Electronica Medical Media Briefings Wo Notes Final

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Electronica Medical Media Briefings Wo Notes Final

  1. 1. Enabling breakthroughs in medical electronics Electronica 2008 Briefing presentation
  2. 2. Opportunity for impact Consistent market growth over last 25 years, strong trends driving future <ul><li>Aging populations </li></ul><ul><li>By 2020, >1 billion people will be 60+ years </li></ul><ul><li>Rising healthcare costs </li></ul><ul><li>U.S. healthcare spending 16% of GDP </li></ul><ul><li>Costs grow from $2 trillion in 2007 to $3.1 trillion in 2012 </li></ul><ul><li>Remote and emerging markets </li></ul><ul><li>China healthcare expenditure increased 277% from 2006 to 2007 </li></ul><ul><li>Personal healthcare </li></ul><ul><li>38% of medical semiconductor revenue in 2007 went into consumer medical devices </li></ul>Medical Devices and Supplies Market $B CAGR: 1979-2007 = 10% Source: MDDI, Databeans, National Coalition on Health Care, TI 1979 1981 1983 1985 1987 1989 1991 1993 1995 1997 1999 2001 2003 2005 2007
  3. 3. Diagnostic, patient monitoring and therapy Diverse and broad opportunity Consumer medical devices Medical imaging Medical instruments <ul><li>Digital thermometers </li></ul><ul><li>Blood glucose monitor </li></ul><ul><li>Blood pressure monitor </li></ul><ul><li>Insulin pumps </li></ul><ul><li>Heart rate monitors </li></ul><ul><li>Audiology (digital hearing aids) </li></ul><ul><li>Ultrasound </li></ul><ul><li>CT </li></ul><ul><li>MRI </li></ul><ul><li>X-Ray </li></ul><ul><li>Other imaging (nuclear, positron emission tomography) </li></ul><ul><li>ECG </li></ul><ul><li>EEG </li></ul><ul><li>Blood oxygen (pulse oximeter) </li></ul><ul><li>Blood pressure </li></ul><ul><li>Temperature </li></ul><ul><li>Ventilation/ respiration </li></ul><ul><li>Defibrillators </li></ul><ul><li>Implantable devices </li></ul><ul><li>Laboratory equipment </li></ul><ul><li>Dialysis machines </li></ul><ul><li>Analytical instruments </li></ul><ul><li>Surgical instruments </li></ul><ul><li>Dental instruments </li></ul>2007 Medical Semiconductor Market $2.65B $1B 12% CAGR $500M 11% CAGR $450M 13% CAGR $700M 11% CAGR Source: Databeans Medical 2007 (CAGR 2004 – 2012), Incube Labs
  4. 4. TI Medical offering <ul><li>Broad analog and digital catalog portfolio </li></ul><ul><li>Application- specific products </li></ul><ul><li>TI investments </li></ul><ul><li>Dedicated resources </li></ul><ul><li>University research </li></ul><ul><li>VC investment </li></ul><ul><li>New technologies </li></ul><ul><li>Implantables </li></ul>Implantable Bluetooth ® ULP ???? Quality & reliability Process technology Sales & applications support Bluetooth ®
  5. 5. Health care revolution Broadest portfolio of analog and embedded processing solutions in the market
  6. 6. Medical imaging modalities MRI Hyperspectral Imaging 3D/4D imagers Ultrasound PET / CT / OCT Digital X-ray Vein viewer
  7. 7. Complete IC portfolio for medical imaging *high-performance DSPs include multi-core, single-core and floating point <ul><li>High-perfor-mance DSPs </li></ul><ul><li>Digital signal controllers </li></ul><ul><li>High-perfor-mance DSPs </li></ul><ul><li>Digital signal controllers </li></ul><ul><li>High-perfor-mance DSPs </li></ul><ul><li>Digital signal controllers </li></ul><ul><li>High-perfor-mance DSPs </li></ul><ul><li>DaVinci ™ -based SoCs </li></ul><ul><li>Low power OMAP35x application processors </li></ul><ul><li>High-perfor-mance DSPs* </li></ul><ul><li>Digital signal controllers </li></ul>Embedded processors PET X-ray MRI Ultrasound CT Power management, data converters, amplifiers, clocks, interfaces, switches Catalog Analog <ul><li>Amplifiers </li></ul><ul><li>Analog front ends </li></ul><ul><li>Data converters </li></ul><ul><li>Analog front ends </li></ul><ul><li>Pulsers and switches </li></ul><ul><li>Analog front ends </li></ul><ul><li>Data converters </li></ul>Application-specific Analog products
