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CHORDOMA
• CLINICALLY MALIGNANT TUMOUR ARISING
FROM THE NOTOCHORD REMNANT
• NOTOCHORD REMNANT LEFT AT TWO PLACES
– CLIVUS
– SACROCO...
CLIVAL
SACROCOCYGEAL
CLIVAL CHORDOMA
HISTOLOGICAL VARIANTS
• THREE VARIANTS
– CHONDROID CHORDOMA
– PHYSALIFEROUS CELLS
– DE DIFFERENTIATED
PHYSALIFEROUS CELLS
• IN THIS, VARIETY TUMOUR CELLS ARRANGED
IN LOBULES, THE TUMOUR CELLS CONTAINING
SMALL NUCLEI AND VACU...
CHONDROID CHORDOMA
• CHONDROSARCOMA FEATURES + CHORDOMA
• CHONDROSARCOMA FEATURE
– HYPERGLYCEMIA
• DEDIFFERENTIATED VARIETY
MANGEMENT
• SURGERY + RADIOTHERAPY
• (CARE MUST BE TAKEN FOR CLIVAL
CHORDOMA)
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Chordoma

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CHORDOMA
DEFINITION
TYPES- CLIVAL AND SACROCOCCYGEAL
HISTOLOGICAL TYPES - 3 TYPES
""PHYSALIFEROUS CELLS""
MANAGEMENT

Published in: Education
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Chordoma

  1. 1. CHORDOMA
  2. 2. • CLINICALLY MALIGNANT TUMOUR ARISING FROM THE NOTOCHORD REMNANT • NOTOCHORD REMNANT LEFT AT TWO PLACES – CLIVUS – SACROCOCCYGEAL AREA
  3. 3. CLIVAL
  4. 4. SACROCOCYGEAL
  5. 5. CLIVAL CHORDOMA
  6. 6. HISTOLOGICAL VARIANTS • THREE VARIANTS – CHONDROID CHORDOMA – PHYSALIFEROUS CELLS – DE DIFFERENTIATED
  7. 7. PHYSALIFEROUS CELLS • IN THIS, VARIETY TUMOUR CELLS ARRANGED IN LOBULES, THE TUMOUR CELLS CONTAINING SMALL NUCLEI AND VACUOLATED CYTOPLASM
  8. 8. CHONDROID CHORDOMA • CHONDROSARCOMA FEATURES + CHORDOMA • CHONDROSARCOMA FEATURE – HYPERGLYCEMIA
  9. 9. • DEDIFFERENTIATED VARIETY
  10. 10. MANGEMENT • SURGERY + RADIOTHERAPY • (CARE MUST BE TAKEN FOR CLIVAL CHORDOMA)

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