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Update on PEDV
Lisa Becton, DVM, MS
National Pork Board
Porcine Epidemic Diarrhea Virus (PEDV)
• Overview of the disease
• Current US status
• Actions to manage PEDV
• American A...
PEDV – Initial focus
• Coordinated effort by all key stakeholders to
understand where PEDV was/is occurring and
how to bes...
PEDV – what is it?
• PEDV is a diarrheal disease of pigs that has
recently been found in the United States and is
similar ...
PEDV – What it is…
• PEDV currently exists in many different parts of
the world
• Considered to be a production disease
• ...
PEDV – What it is NOT…
• Not zoonotic
• Not a food safety concern
• Not a listed disease of the OIE
• Not on the National ...
PEDV – What are the symptoms?
• PEDV symptoms can vary from TGE but are
generally similar:
– Symptoms on farm can range fr...
PEDV – How is it diagnosed?
• Laboratory confirmation is the only way to
diagnose and differentiate PEDV from TGE
– Many d...
PEDV – What is the current status?
• Positive samples have been identified in multiple
states
• PEDV has been identified i...
PEDV – status of sampling
• Confirmation of the disease has been from
samples taken from sick pigs
• After the initial dia...
PEDV – What’s next?
2013 Supplemental Funding PED research
•Speed and effectiveness
•Transparent and objective
•Targeted p...
Porcine Epidemic Diarrhea - PED
2013 Supplemental Funding request: $410,000
•PEDV Needs
– Support current “entry” survey
–...
PEDV – What’s next?
• Work with the Swine Health Committee, AASV,
NPPC and other key stakeholders to initiate the
research...
PEDv Investigation 2013
Survey Instrument
Primary infection
First site/herd – confirmed positive PEDv
Any stage of production
Risk factors – c...
Information Gathering
Herd information
# & type on site
Nearby farms
Biosecurity
Entries onto site
Trucks/trailers
...
Information Gathering - continued
Inputs
Semen
Vaccines
Feed
Feed supplements/base mix/premix
Protein
Characterize the clinical presentations
on the farm
Clinical signs
Date of onset
Morbidity
Mortality
Samples to veter...
Data Analysis
National Center for Foreign Animal &
Zoonotic Disease Defense (FAZD)
US Department of Agriculture – Center...
Next Steps
Lateral transmission
Containment & elimination?
Hypotheses generation
Further research
This message funded by America’s Pork Checkoff Program.
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Dr. Lisa Becton and Dr. Tom Burkgren - Update on Porcine Epidemic Diarrhea Virus (PEDV): What is it and how will it affect me?

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Update on Porcine Epidemic Diarrhea Virus (PEDV): What is it and how will it affect me? - Dr. Lisa Becton, National Pork Board, and Dr. Tom Burkgren, AASV, from the 2013 World Pork Expo, June 5 - 7, 2013, Des Moines, IA, USA.

More presentations at http://www.swinecast.com/2013-world-pork-expo

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Dr. Lisa Becton and Dr. Tom Burkgren - Update on Porcine Epidemic Diarrhea Virus (PEDV): What is it and how will it affect me?

  1. 1. Update on PEDV Lisa Becton, DVM, MS National Pork Board
  2. 2. Porcine Epidemic Diarrhea Virus (PEDV) • Overview of the disease • Current US status • Actions to manage PEDV • American Association of Swine Veterinarians review • Q/A
  3. 3. PEDV – Initial focus • Coordinated effort by all key stakeholders to understand where PEDV was/is occurring and how to best manage it: – United States Department of Agriculture (multiple divisions) – National Pork Board – National Pork Producers Council – American Association of Swine Veterinarians
  4. 4. PEDV – what is it? • PEDV is a diarrheal disease of pigs that has recently been found in the United States and is similar to the TGE virus (Transmissible Gastroenteritis virus) • PEDV was confirmed in the US on May 16th , 2013 by diagnostic tests at the USDA National Veterinary Services Laboratory (NVSL) in Ames, IA
  5. 5. PEDV – What it is… • PEDV currently exists in many different parts of the world • Considered to be a production disease • Can be managed/controlled/eliminated with targeted biosecurity efforts
  6. 6. PEDV – What it is NOT… • Not zoonotic • Not a food safety concern • Not a listed disease of the OIE • Not on the National Animal Health Reporting System (NAHRS) Reportable Disease List • Not considered a Foreign Animal Disease in the United States • No interstate trade restrictions pertaining to PEDV
  7. 7. PEDV – What are the symptoms? • PEDV symptoms can vary from TGE but are generally similar: – Symptoms on farm can range from mild to rapid and explosive spread – Diarrhea and vomiting in pigs of all ages • Most severe in baby pigs – Mortality ~ 100% for pigs < 7 days of age – Mortality ~ 90% in pigs 8-21 days of age • Sows and older growing swine can show various degrees of illness, but generally more mild than baby pigs
  8. 8. PEDV – How is it diagnosed? • Laboratory confirmation is the only way to diagnose and differentiate PEDV from TGE – Many different labs working together to have needed diagnostic tests available: Iowa State, University of Minnesota, Kansas State, South Dakota State, NVSL • Current diarrheal cases have detected TGE, so it is very important to work with your veterinarian for an accurate diagnosis!
  9. 9. PEDV – What is the current status? • Positive samples have been identified in multiple states • PEDV has been identified in both sow farms as well as growing pig sites • Are there concerns about other potential sources of PEDV?
  10. 10. PEDV – status of sampling • Confirmation of the disease has been from samples taken from sick pigs • After the initial diagnosis of PEDV, concerns arose that feed or ingredients might be a potential source of PEDV – USDA has worked closely with the Food and Drug Administration (FDA) to sample feedstuffs – No positive samples have been identified to date – However, testing is ongoing
  11. 11. PEDV – What’s next? 2013 Supplemental Funding PED research •Speed and effectiveness •Transparent and objective •Targeted projects with short timeframes •Flexibility with oversight of Swine Health Committee leadership 11
  12. 12. Porcine Epidemic Diarrhea - PED 2013 Supplemental Funding request: $410,000 •PEDV Needs – Support current “entry” survey – Support next “epidemiology” survey – Carrier, immunity, transmission, challenge – Diagnostic tools and validation – Viral propagation and survival 12
  13. 13. PEDV – What’s next? • Work with the Swine Health Committee, AASV, NPPC and other key stakeholders to initiate the research process for PEDV • Goal is to rapidly respond and provide needed information regarding PEDV for management of this virus
  14. 14. PEDv Investigation 2013
  15. 15. Survey Instrument Primary infection First site/herd – confirmed positive PEDv Any stage of production Risk factors – common to all or many confirmed positive cases Characterize the clinical presentation Also survey negative herd – case control for comparison
  16. 16. Information Gathering Herd information # & type on site Nearby farms Biosecurity Entries onto site Trucks/trailers Security breaches
  17. 17. Information Gathering - continued Inputs Semen Vaccines Feed Feed supplements/base mix/premix Protein
  18. 18. Characterize the clinical presentations on the farm Clinical signs Date of onset Morbidity Mortality Samples to veterinary diagnostic laboratory Recovery
  19. 19. Data Analysis National Center for Foreign Animal & Zoonotic Disease Defense (FAZD) US Department of Agriculture – Center for Epidemiology And Animal Health (CEAH) National Pork Board National Pork Producers Council American Association of Swine Veterinarians
  20. 20. Next Steps Lateral transmission Containment & elimination? Hypotheses generation Further research
  21. 21. This message funded by America’s Pork Checkoff Program. Questions?

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