predict patient responses to various
treatments, aiding in selecting the most effective therapy.
• Treatment Pathway Optimization
• Example: AI can suggest optimal treatment pathways based on
patient characteristics, medical history, and current clinical
guidelines.
• Enhancing Multidisciplinary Collaboration
• Example: AI-driven platforms can facilitate collaboration among
specialists, integrating insights from various disciplines for
comprehensive care.
• Ethical Considerations in Decision Making
• Example: Implementing AI algorithms that consider ethical
principles, such as fairness and transparency, in clinical
Challenges
• Data
• Trust
• Ethics
• Readiness for change,
• Expertise
• Buy-in
• Regulatory strategy
• Scalability
• Evaluation
Golhar, S. P., & Kekapure, S. S. (2022). Artificial Intelligence in Healthcare—A Review. International Journal of Scientific
Research in Science and Technology, 9(4), 381–387. https://doi.org/10.32628/IJSRST229454
Governance
Model for AI
S. Reddy, S. Allan, S. Coghlan, and P. Cooper, ‘A governance model for the application of AI in health care’, J. Am. Med. Inform. Assoc., vol. 27, no.
3, pp. 491–497, Mar. 2020, doi: 10.1093/jamia/ocz192
Rahman, N., Thamotharampillai, T., & Rajaratnam, V. (2023). Ethics, guidelines, and policy for technology in healthcare. In
Medical Equipment Engineering: Design, Manufacture and Applications (pp. 119–147). IET Digital Library.
https://doi.org/10.1049/PBHE054E_ch9
Higgins, D., & Madai, V. I. (2020). From Bit to
Bedside: A Practical Framework for Artificial
Intelligence Product Development in
Healthcare. Advanced Intelligent Systems,
2(10), 2000052.
https://doi.org/10.1002/aisy.202000052
What is ChatGPT?
• Understanding Language
• Reads and comprehends human-written text.
• Generating Text
• Writes human-like text, from answers to creative content.
• Conversation
• Capable of engaging in text-based conversations with users.
• Applications
• Used in virtual assistants, education, content creation, and more.
• Not a Human
• Generates text through algorithms, without feelings or
consciousness.
AI for Clinical Decision-Making and Patient Care
How Does
ChatGPT Work?
“Don’t cry ………..”
“ Don’t cry over….”
• Reading Text:
• Takes in words, questions, or sentences as input.
• Understands the language like a human reading a book.
• Processing Information:
• Breaks down the input into smaller parts to understand the meaning.
• Uses a complex mathematical model to analyse the text.
• Generating Response:
• Constructs a response based on what it has "learned" from reading lots of text.
• Tries to make the response sound like something a human would say.
• No Personal Knowledge or Opinions:
• Doesn't have thoughts, feelings, or personal experiences.
• Answers are based on patterns in the data it was trained on, not personal beliefs
opinions.
• Learning from Data:
• Trained on a vast amount of text from books, websites, and other written materia
• Learns the structure of language and how to create sentences that make sense.
• Versatility:
• Can be used for various tasks like answering questions, writing stories, or helping
homework.
• Adaptable to different subjects and contexts.
• Not Perfect:
• Can make mistakes or provide incorrect information.
• Needs to be used with caution, especially for critical or sensitive topics
Mastering ChatGPT:
Prompt Generation
and Response
Validation
Harness the power of AI for better interactions
and outcomes
AI is not some monstrous job either. It's simply
the latest result of humanity's long-standing
distaste for boredom. Whether the watermills of
millennial past, or the today's lecture room
mechanics, plentiful evidence points to
humanity's long history of creating a paradise to
undertake a repetitive work.
Understanding ChatGPT
• Advanced language
model developed by
OpenAI.
• Generates human-like
text based on the
prompts.
• Quality vs prompt.
Quality of Response ∝ Quality of Prompt × Model Understanding
Here:
Quality of Response is the measure of how relevant, accurate, and coherent the response is.
Quality of Prompt represents the clarity, specificity, and relevance of the prompt given to the model.
Model Understanding , model's ability to interpret the prompt, including its training, design, and current context.
Prompt Generation
Review
prompt
Crafting a
good
prompt
Clear and
Specific.
Specify
type of
Response
Prompt Engineering
• Define the Objective:
• Identify the specific information or assistance
• Be Clear and Precise:
• Use clear language and avoid ambiguity.
• Include essential details without over-
complicating the prompt.
• Consider Context:
• Provide relevant background or context to guide
the response.
• Set the Tone and Style:
• Specify the desired tone (formal, casual) or style
(e.g., summary, explanation) if it matters for your
use case.
• Ask Direct Questions:
• If seeking specific information, formulate your
prompt as a direct question.
• Self Reflective
• Avoid Bias and Leading Questions:
• Craft the prompt neutrally to prevent biased or
skewed responses.
• Test and Refine:
• Experiment with different phrasings and observe
how slight changes can affect the response.
