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Grant review application.doc 102.912 KB (102912 bytes)

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Grant review application.doc 102.912 KB (102912 bytes)

  1. 1. SNO Grant Review Instructions Eligibility and format: 1- Investigator is a member of SNO and is within first five years of first faculty appointment. 2- The application represents the investigators first application for a national peer reviewed grant (RO1, R21, K award or equivalent) 3- Review request should be at least 10 weeks prior to grant submission deadline. 4- Total application (Abstract + Specific Aims) is limited to under two pages and also should include a NIH formatted biosketch. 5- Two reviewers, who may remain anonymous to maintain confidentiality of the application reviewed, will be selected from the four suggested in the space below by the applicant. Reviewers may choose to contact the investigator at their discretion. 6- Attempt will be made to have the review undertaken by two reviewers within 2 weeks. 7- The review is meant to be an initial feedback based on the Specific Aims. Applicants are highly encouraged to undertake a detailed review of the entire application. 8- Investigator will provide feedback of the SNO review process and application outcome Please complete and return this document to: linda@soc-neuro-onc.org SNO Research/Clinical Trial Review 1 Society for Neuro-Oncology
  2. 2. SNO Grant Review Application Form Name/Designation/Affiliation: Address/Phone/Fax/E-mail: Agency applied to/type/# of yrs/due date: Collaborators and role (1-sentence each): SNO Research/Clinical Trial Review 2
  3. 3. Abstract (300 words or less) SNO Research/Clinical Trial Review 3
  4. 4. Specific Aims (information must not exceed space provided below) SNO Research/Clinical Trial Review 4 Rational and Preliminary Data Experimental Methods
  5. 5. Preferred reviewers (select up to four from the list below and list in order of preference) BASIC SCIENCE Michael Berens Ph.D. Translational Genomics Research Institute Genomics, invasion, preclinical models, profile-guided therapeutics Oliver Bogler Ph.D. M. D. Anderson Cancer Center Signal transduction, cell death, proteomics, cytotoxic agents, animal models Shi-Yuan Cheng Ph.D. University of Pittsburgh Hillman Cancer Institute Invasion, angiogenesis, signaling transduction. Charles Cobbs M.D. University of California San Francisco Clinical:surgical, lab: tumor stem cells, RTK oncogenesis, signaling, viral oncogenesis Waldemar Debinski M.D., Ph.D. Wake Forest University Molecular targeting, experimental therapeutics, tumor progression/maintenance, pre-clinical models Juan Fueyo M.D. University of Texas MD Anderson Cancer Center Gene therapy, cancer stem cells, cell cycle, autophagy Frank Furnari Ph.D. Ludwig Institute Glioma, signal transduction, EGFR, PTEN Saikh Haque Ph.D. Cleveland Clinic Foundation Lerner Research Institute Cell survival/apoptosis, Cytokine- and growth factor signaling mechanisms, brain tumor stem cells, and angiogenesis Isa Hussaini Ph.D. University of Virginia Cellular and molecular biology of astrocytoma (Invasion,Cell Proliferation,Apoptosis, small molecule inhibitors and animal models) Mark Israel M.D. Dartmouth-Hitchcock Medical Center Genomics, oncogenesis (oncogenes /tumor suppressor gene), animal modeling, angiogenesis, preclinical therapeutics, metabolism, biomarkers, protein/protein interactions Martin Jadus Immunotherapy, angiogenesis, macrophage biology, M-CSF C. David James Ph.D. University of California, San Francisco Animal model therapeutic investigations, genomics, molecular and tumor biology of receptor tyrosine kinases Robert Jenkins M.D., Ph.D. Mayo Clinic Genetics, biomarkers, oligodendrogliomas Carol Kruse Ph.D. Sidney Kimmel Cancer Center Primary malignant brain tumors, gliomas, astrocytomas, immunotherapy, cellular therapy, gene therapy, suicide or cytokine gene therapy SNO Research/Clinical Trial Review 5 1. 2. 3. 4.