  8. 8. Embedded processors for medical imaging <ul><li>Optimal imaging capabilities & system performance </li></ul>High performance fixed & floating point DSPs Digital signal controllers DaVinci ™ System On Chips (SOCs) Highest performance multi- core/singlecore with low power OMAP35x Applications processors Enabling portability Improving overall system functionality F2810 F2808 F28105 F2812 C6745 C6452 C6474 C6747 C6455 C6415 OMAP3530 OMAP3515 OMAP3525 OMAP3505 DM644x DM6437 DM648 DM6467 DM355
  9. 9. High performance benefits <ul><li>Processor performance speeds image analysis – faster, clearer results </li></ul><ul><li>New algorithms offer the latest image processing techniques – adaptive, patient-specific diagnostics </li></ul><ul><li>Programmable DSPs enable software upgrades – lengthening the life of imaging equipment </li></ul>
  10. 10. Portability benefits <ul><li>High performance/low power processors enable portability – bringing imaging equipment to the point of care </li></ul><ul><li>Integrating functions and reducing board size equals smaller equipment – OEMs can support fixed, cart, portable, and handheld product lines </li></ul><ul><li>Reduced boot times/processing times delivers faster results – directly impacting trauma, triage, and remote care </li></ul>
  11. 11. Enabling new applications <ul><li>DSPs meet real-time processing requirements for 3D/4D – delivering clinically significant results </li></ul><ul><li>New applications such as optical coherence tomography benefit from computationally intensive DSP performance </li></ul><ul><li>Inherent processor flexibility supports new algorithms for patient-specific tissue elasticity images </li></ul><ul><li>Low power enables imaging to go to the patient – regardless of location </li></ul>3D/4D Ultrasound Optical Coherence Tomography
  12. 12. Ecosystem speeds development Third party network eases development, qualification and time to market concerns
  13. 13. Ultrasound / medical imaging <ul><li>Benefits: </li></ul><ul><li>Portable </li></ul><ul><li>Higher resolution, better clarity </li></ul><ul><li>More affordable </li></ul><ul><li>Faster scans, faster boot-time </li></ul><ul><li>Less invasive </li></ul><ul><li>Instant diagnostics </li></ul>
  14. 14. System level benefits for ultrasound Transmit Beamformer Front End Back End Mid Receive Beamformer Beamformer Control Unit Preprocessing Spectral Doppler Processing B Mode Processing Color/Power Doppler Processing Scan Conversion Post Processing Clocking LPW RS232 USB 1394 802.11 Common Interfaces Power Plug AC Line AC/DC Supply With Green Mode Controller Main Power Supply Backlight Touchscreen System Power Supply Voltage Super. Memory Interfaces MMC/SDIO IDE/ATA Ultrasound OS/UI CW (analog) Beamformer Tx Buffer Amp Passive LPF FET Driver Embedded Processing ADC DAC Audio Amp ADC Analog Front End LNA VCA Low Pass Filter PGA Amp + Filter Amp Stage T/R Switches HV MUX Transducer