• Refine the prompt
• Consider Ethical and Privacy Concerns:
• Ethical guidelines and does not request or reveal
sensitive or private information.
Bad Prompts Comments Good Prompts Comments
Tell me about heart
problems.
Too vague, lacks
focus and context.
Summarize the diagnostic criteria for
Congestive Heart Failure according to
the latest ACC/AHA guidelines.
Specific, focused, and
references a reputable
source.
What drugs are good
for high BP, diabetes,
and heart issues?
Overly complex,
risks dangerous
oversimplification.
List the first-line antihypertensive
medications according to the latest
guidelines.
Focused on a single
condition, asks for
evidence-based
treatment.
What's the best
treatment for a 45-
year-old male named
John Smith with
these symptoms?
Contains potentially
identifiable
information, risking
patient
confidentiality.
What are the treatment options for a
45-year-old male presenting with
these generic symptoms?
Generalized and
anonymized,
preserving patient
confidentiality.
Response Validation
• Review response - meets your requirements.
• No access to real-time data
• Vaildate Validate Validate.
• Prompt – response -refine - reprompt.
Relevance Check
Accuracy
Confirmation
Context
Consistency
Sensitivity Review
Refinement for
Future Queries
Checklist for Healthcare Prompt Engineering
67-year-old male has
dizziness every time
he sits up from a
lying position,
especially in the
morning. Also, when
he suddenly moves
his head, he notes
the dizziness.
What is the diagnosis
What Are Chatbots?
Patient Triage:
•Appropriate level of
care
Mental Health
Support:
•Immediate, cost-
effective
Patient
Education:
•Provide reliable and
continuous
information, explain
treatment options, or
clarify post-operative
care instructions.
Remote
Monitoring:
•Ensure medication
adherence, and alert
clinicians about
anomalies.
Clinical Decision
Support:
•Data-driven insights
to support clinical
decisions.
Confidentiality and
Compliance:
Ensure that all interactions are
secure and compliant with
healthcare regulations.
AI in Practice for Healthcare Real or Not NHG final (1).pptx
Overcoming Bias
• Anglocentrism
• Contextual Understanding
• Translation Limitations
• Data Imbalance
Relevance to healthcare education
• Adapts to individual student needs
Personalized
Learning:
• Creating diverse and engaging educational materials.
Content Creation:
• Interactive learning experiences (Chatbot)
Student Engagement:
• Provides real-time assessment and feedback .
Assessment and
Feedback:
• content accessible to diverse learners
Accessibility:
• Facilitates collaboration among students and educators,
bridging geographical and language barriers.
Collaboration and
Communication:
Personalized Learning
• Tailors educational content
Adaptive Content Delivery:
• Provides instant feedback and real-time assistance
Real-Time Feedback and
Support:
• Engages with interactive dialogues and Simulates scenarios.
Interactive Learning
Environments:
• Analyses - identify strengths and weaknesses for personalized learning.
Data-Driven Insights:
• Adapts content to diverse learners & multiple languages.
Accessibility and Inclusivity:
• Facilitates collaborative learning experiences and peer interactions.
Collaboration and Peer
Interaction:
• Seamlessly integrates with Learning Management Systems (LMS)
Integration with Existing
Platforms:
• Supports lifelong learning and Assists in tracking and maintaining
professional development
Continuous Learning and Skill
Development:
• Ensures ethical guidelines and privacy regulations.
Ethical and Privacy
Considerations:
• Aligns personalized learning experiences and Ensures relevance to real-
world medical practice
Alignment with Healthcare
Objectives:
Criteria Inadequate (1) Developing (2) Proficient (3) Exemplary (4)
Understanding of
Generative AI Concepts
Demonstrates limited or
incorrect understanding;
fails to integrate into
pedagogy.
Understands basic
principles but
integration into teaching
is superficial.
Strong understanding
and effective integration
into teaching methods.
Expert-level grasp,
including contributions
to curricular
development and
research.
Technical Proficiency in
Generative AI Tools
Struggles to operate
basic functions; no
integration into
teaching.
Can use basic features
but lacks fluency and
instructional application.
Competently uses a
range of features,
enhancing teaching
quality.
Mastery of features,
adapts tools for
specialized instructional
needs.
Data Analysis and
Interpretation
Cannot interpret
Generative AI-generated
data for educational
purposes.
Understands basic
analytics; limited
classroom application.
Proficient in interpreting
data to inform teaching
decisions.
Expert-level analytics
skills, contributing to
research and best
practices.
Pedagogical Integration
Fails to integrate
Generative AI into
pedagogical practices.
Basic integration; limited
impact on teaching
outcomes.
Successfully integrates
Generative AI in various
teaching methods.
Innovates pedagogy
through advanced
Generative AI
integration.
Ethical Awareness and
Application
Unaware or dismissive of
ethical considerations in
using Generative AI.