  6. 6. Catherine Nutt Ph.D. Massachusetts General Hospital Expression profiling, molecular genetics Hideho Okada M.D., Ph.D. University of Pittsburgh Cancer Institute Immunology, immunotherapy, T lymphocyte, dendritic cell, cancer vaccines Russell Pieper Ph.D. University of California San Francisco Cell Signalling, drug resistance, cell cycle control Sandra Rempel Ph.D. Henry Ford Hospital Invasion, ECM-tumor interactions, gliomas, meningiomas Gregory Riggins M.D., Ph.D. Johns Hopkins University Genomics, drug screens, stem cellls, kinases Charles Stiles Ph.D. Neural stem cells, glioma stem cells, transcription factors, signal transduction Erwin Van Meir Ph.D. Emory University Winship Cancer Center Angiogenesis, hypoxia, HIF, drug discovery, oncolytic viruses, p53, pathway, tumor suppressor Robert Wechsler-Reya Ph.D. Duke University Medical Center Medulloblastoma, mouse models, hedgehog, cerebellum EPIDEMIOLOGY Bondy Melissa L. Ph.D. M. D. Anderson Cancer Center Covering a wide range of areas that includes molecular and genetic epidemiology NEURO-ONCOLOGY Susan Chang M.D. University of California San Francisco Clinical research: medical issues Lisa DeAngelis M.D. Memorial Sloan-Kettering Cancer Center Clinical research: chemotherapy, clinical trials, medical issues Henry Friedman M.D. Duke University Medical Center Clinical research: medical issues Amar Gajjar M.D. St. Jude Children's Research Hospital Clinical research: clinical trials, medulloblastoma, late effects, molecular targeted therapies, pediatric neuro-oncology Evanthia Galanis M.D. Mayo Clinic Targeted therapies, virotherapy/gene therapy Mark Gilbert M.D. University of Texas MD Anderson Cancer Center Clinical and translational research, adult, primary brain tumors, chemotherapy, clinical trials Richard Gilbertson M.D., Ph.D. St. Jude Children's Research Hospital Clinical research: pediatric neuro-oncology, early clinical trials, prognostic and correlative markers. Laboratory Research: Genomics, cancer stem cell biology, mouse models Stuart Grossman M.D. Johns Hopkins University Clinical trials, new drug development SNO Research/Clinical Trial Review 6
  7. 7. David Gutmann M.D., Ph.D. Washington University School of Medicine Genetically-engineered mice, preclinical models, signaling pathways, tumor microenvironment Kurt Jaeckle, M.D. Mayo Clinic Clinical Research: medical oncology, gliomas, meningiomas,etc. Also any area involving metastatic CNS disease Mark Kieran M.D., Ph.D. Dana-Farber Cancer Institute Clinical research: pediatric,antiangiogenesis therapies in brain tumors John Laterra M.D., Ph.D Johns Hopkins University School of Medicine Clinical research: medical, targeted therapeutics. Laboratory research: cell signaling, cell death, cancer stem cells, angiogenesis, blood-brain barrier Tobey MacDonald M.D. Children's National Medical Center Clinical research: pediatric neuro-oncology; Laboratory Research: Signal transduction, metastasis, angiogenesis Tom Mikkelsen M.D. Henry Ford Hospital Hermelin Brain Tumor Center Clinical Research: Medical, molecular therapeutics, clinical trials, chemotherapy, neuroimaging. Laboratory Research: Invasion, pre- clinical therapeutics, neuroimaging, animal models Brian O'Neill M.D. Mayo Clinic Primary CNS lymphoma, clinical interventions (e.g. neuroprotection), imaging Michael Prados M.D. University of California San Francisco Clinical research, phase-1 and pilot phase-2 Lawrence Recht M.D. Stanford University Medical Center Clinical or experimental Jeremy Rich M.D. Duke University Medical Center Cancer stem cells, Targeted therapies, Signal transduction, Invasion, Angiogenesis David Schiff M.D. University of Virginia Health Science Center Clinical trials, chemotherapy, treatment-related toxicity, low-grade gliomas, glioblastoma, and PCNSL Clinton Stewart Pharm.D. St. Jude Children's Research Hospital Neurooncology pharmacy. Clinical research: clinical pharmacology, drug development, developmental therapeutics, pharmacokinetics, pharmacogenomics, pediatric CNS tumors. Laboratory research: CNS drug penetration, pharmacokinetics, models, ABC transporters, multidrug resistance Patrick Wen M.D. Dana Farber Cancer Institute Clinical research: medical, novel therapeutics, clinical trials Cynthia Wetmore M.D., Ph.D. Mayo Clinic Clinical research: pediatric brain tumors, cancer predisposition syndromes. Basic research: mouse models, neural stem cells, tumor stem cells, sonic hedgehog, DNA damage NEUROPATHOLOGY Kenneth Aldape M.D. University of Texas M.D. Anderson Cancer Center Clinical research: pathology. Laboratory research: genomics, molecular correlates, profiling Daniel Brat M.D., Ph.D. Emory University School of Medicine Angiogenesis, genetic, pathology SNO Research/Clinical Trial Review 7
