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Anastrozole Tablets 
Anastrozole tablets (Anazole) is used for the treatment of 
breast cancer in hormone receptor positiv...
Anastrozole Tablets 
Chemical Structure 
© The Swiss Pharmacy, Geneva Switzerland
Anastrozole Tablets 
Active Ingredient 
The active pharmaceutical ingredient 
contained in Anazole tablets is 
Anastrozole...
Anastrozole Tablets 
Recommended Dosage 
➔ Adults: 
➔One tablet (1 mg) of Anastrozole tablets (Anazole) 
has to be taken o...
Anastrozole Tablets 
Contraindications 
Generic Anastrozole Tablets 
(Anazole) is contraindicated in 
patients with the fo...
Anastrozole Tablets 
Side Effects of Anastrozole Tablets (Anazole) 
The most common possible side effects of 
Anastrozole ...
Anastrozole Tablets 
Warnings And Precautions 
➔Anastrozole is not recommended for use in children or in 
pre-menopausal w...
Anastrozole Tablets 
Warnings And Precautions 
➔As Anastrozole lowers circulating oestrogen levels it 
may cause a decreas...
Anastrozole Tablets 
Anastrozole Overdose 
Clinical trials have been conducted with a range of 
doses of Anastrozole table...
Anastrozole Tablets 
Overdose Treatment 
There is no specific antidote to overdosage and 
treatment must be symptomatic. I...
Anastrozole Tablets 
Anazole Tablets 1 mg from 
Alpha Pharma Ltd., India 
For more information click here 
© The Swiss Pha...
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Anastrozole Tablets for Treatment of Breast Cancer in Post-menopausal Women

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Anastrozole tablets (Anazole) is used for the treatment of breast cancer in hormone receptor positive post-menopausal women. It is also used for adjuvant treatment of early breast cancer in hormone receptor positive postmenopausal women who have received 2 to 3 years of adjuvant Tamoxifen as well as reduction in the incidence of contralateral breast cancers in post menopausal women receiving Anastrozole tablets as adjuvant treatment for early breast cancer.

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Anastrozole Tablets for Treatment of Breast Cancer in Post-menopausal Women

  1. 1. Anastrozole Tablets Anastrozole tablets (Anazole) is used for the treatment of breast cancer in hormone receptor positive post-menopausal women. It is also used for adjuvant treatment of early breast cancer in hormone receptor positive postmenopausal women who have received 2 to 3 years of adjuvant Tamoxifen as well as reduction in the incidence of contralateral breast cancers in post menopausal women receiving Anastrozole tablets as adjuvant treatment for early breast cancer. © The Swiss Pharmacy, Geneva Switzerland
  2. 2. Anastrozole Tablets Chemical Structure © The Swiss Pharmacy, Geneva Switzerland
  3. 3. Anastrozole Tablets Active Ingredient The active pharmaceutical ingredient contained in Anazole tablets is Anastrozole. Each 1 mg tablet of Anazole contains 1mg Anastrozole. © The Swiss Pharmacy, Geneva Switzerland
  4. 4. Anastrozole Tablets Recommended Dosage ➔ Adults: ➔One tablet (1 mg) of Anastrozole tablets (Anazole) has to be taken orally once a day. Anastrozole can be taken with or without food. © The Swiss Pharmacy, Geneva Switzerland
  5. 5. Anastrozole Tablets Contraindications Generic Anastrozole Tablets (Anazole) is contraindicated in patients with the following conditions: ➔Known hypersensitivity to Anastrozole or any inactive ingredient of this medication. ➔Anastrozole tablets (Anazole) should not be used in pregnant or lactating women. © The Swiss Pharmacy, Geneva Switzerland
  6. 6. Anastrozole Tablets Side Effects of Anastrozole Tablets (Anazole) The most common possible side effects of Anastrozole Tablets occurring in 1% or more of the patients are Hot flushes, Gastrointestinal upsets including nausea and diarrhoea, Headache, Rash, Loss of hair, Vaginal dryness, Asthenia, joint pain or stiffness, Carpal Tunnel Syndrome, Increases in alkaline phosphatase, alanine aminotransferase and aspartate aminotransferase. © The Swiss Pharmacy, Geneva Switzerland
  7. 7. Anastrozole Tablets Warnings And Precautions ➔Anastrozole is not recommended for use in children or in pre-menopausal women as safety and efficacy have not been established in these groups of patients. ➔In women with pre-existing ischemic heart disease, an increased incidence of ischemic cardiovascular events occurred with Anastrozole use compared to Tamoxifen use. Consider risks and benefits. ➔Increases in total cholesterol may occur in patients administered Anastrozole. Consider cholesterol monitoring. © The Swiss Pharmacy, Geneva Switzerland
  8. 8. Anastrozole Tablets Warnings And Precautions ➔As Anastrozole lowers circulating oestrogen levels it may cause a decrease in bone mineral density with a possible consequent increased risk of fracture. Studies have showed that patients receiving Anastrozole tablets (Anazole) had a mean decrease in both lumbar spine and total hip bone mineral density (BMD) compared to baseline. Consider bone mineral density monitoring. ➔Anastrozole tablets (Anazole) has not been investigated in patients with severe hepatic or severe renal impairment. The potential risk/benefit to such patients should be carefully considered before administration of Anastrozole tablets. © The Swiss Pharmacy, Geneva Switzerland
  9. 9. Anastrozole Tablets Anastrozole Overdose Clinical trials have been conducted with a range of doses of Anastrozole tablets, up to 60 mg in a single dose given to healthy male volunteers and up to 10 mg daily given to post-menopausal women with advanced breast cancer; these dosages were well tolerated. A single dose of Anastrozole tablets that results in life-threatening symptoms has not been established. Acute toxicity was seen in animals at a dose greater than 45 mg/kg (equivalent to 2.7 g). © The Swiss Pharmacy, Geneva Switzerland
  10. 10. Anastrozole Tablets Overdose Treatment There is no specific antidote to overdosage and treatment must be symptomatic. In the management of an overdose, consider that multiple agents may have been taken. Vomiting may be induced if the patient is alert. Dialysis may be helpful because Anastrozole is not highly protein bound. General supportive care, including frequent monitoring of vital signs and close observation of the patient, is indicated. © The Swiss Pharmacy, Geneva Switzerland
  11. 11. Anastrozole Tablets Anazole Tablets 1 mg from Alpha Pharma Ltd., India For more information click here © The Swiss Pharmacy, Geneva Switzerland

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