Basic awareness but
lacks full compliance and
discussion in class.
Adheres to ethical
guidelines and
incorporates discussions
in teaching.
Advocates for ethical use
and contributes to
institutional or field-
wide policies.
Professional
Development
No engagement in
professional
development related to
Generative AI.
Participates in
development sessions
but lacks follow-through.
Actively seeks and
applies new learning in
Generative AI.
Leads professional
development sessions
and contributes to the
literature.
Teacher Competency
Assessment in
Generative AI
Proposed framework by AIDE
AI for Innovative Design & Education
Criteria Inadequate (1) Developing (2) Proficient (3) Exemplary (4)
Understanding of
Generative AI Concepts
Shows limited or
incorrect understanding;
fails in practical
application.
Grasps basic principles
but lacks depth in
coursework or research.
Strong understanding;
can articulate and apply
in academic tasks.
Expert-level
understanding; possibly
contributing to student-
led research or projects.
Technical Proficiency in
Generative AI Tools
Struggles to operate
even basic functions;
poor academic
application.
Capable with basic
features but lacks
advanced skills; limited
research application.
Competently uses a
variety of features for
academic tasks.
Mastery of features;
adapts tools for
specialized academic or
research tasks.
Data Analysis and
Interpretation
Cannot interpret
Generative AI-generated
data for coursework or
research.
Understands basic
outputs; limited
application in academic
tasks.
Proficient in interpreting
a variety of data outputs
for academic uses.
Expert-level analytics;
may contribute to
research or advanced
academic projects.
Academic Application
Fails to apply Generative
AI tools to academic
tasks.
Some application to
academic tasks but lacks
depth.
Consistently applies
Generative AI tools to
enhance academic tasks.
Advanced application,
significantly contributing
to research or
coursework.
Ethical Awareness and
Application
Unaware or ignores
ethical considerations of
using Generative AI.
Basic awareness but
lacks in-depth
understanding and
application.
Adheres to ethical
guidelines and discusses
implications in academic
work.
Advocates for ethical
use; possibly
contributing to student
or institutional policies.
Collaborative Skills
Struggles to collaborate
effectively in Generative
AI tasks.
Can collaborate but
contributes minimally to
the Generative AI
component.
Actively contributes to
collaborative efforts,
enhancing team
performance.
Leads collaborative
projects, optimizing
team performance in
Generative AI
applications.
Student Competency
Assessment in
Generative AI
Proposed framework by AIDE
AI for Innovative Design & Education
Act like a
virtual
patient and
provide me
symptoms
and history
so that I can
improve my
clinical skills
AI in Practice for Healthcare Real or Not NHG final (1).pptx
I have been asked
to create a module
for the
examination of the
abdomen for
organomegaly for
medical students.
Create a
curriculum and
include learning
outcomes and the
pedagogy and a
lesson plan
AI in Practice for Healthcare Real or Not NHG final (1).pptx
Create an
assessment
task and
provide
rubrics for
the
assessment
AI in Practice for Healthcare Real or Not NHG final (1).pptx
AI in Practice for Healthcare Real or Not NHG final (1).pptx
https://creator.nightcafe.studio/
AI in Practice for Healthcare Real or Not NHG final (1).pptx
Educational videos
• Be concise
• Mobile-compatible
• Optimized for social
media
• Enhance blended
learning Average view time of 1.72 min
(103 Seconds)
AI for Video Production
Draft
Learning
Outcomes
LO to Prompt
ChatGPT for
video script
Import/edit
script to AI
Video
Generator
Add
personalised
media
Choose
Voiceover
type
Produce
Review and
Upload
Write a script
for the
introduction of
the anatomy of
the
organomegaly
medical student
module. This
will be a 90
second video
script. Just
provide the
narration
AI generated Instructional Video
Assessment and Feedback
• Automated Grading:
• Grading objective assessments (multiple-choice, fill-in-the-blank, etc.)
• Evaluating subjective assessments (short answers, essays) with predefined criteria
• Personalized Feedback:
• Providing tailored feedback on strengths and areas for improvement
• Engaging in interactive dialogues to reinforce learning concepts
• Real-time Support:
• Offering instant feedback on performance
• Available 24/7 for flexible learning schedules
• Data-Driven Insights:
• Tracking performance over time for individual and class insights
• Designing adaptive learning paths based on student needs
• Enhancing Human Interaction:
• Freeing up educators' time for complex student interactions
• Facilitating structured peer review processes
• Ethical and Bias Considerations:
• Ensuring transparency, fairness, and avoidance of biases in AI-driven assessments
What are the
antibiotics for
leprosy
treatment
Based on
this question
and answer,
create a
rubrics to
mark
answers to
the question
“the antibiotics used in
leprosy are rifampicin
and streptomycin.
