In this talk we present various issues that need to be considered when SMEs may take the roles of suppliers, producers, distributors, and customers in supply chain networks. We also discuss the benefits and the difficulties that SMEs as well as large firms can face as being part of the same supply chain network. Oya Tukel, Ph.D., Cleveland State University Nance College of Business Teaches innovation management, supply chain management and project management. She is actively involved in international programs and corporate training in the United States and Europe. She regularly publishes basic and applied research in the areas of project management and supply chain management.