  15. 15. System level benefits for ultrasound Transmit Beamformer Front End Back End Mid Receive Beamformer Beamformer Control Unit Preprocessing Spectral Doppler Processing B Mode Processing Color/Power Doppler Processing Scan Conversion Post Processing Clocking LPW RS232 USB 1394 802.11 Common interfaces Power Plug AC Line AC/DC Supply With Green Mode Controller Main Power Supply Backlight Touchscreen System Power Supply Voltage Super. Memory interfaces MMC/SDIO IDE/ATA Ultrasound OS/UI CW (analog) Beamformer Tx Buffer Amp Passive LPF FET Driver Embedded processing ADC DAC Front end Back end Audio Amp Mid ADC Analog Front End LNA VCA Low Pass Filter PGA Amp + Filter Amp Stage T/R Switches HV MUX Transducer Analog signal chain High-PerformanceDSP High- PerformanceDSP UCCxx DSP SoC/Apps. processor TPAxx High- PerformanceDSP ADS16xx Interface CDC TPSxx
  16. 16. AFE58xx family for ultrasound systems 256 1024- System Channels Mid-Range Time Portable 512 32 Premium & High-End Portable High End 16 Ultra-portable/Handheld Ultra Portable Future 64 128 Mid Range Production Sampling AFE5804 AFE5851 AFE5801 Next-generation Portable AFE58xx Next-generation high end AFE5805
  17. 17. AFE5804/05 differentiating features <ul><ul><li>Fast ADC overload recovery for rugged performance </li></ul></ul><ul><ul><li>Optimized process technology: </li></ul></ul><ul><ul><li>VCA = SiGe BiCom 3 </li></ul></ul><ul><ul><li>ADC= CMOS C05 </li></ul></ul>Enables portability with 50% smaller size TI Solution Competition 15mm 16mm 9mm 16mm
  18. 18. AFE5851/01 for handheld ultrasound Reference 16- or 8-channel, over 40% lower power, 70% smaller size than closest competitor ADC VCA/ PGA 16 Ch Logic/controls IN1 : : IN16 LVDS OUT SPI Clamp & LPF <ul><li>New architecture enables new system partitioning where customers have their own or no low noise amplifier (LNA) </li></ul><ul><li>Digital gain control removes external DAC for smaller footprint and minimized noise </li></ul><ul><li>New VCA architecture improves SNR for large input signals </li></ul>Ultra-portable/Handheld
  19. 19. Evolution to portability 15mm 9mm 15mm 9mm 9mm 9mm 9mm 9mm 135-pin, 15*9 mm 1.23 nV/rtHz 101 mW/Ch @ 40MSPS AFE5804 64-pin, 9*9mm 64-pin, 9*9mm 135-pin, 15*9 mm 5.0 nV/rtHz (without LNA) 5.0 nV/rtHz (without LNA) 0.85 nV/rtHz 58 mW/Ch @ 50 MSPS 39 mW/Ch @ 32.5 MSPS 122 mW/Ch @ 40 MSPS AFE5801 AFE5851 AFE5805
  20. 20. Availability & pricing www.ti.com /ultrasound October 2008 October 2008 Available now Available now EVM $52 ea. @ 1ku $92 ea. @ 1ku $58 ea. @ 1ku $56 ea. @ 1ku Price March 2009 December 2008 September 2008 July 2008 Production October 2008 October 2008 Available now Available now Samples AFE5801 AFE5851 AFE5804 AFE5805
  21. 21. System level benefits for ultrasound Transmit Beamformer Front End Back End Mid Receive Beamformer Beamformer Control Unit Preprocessing Spectral Doppler Processing B Mode Processing Color/Power Doppler Processing Scan Conversion Post Processing Clocking LPW RS232 USB 1394 802.11 Common interfaces Power Plug AC Line AC/DC Supply With Green Mode Controller Main Power Supply Backlight Touchscreen System Power Supply Voltage Super. Memory interfaces MMC/SDIO IDE/ATA Ultrasound OS/UI CW (analog) Beamformer Tx Buffer Amp Passive LPF FET Driver Embedded processing ADC DAC Front end Back end Audio Amp Mid ADC Analog Front End LNA VCA Low Pass Filter PGA Amp + Filter Amp Stage T/R Switches HV MUX Transducer Analog signal chain High-PerformanceDSP High- PerformanceDSP UCCxx DSP SoC/Apps. processor TPAxx High- PerformanceDSP ADS16xx Interface CDC TPSxx
  22. 22. TX734: Quad-channel high-voltage pulser <ul><li>Saves 50% board space vs. discrete </li></ul><ul><li>Active Damping for better image quality </li></ul><ul><li>Tailored for portable to mid-range ultrasound systems </li></ul>9mm 9mm 3-level FET-output CH1 Active Damping Logic, Level Translator & Driver 3-level FET-output CH1 Active Damping Logic, Level Translator & Driver 3-level FET-output CH1 Active Damping Logic, Level Translator & Driver 3-level FET-output CH1 Active Damping Logic, Level Translator & Driver