Sometimes you can use
dapsone for resistant
cases. Rifampicin is the
first line drug” - based
on this answer provide
a grade for it
AI Tools for RESEARCH
• Elicit for Literature Search
• Scholarcy and Typeset for data
extraction and summary
• Genei.io for summarisation and
key points highlighting
• Keyword generation with ChatGPT
( targeted prompt engineering)
AI in Practice for Healthcare Real or Not NHG final (1).pptx
AI in Practice for Healthcare Real or Not NHG final (1).pptx
Elicit.org
Using SCISPACE
Analyse your documents with Generative AI
Add SciSpace Copilot to your browser
AI research assistant that explains the text, math, and tables in
scientific literature like research papers, technical blog posts, or
reports. You can also ask follow-up questions, and it will give
you instant answers.
Create Account and Login
Choose PDF file to upload
Add to your
collection of
choice and
click DONE
Interrogate
the paper
as per
needs
Input your research topic
Outcome for
Topic Inserted
in search box
Click
Summarized
Abstract to
ADD to
COLUMN in
table
CLICK on a
paper to
see
summaries
and
Interrogate
as per
needs
Typeset.io
The Art and Science of Qualitative Research
https://tinyurl.com/QUALIRE
Introduction to research in healthcare
https://tinyurl.com/HCARERE
AICHAT BT FOR Research in healthcare
https://tinyurl.com/HCAREREBOT
AI-Powered Academic Writing Write Your Research Paper in a Day
https://tinyurl.com/AIAWRITE
AI CHAT BOT for AI_POWERED ACADEMIC WRITING
https://tinyurl.com/AIAWRITEBOT
AI in Practice for Healthcare Real or Not NHG final (1).pptx
Upcoming
• Ministry of Science, Technology
an Innovation, Malaysia
• UNESCO, Thailand
• iCERI, Spain
• Sengkang General Hospital,
Singapore
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AI in Practice for Healthcare Real or Not NHG final (1).pptx

  • 1. Artificial Intelligence in My practice! Real or Not? Vaikunthan Rajaratnam Senior Consultant Hand Surgeon, KTPH, Singapore, Adjunct Professor & UNESCO Chair Partner, Asia Pacific University of Technology and Innovation, Malaysia. 28 September 2023
  • 2. Disclaimer I am not an AI expert, nor do I possess coding knowledge specific to the underlying mechanisms of AI models; my expertise lies in the utilisation of these models, such as ChatGPT, based on my extensive experience as a user within the fields of healthcare, medical education, and related research, rather than their technical development or underlying algorithms.
  • 3. AI for Academic Writing Workshop Write your paper in a day! 8 July 2023 Asia Pacific University of Technology & Innovation (APU) Malaysia
  • 4. AI for Learning Design 26 August 2023 Asia Pacific University of Technology & Innovation (APU)
  • 5. AI in Healthcare: Unleashing the Power in a One-Day Workshop Empowering Healthcare Professionals to Leverage AI in Practice 7 September 2023
  • 7. Introduction to AI in Healthcare: Opportunities and Challenges AI technologies have the potential to revolutionize healthcare by enhancing diagnosis, treatment planning, and research.
  • 8. Understanding AI, Generative AI, and ChatGPT • AI (Artificial Intelligence) • refers to the simulation of human intelligence in machines that are programmed to think, learn, and make decisions • Applications: Includes machine learning, natural language processing, robotics, computer vision, etc. • Generative AI • subset of AI that focuses on creating new data instances that are similar to a set of training examples. • Techniques: Examples include Generative Adversarial Networks (GANs), Variational Autoencoders (VAEs), etc. • ChatGPT (Generative Pretrained Transformer): • State-of-the-art language models developed by OpenAI. It utilises the Transformer architecture to generate human-like text based on given prompts. • Usage: Widely used in natural language understanding tasks, chatbots, content creation, and more.
  • 9. Suero-Abreu, G. A., Hamid, A., Akbilgic, O., & Brown, S.-A. (2022). Trends in cardiology and oncology artificial intelligence publications. American Heart Journal Plus: Cardiology Research and Practice, 17, 100162. https://doi.org/10.1016/j.ahjo.2022.100162
  • 10. • Rapid multi-disciplinary stream of authors researching AI in Medicine • Skills and data quality awareness for data- intensive analysis • Limitations • Ethics, • Data governance, and • Competencies of the health workforce. • Focuses on • Health services management • Predictive medicine • Patient data and diagnostics • Clinical decision-making Secinaro, S., Calandra, D., Secinaro, A., Muthurangu, V., & Biancone, P. (2021). The role of artificial intelligence in healthcare: A structured literature review. BMC Medical Informatics and Decision Making, 21(1), 125. https://doi.org/10.1186/s12911-021-01488-9
  • 11. Health services managemen t • Optimization of Operational Efficiency • Example: Scheduling algorithms to optimize staff shifts and patient appointments, reducing wait times. • Predictive Analytics for Resource Allocation • Example: Predicting hospital bed occupancy based on patient flow and admission trends for better resource planning. • Supply Chain Optimization • Example: Forecasting the need for medical supplies and automating procurement to reduce inventory costs. • Fraud Detection and Compliance • Example: Detecting fraudulent billing activities and ensuring compliance with healthcare regulations. • Integration of Care across Providers • Example: Facilitating seamless information sharing among healthcare providers for coordinated care. • Enhancing Administrative Decision-Making • Example: Utilizing data analytics to inform strategic decisions, such as facility expansion or service prioritization. • Patient Engagement and Communication • Example: AI-powered chatbots to handle routine inquiries, appointment scheduling, and patient follow- ups. • Workforce Development and Training • Example: Using AI to identify training needs and deliver personalized learning paths for healthcare staff. • Performance Monitoring and Quality Assurance • Example: Implementing AI-driven analytics to monitor performance metrics, identify areas for improvement, and ensure quality standards. • Cost Control and Optimization • Example: Applying AI to analyze cost drivers, identify inefficiencies, and recommend cost-saving measures.