  8. 8. Gregory Fuller M.D., Ph.D. University of Texas MD Anderson Cancer Center Clinical research: neuropathology Candece Gladson M.D. University of Alabama at Birmingham Clinical research: pathology. Laboratory research (Invasion, Angiogenesis and models) Roger McLendon M.D. Duke University Medical Center Clinical Research: prognostic markers; therapeutic sensitivity markers. Laboratory research: biorepository, epidemiology, translational research leading to markers of phenotype, prognosis and therapeutic sensitivity Burt Nabors M.D. University of Alabama at Birmingham Clinical research: neuropathology NEUROPSYCHOLOGY Christina A. Meyers Ph.D. University of Texas MD Anderson Cancer Center Cognitive rehabilitation, quality of life, neurotoxicity NEUROSURGERY Mitchel S. Berger M.D. University of California San Francisco Clinical research Peter McL. Black M.D., Ph.D. Brigham & Women's Hospital Clinical research surgery Henry Brem M.D., FACS Johns Hopkins University School of Medicine Drug delivery to the brain, angiogenesis, immunotherapy Thomas C. Chen M.D., Ph.D. University of Southern California Invasion. Basic science: angiogenesis, ER stress, glioma models, gene therapy E. Antonio Chiocca M.D., Ph.D. Ohio State University Medical Center Clinical research: surgery. Lab research: gene and virus-based therapy, invasion Daniel W. Fults M.D. University of Utah Mouse models of brain tumors, signal transduction biology, molecular genetics Robert G. Grossman M.D. The Methodist Hospital Stereotactic surgery, clinical trials Abhijit Guha M.D., FRCS(C) Western Hospital, University of Toronto Transgenic models, angiogenesis, tumor microenvironment, signal transduction, peripheral nerve tumors-surgery and molecular biology Frederick F. Lang M.D. M. D. Anderson Cancer Center Clinical research: surgical therapies. Basic research: developmental therapeutics, gene and viral therapy, stem cells and stem cell therapy Linda M. Liau M.D., Ph.D. University of California Los Angeles School of Medicine Clinical research: surgical, brain mapping, clinical trials. Laboratory research: genomics, immunotherapy, animal models SNO Research/Clinical Trial Review 8
  9. 9. Donald M. O'Rourke M.D. University of Pennsylvania Glioma cell signaling (EGFR, PI3K, etc), experimental therapeutics, surgical therapies, imaging Andrew Parsa M.D. University of California at San Francisco Clinical research: brain tumor surgery James T. Rutka M.D., Ph.D. Hospital for Sick Children Clinical research: brain tumor surgery, pediatric neurosurgery, medulloblastoma, ependymoma, astrocytoma John H. Sampson M.D., Ph.D. Duke University Medical Center Immunotherapy and drug delivery Raymond E. Sawaya M.D. University of Texas MD Anderson Cancer Center Clinical research: surgery/radiosurgery, gliomas and metastasis Daniel Lance Silbergeld M.D. University of Washington Laboratory research: motility and invasion RADIATION-ONCOLOGY Walter Curran, M.D. Thomas Jefferson University Hospital Clinical research: radiation oncology John B. Fiveash M.D. University of Alabama Clinical research: radiation therapy, metastases, glioma. Laboratory research: apoptosis, antibody, radiopharmaceuticals Daphne A. Haas-Kogan M.D. University of California San Francisco Clinical research: radiation, pediatrics, brain tumors. Laboratory research: PI3-kinase signaling, histone deacetylase inhibitors, radiation Minesh P. Mehta M.D. University of Wisconsin-Madison Medical School Clinical trials Jann N. Sarkaria M.D. Mayo Clinic Clinical research: radiation oncology and novel therapeutics. Laboratory research: novel therapeutics, PET imaging, radiobiology, animal models Edward G. Shaw M.D. Wake Forest University School of Medicine Clinical research: radiation therapy, quality of life, adult or pediatric proposals Please complete and return this document to: linda@soc-neuro-onc.org SNO Research/Clinical Trial Review 9
  10. 10. Donald M. O'Rourke M.D. University of Pennsylvania Glioma cell signaling (EGFR, PI3K, etc), experimental therapeutics, surgical therapies, imaging Andrew Parsa M.D. University of California at San Francisco Clinical research: brain tumor surgery James T. Rutka M.D., Ph.D. Hospital for Sick Children Clinical research: brain tumor surgery, pediatric neurosurgery, medulloblastoma, ependymoma, astrocytoma John H. Sampson M.D., Ph.D. Duke University Medical Center Immunotherapy and drug delivery Raymond E. Sawaya M.D. University of Texas MD Anderson Cancer Center Clinical research: surgery/radiosurgery, gliomas and metastasis Daniel Lance Silbergeld M.D. University of Washington Laboratory research: motility and invasion RADIATION-ONCOLOGY Walter Curran, M.D. Thomas Jefferson University Hospital Clinical research: radiation oncology John B. Fiveash M.D. University of Alabama Clinical research: radiation therapy, metastases, glioma. Laboratory research: apoptosis, antibody, radiopharmaceuticals Daphne A. Haas-Kogan M.D. University of California San Francisco Clinical research: radiation, pediatrics, brain tumors. Laboratory research: PI3-kinase signaling, histone deacetylase inhibitors, radiation Minesh P. Mehta M.D. University of Wisconsin-Madison Medical School Clinical trials Jann N. Sarkaria M.D. Mayo Clinic Clinical research: radiation oncology and novel therapeutics. Laboratory research: novel therapeutics, PET imaging, radiobiology, animal models Edward G. Shaw M.D. Wake Forest University School of Medicine Clinical research: radiation therapy, quality of life, adult or pediatric proposals Please complete and return this document to: linda@soc-neuro-onc.org SNO Research/Clinical Trial Review 9

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