  23. 23. Active damping for better image quality <ul><li>+/-75V output voltage and peak output current of +/- 2A </li></ul><ul><li>Clean 3-level RTZ waveform </li></ul><ul><li>Improved pulse symmetry </li></ul><ul><li>Low 2nd order distortion of -40dB </li></ul>70 60 50 40 30 20 10 0.0 -10 -20 -30 -40 -50 -60 -70 Output Voltage (V) 1.4u 1.6u 1.8u 2.0u Time (s) 2.2u 2.4u 2.6u TX734 Output Characteristics at 5 MHz Damping Effect
  24. 24. TX734 availability and pricing <ul><li>TX734: Samples Jan 09 Production 4Q09 Pricing $10 </li></ul><ul><li>@ 1K unit </li></ul>9mm TX734 9mm EVM available Feb 09
  25. 25. Reduce wires for patient comfort <ul><li>Three electrodes on head </li></ul><ul><li>Two electrodes on forehead </li></ul><ul><li>One electrode next to each eye </li></ul><ul><li>Two electrodes under mouth </li></ul><ul><li>Two electrodes on each leg </li></ul><ul><li>A pulse oximeter on the finger </li></ul><ul><li>A chest belt for respiration monitor </li></ul><ul><li>A breathing tube </li></ul><ul><li>… all collected on the blue box </li></ul><ul><li>From the blue box, a very thick cable ran to the computer that collected all the signals </li></ul>Now go to sleep …
  26. 26. New products and paradigms emerging <ul><li>Body worn monitoring devices Chip + Sensor + printed battery in a low cost DISPOSABLE package </li></ul><ul><ul><ul><li>Real time </li></ul></ul></ul><ul><ul><ul><li>Intelligent </li></ul></ul></ul><ul><ul><ul><li>Continuous </li></ul></ul></ul><ul><ul><ul><li>Wireless </li></ul></ul></ul>For in-hospital and out-of-hospital continuous wireless monitoring of vital signs and other physiological data directly off the body Patient monitor EVOLUTION Wireless portable patient monitor ECG / Heart rate Temperature REVOLUTION Respiration Location Activity / Motion Smart Bandage
  27. 27. Corporate pilots for health and wellness OMAP ™ LoCosto ™ Chronic Disease Management GSM/GPRS Bluetooth / ULP Bluetooth / ULP Zigbee / 802.15.4 Weight scale Blood pressure monitor Smart bandage Vital Signs Monitoring 800 MHz / 900 MHz ISM 2.4GHz ISM (Zigbee/BT/ 802.15.4/ULP) Weight Management
  28. 28. Electronics inside the human body Deep brain stimulation Cochlear implant Gastric pacemaker Neuro- stimulator Implantable devices Retinal implant
  29. 29. Semiconductors impact 1980s 1990s 2000 and beyond Computing transformed Communications transformed Healthcare transformed Computing revolution Communications revolution Healthcare revolution
  30. 30. Thank You
  31. 31. AFE58xx family parameters 16 8 No. of Channels 2.5 to 32.5 MSPS 1 Vpp VCA+LPF+ADC LNA+VCA+LPF+ADC Integration 1 2.5 MHz and 1 7M Hz, 2 nd order 280 mVpp 0.75 nV/rtHz 1.23 nV/rtHz TGC: 1 01 mW/ch ( 40MSPS ) CW: 65 mW/Ch AFE580 4 30dB/ 36dB N/A 2 Vpp N/A N/A 5.0 nV/rtHz TGC: 58mW/ch ( 50MSPS ) CW: N/A AFE5801 8x5 + polarity 10 to 50 MSPS -65dB FS 10MHz and 15MHz, 2 nd order 20, 25, 27, 30 dB 50dB/ 46d B Fixed: 20dB 250 mVpp 1.1 nV/rtHz 0.75 nV/rtHz 0.85 nV/rtHz TGC: 122mW/ch ( 40MSPS ) CW: 74 mW/Ch AFE580 5 N/A 5 to 65 MSPS -56dBFS 10MHz, 14MHz and 20 MHz, 2 nd order N/A TGC: 39mW/ch ( 32.5MSPS ) CW: N/A AFE5851 HD2 (5MHz, -1dBFS) ADC clock CW Low-pass Filter LNA (RTI) [nV/rtHz] LNA gain PGA gain Total Gain/ Attenuator range Input Range Noise, CW (RTI) [nV/rtHz] Power Noise (full chain) [nV/rtHz]
  32. 32. HD2=-40dBc Damping Effect Active damping for better image quality Harmonics (dB) 70 60 50 40 30 20 10 0.0 -10 -20 -30 -40 -50 -60 -70 Output Voltage (V) V(Output) 24.0u Time (s) 25.0u 26.0u 10 0.0 -10 -20 -30 -40 -50 -60 Frequency (Hz) 0.0 5.0M 10M 15M 20M

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