  • 12. Predictiv e medicine • Early Disease Detection • Example: Using AI algorithms to analyze medical imaging for early detection of cancers, even before symptoms appear. • Risk Stratification • Example: Identifying patients at high risk of chronic conditions like heart disease based on a combination of genetic, lifestyle, and clinical data. • Personalized Treatment Plans • Example: Creating tailored treatment regimens by predicting individual responses to specific drugs or therapies. • Epidemic Outbreak Prediction • Example: Analyzing social media, travel patterns, and other data sources to predict the spread of infectious diseases like flu or COVID-19. • Hospital Readmission Prediction • Example: Determining the likelihood of a patient's readmission to the hospital, allowing for targeted interventions to reduce readmissions. • Drug Response Prediction • Example: Predicting how individual patients will respond to certain medications, minimizing adverse effects, and improving treatment efficacy. • Genomic Medicine and Genetic Risk Prediction • Example: Analyzing genetic data to predict susceptibility to genetic disorders and guide preventive measures. • Mental Health Outcome Prediction • Example: Utilizing AI to predict mental health crises or progression of conditions like depression based on patient behavior and medical history. • Chronic Disease Management • Example: Continuous monitoring and prediction of disease progression in chronic conditions like diabetes, allowing for timely interventions.
  • 13. Patient data and diagnostics • Automated Data Analysis and Interpretation • Example: Using AI to analyze complex laboratory results, such as genetic sequencing, to identify patterns and anomalies. • Real-Time Monitoring and Alerting • Example: Continuously tracking vital signs and alerting medical staff to potential issues, such as deterioration in a patient's condition. • Enhanced Medical Imaging Interpretation • Example: Applying AI algorithms to interpret radiological images, such as X-rays and MRIs, with increased accuracy and speed. • Predictive Analytics for Personalized Care • Example: Analyzing patient data to predict individual responses to treatments, enabling more personalized and effective care plans. • Data Integration and Holistic Patient Views • Example: Aggregating data from various sources (e.g., EMRs, wearables) to provide a comprehensive view of a patient's health status. • Telemedicine and Remote Diagnostics • Example: Utilizing AI-powered tools to diagnose and manage patients in remote locations, increasing healthcare accessibility. • Natural Language Processing for Clinical Notes • Example: Extracting valuable information from unstructured clinical notes through AI, enhancing data usability. • Genomic and Precision Medicine • Example: Integrating genomic data with clinical information to provide precise diagnoses and personalized treatment recommendations. • Chronic Condition Management and Monitoring • Example: Using AI to diagnose and monitor chronic conditions, such as diabetes, through continuous data analysis. • Ethical and Security Considerations in Data Handling • Example: Implementing AI-driven security protocols to ensure patient data privacy and compliance with regulations.
  • 14. Clinical decision- making • Evidence-Based Recommendations • Example: AI systems can analyze vast medical literature to provide evidence-based treatment recommendations tailored to individual patient profiles. • Diagnostic Support Tools • Example: AI algorithms can assist physicians in diagnosing complex conditions by analyzing clinical data, medical imaging, and laboratory results. • Predicting Patient Outcomes • Example: Using AI to predict patient responses to various treatments, aiding in selecting the most effective therapy. • Treatment Pathway Optimization • Example: AI can suggest optimal treatment pathways based on patient characteristics, medical history, and current clinical guidelines. • Enhancing Multidisciplinary Collaboration • Example: AI-driven platforms can facilitate collaboration among specialists, integrating insights from various disciplines for comprehensive care. • Ethical Considerations in Decision Making • Example: Implementing AI algorithms that consider ethical principles, such as fairness and transparency, in clinical
  • 15. Challenges • Data • Trust • Ethics • Readiness for change, • Expertise • Buy-in • Regulatory strategy • Scalability • Evaluation Golhar, S. P., & Kekapure, S. S. (2022). Artificial Intelligence in Healthcare—A Review. International Journal of Scientific Research in Science and Technology, 9(4), 381–387. https://doi.org/10.32628/IJSRST229454
  • 16. Governance Model for AI S. Reddy, S. Allan, S. Coghlan, and P. Cooper, ‘A governance model for the application of AI in health care’, J. Am. Med. Inform. Assoc., vol. 27, no. 3, pp. 491–497, Mar. 2020, doi: 10.1093/jamia/ocz192 Rahman, N., Thamotharampillai, T., & Rajaratnam, V. (2023). Ethics, guidelines, and policy for technology in healthcare. In Medical Equipment Engineering: Design, Manufacture and Applications (pp. 119–147). IET Digital Library. https://doi.org/10.1049/PBHE054E_ch9
  • 17. Higgins, D., & Madai, V. I. (2020). From Bit to Bedside: A Practical Framework for Artificial Intelligence Product Development in Healthcare. Advanced Intelligent Systems, 2(10), 2000052. https://doi.org/10.1002/aisy.202000052
  • 18. What is ChatGPT? • Understanding Language • Reads and comprehends human-written text. • Generating Text • Writes human-like text, from answers to creative content. • Conversation • Capable of engaging in text-based conversations with users. • Applications • Used in virtual assistants, education, content creation, and more. • Not a Human • Generates text through algorithms, without feelings or consciousness. AI for Clinical Decision-Making and Patient Care
  • 19. How Does ChatGPT Work? “Don’t cry ………..” “ Don’t cry over….” • Reading Text: • Takes in words, questions, or sentences as input. • Understands the language like a human reading a book. • Processing Information: • Breaks down the input into smaller parts to understand the meaning. • Uses a complex mathematical model to analyse the text. • Generating Response: • Constructs a response based on what it has "learned" from reading lots of text. • Tries to make the response sound like something a human would say. • No Personal Knowledge or Opinions: • Doesn't have thoughts, feelings, or personal experiences. • Answers are based on patterns in the data it was trained on, not personal beliefs opinions. • Learning from Data: • Trained on a vast amount of text from books, websites, and other written materia • Learns the structure of language and how to create sentences that make sense. • Versatility: • Can be used for various tasks like answering questions, writing stories, or helping homework. • Adaptable to different subjects and contexts. • Not Perfect: • Can make mistakes or provide incorrect information. • Needs to be used with caution, especially for critical or sensitive topics
  • 20. Mastering ChatGPT: Prompt Generation and Response Validation Harness the power of AI for better interactions and outcomes AI is not some monstrous job either. It's simply the latest result of humanity's long-standing distaste for boredom. Whether the watermills of millennial past, or the today's lecture room mechanics, plentiful evidence points to humanity's long history of creating a paradise to undertake a repetitive work.
  • 21. Understanding ChatGPT • Advanced language model developed by OpenAI. • Generates human-like text based on the prompts. • Quality vs prompt. Quality of Response ∝ Quality of Prompt × Model Understanding Here: Quality of Response is the measure of how relevant, accurate, and coherent the response is. Quality of Prompt represents the clarity, specificity, and relevance of the prompt given to the model. Model Understanding , model's ability to interpret the prompt, including its training, design, and current context.
  • 22. Prompt Generation Review prompt Crafting a good prompt Clear and Specific. Specify type of Response
  • 23. Prompt Engineering • Define the Objective: • Identify the specific information or assistance • Be Clear and Precise: • Use clear language and avoid ambiguity. • Include essential details without over- complicating the prompt. • Consider Context: • Provide relevant background or context to guide the response. • Set the Tone and Style: • Specify the desired tone (formal, casual) or style (e.g., summary, explanation) if it matters for your use case. • Ask Direct Questions: • If seeking specific information, formulate your prompt as a direct question. • Self Reflective • Avoid Bias and Leading Questions: • Craft the prompt neutrally to prevent biased or skewed responses. • Test and Refine: • Experiment with different phrasings and observe how slight changes can affect the response. • Refine the prompt • Consider Ethical and Privacy Concerns: • Ethical guidelines and does not request or reveal sensitive or private information.
  • 24. Bad Prompts Comments Good Prompts Comments Tell me about heart problems. Too vague, lacks focus and context. Summarize the diagnostic criteria for Congestive Heart Failure according to the latest ACC/AHA guidelines. Specific, focused, and references a reputable source. What drugs are good for high BP, diabetes, and heart issues? Overly complex, risks dangerous oversimplification. List the first-line antihypertensive medications according to the latest guidelines. Focused on a single condition, asks for evidence-based treatment. What's the best treatment for a 45- year-old male named John Smith with these symptoms? Contains potentially identifiable information, risking patient confidentiality. What are the treatment options for a 45-year-old male presenting with these generic symptoms? Generalized and anonymized, preserving patient confidentiality.
  • 25. Response Validation • Review response - meets your requirements. • No access to real-time data • Vaildate Validate Validate. • Prompt – response -refine - reprompt. Relevance Check Accuracy Confirmation Context Consistency Sensitivity Review Refinement for Future Queries
  • 26. Checklist for Healthcare Prompt Engineering
  • 27. 67-year-old male has dizziness every time he sits up from a lying position, especially in the morning. Also, when he suddenly moves his head, he notes the dizziness. What is the diagnosis
  • 29. Patient Triage: •Appropriate level of care Mental Health Support: •Immediate, cost- effective Patient Education: •Provide reliable and continuous information, explain treatment options, or clarify post-operative care instructions. Remote Monitoring: •Ensure medication adherence, and alert clinicians about anomalies. Clinical Decision Support: •Data-driven insights to support clinical decisions. Confidentiality and Compliance: Ensure that all interactions are secure and compliant with healthcare regulations.
  • 31. Overcoming Bias • Anglocentrism • Contextual Understanding • Translation Limitations • Data Imbalance
  • 32. Relevance to healthcare education • Adapts to individual student needs Personalized Learning: • Creating diverse and engaging educational materials. Content Creation: • Interactive learning experiences (Chatbot) Student Engagement: • Provides real-time assessment and feedback . Assessment and Feedback: • content accessible to diverse learners Accessibility: • Facilitates collaboration among students and educators, bridging geographical and language barriers. Collaboration and Communication:
  • 33. Personalized Learning • Tailors educational content Adaptive Content Delivery: • Provides instant feedback and real-time assistance Real-Time Feedback and Support: • Engages with interactive dialogues and Simulates scenarios. Interactive Learning Environments: • Analyses - identify strengths and weaknesses for personalized learning. Data-Driven Insights: • Adapts content to diverse learners & multiple languages. Accessibility and Inclusivity: • Facilitates collaborative learning experiences and peer interactions. Collaboration and Peer Interaction: • Seamlessly integrates with Learning Management Systems (LMS) Integration with Existing Platforms: • Supports lifelong learning and Assists in tracking and maintaining professional development Continuous Learning and Skill Development: • Ensures ethical guidelines and privacy regulations. Ethical and Privacy Considerations: • Aligns personalized learning experiences and Ensures relevance to real- world medical practice Alignment with Healthcare Objectives:
  • 34. Criteria Inadequate (1) Developing (2) Proficient (3) Exemplary (4) Understanding of Generative AI Concepts Demonstrates limited or incorrect understanding; fails to integrate into pedagogy. Understands basic principles but integration into teaching is superficial. Strong understanding and effective integration into teaching methods. Expert-level grasp, including contributions to curricular development and research. Technical Proficiency in Generative AI Tools Struggles to operate basic functions; no integration into teaching. Can use basic features but lacks fluency and instructional application. Competently uses a range of features, enhancing teaching quality. Mastery of features, adapts tools for specialized instructional needs. Data Analysis and Interpretation Cannot interpret Generative AI-generated data for educational purposes. Understands basic analytics; limited classroom application. Proficient in interpreting data to inform teaching decisions. Expert-level analytics skills, contributing to research and best practices. Pedagogical Integration Fails to integrate Generative AI into pedagogical practices. Basic integration; limited impact on teaching outcomes. Successfully integrates Generative AI in various teaching methods. Innovates pedagogy through advanced Generative AI integration. Ethical Awareness and Application Unaware or dismissive of ethical considerations in using Generative AI. Basic awareness but lacks full compliance and discussion in class. Adheres to ethical guidelines and incorporates discussions in teaching. Advocates for ethical use and contributes to institutional or field- wide policies. Professional Development No engagement in professional development related to Generative AI. Participates in development sessions but lacks follow-through. Actively seeks and applies new learning in Generative AI. Leads professional development sessions and contributes to the literature. Teacher Competency Assessment in Generative AI Proposed framework by AIDE AI for Innovative Design & Education
  • 35. Criteria Inadequate (1) Developing (2) Proficient (3) Exemplary (4) Understanding of Generative AI Concepts Shows limited or incorrect understanding; fails in practical application. Grasps basic principles but lacks depth in coursework or research. Strong understanding; can articulate and apply in academic tasks. Expert-level understanding; possibly contributing to student- led research or projects. Technical Proficiency in Generative AI Tools Struggles to operate even basic functions; poor academic application. Capable with basic features but lacks advanced skills; limited research application. Competently uses a variety of features for academic tasks. Mastery of features; adapts tools for specialized academic or research tasks. Data Analysis and Interpretation Cannot interpret Generative AI-generated data for coursework or research. Understands basic outputs; limited application in academic tasks. Proficient in interpreting a variety of data outputs for academic uses. Expert-level analytics; may contribute to research or advanced academic projects. Academic Application Fails to apply Generative AI tools to academic tasks. Some application to academic tasks but lacks depth. Consistently applies Generative AI tools to enhance academic tasks. Advanced application, significantly contributing to research or coursework. Ethical Awareness and Application Unaware or ignores ethical considerations of using Generative AI. Basic awareness but lacks in-depth understanding and application. Adheres to ethical guidelines and discusses implications in academic work. Advocates for ethical use; possibly contributing to student or institutional policies. Collaborative Skills Struggles to collaborate effectively in Generative AI tasks. Can collaborate but contributes minimally to the Generative AI component. Actively contributes to collaborative efforts, enhancing team performance. Leads collaborative projects, optimizing team performance in Generative AI applications. Student Competency Assessment in Generative AI Proposed framework by AIDE AI for Innovative Design & Education
  • 36. Act like a virtual patient and provide me symptoms and history so that I can improve my clinical skills
  • 38. I have been asked to create a module for the examination of the abdomen for organomegaly for medical students. Create a curriculum and include learning outcomes and the pedagogy and a lesson plan
  • 45. Educational videos • Be concise • Mobile-compatible • Optimized for social media • Enhance blended learning Average view time of 1.72 min (103 Seconds)
  • 46. AI for Video Production Draft Learning Outcomes LO to Prompt ChatGPT for video script Import/edit script to AI Video Generator Add personalised media Choose Voiceover type Produce Review and Upload
  • 47. Write a script for the introduction of the anatomy of the organomegaly medical student module. This will be a 90 second video script. Just provide the narration
  • 49. Assessment and Feedback • Automated Grading: • Grading objective assessments (multiple-choice, fill-in-the-blank, etc.) • Evaluating subjective assessments (short answers, essays) with predefined criteria • Personalized Feedback: • Providing tailored feedback on strengths and areas for improvement • Engaging in interactive dialogues to reinforce learning concepts • Real-time Support: • Offering instant feedback on performance • Available 24/7 for flexible learning schedules • Data-Driven Insights: • Tracking performance over time for individual and class insights • Designing adaptive learning paths based on student needs • Enhancing Human Interaction: • Freeing up educators' time for complex student interactions • Facilitating structured peer review processes • Ethical and Bias Considerations: • Ensuring transparency, fairness, and avoidance of biases in AI-driven assessments
  • 50. What are the antibiotics for leprosy treatment
  • 51. Based on this question and answer, create a rubrics to mark answers to the question
  • 52. “the antibiotics used in leprosy are rifampicin and streptomycin. Sometimes you can use dapsone for resistant cases. Rifampicin is the first line drug” - based on this answer provide a grade for it
  • 53. AI Tools for RESEARCH • Elicit for Literature Search • Scholarcy and Typeset for data extraction and summary • Genei.io for summarisation and key points highlighting • Keyword generation with ChatGPT ( targeted prompt engineering)
  • 57. Using SCISPACE Analyse your documents with Generative AI
  • 58. Add SciSpace Copilot to your browser AI research assistant that explains the text, math, and tables in scientific literature like research papers, technical blog posts, or reports. You can also ask follow-up questions, and it will give you instant answers.
  • 60. Choose PDF file to upload
  • 61. Add to your collection of choice and click DONE
  • 66. CLICK on a paper to see summaries and Interrogate as per needs
  • 68. The Art and Science of Qualitative Research https://tinyurl.com/QUALIRE Introduction to research in healthcare https://tinyurl.com/HCARERE AICHAT BT FOR Research in healthcare https://tinyurl.com/HCAREREBOT AI-Powered Academic Writing Write Your Research Paper in a Day https://tinyurl.com/AIAWRITE AI CHAT BOT for AI_POWERED ACADEMIC WRITING https://tinyurl.com/AIAWRITEBOT
  • 70. Upcoming • Ministry of Science, Technology an Innovation, Malaysia • UNESCO, Thailand • iCERI, Spain • Sengkang General Hospital, Singapore

Editor's Notes

  1. The clinical domain refers to identifying real‐world clinical needs and validating these needs throughout the life cycle of the project. Herein, the major risks, objectives and key results, and practical advice, across the three time‐phases of development, are presented. IF THIS IMAGE HAS BEEN PROVIDED BY OR IS OWNED BY A THIRD PARTY, AS INDICATED IN THE CAPTION LINE, THEN FURTHER PERMISSION MAY BE NEEDED BEFORE ANY FURTHER USE. PLEASE CONTACT WILEY'S PERMISSIONS DEPARTMENT ON PERMISSIONS@WILEY.COM OR USE THE RIGHTSLINK SERVICE BY CLICKING ON THE 'REQUEST PERMISSIONS' LINK ACCOMPANYING THIS ARTICLE. WILEY OR AUTHOR OWNED IMAGES MAY BE USED FOR NON-COMMERCIAL PURPOSES, SUBJECT TO PROPER CITATION OF THE ARTICLE, AUTHOR, AND PUBLISHER.