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Conceptual study of        Mootravaha Srotas            Prof. Dr. K. Shiva Rama Prasad              M.D (KC), M.A. Ph.D. (...
Doctor …               I am passing more urine more time what to do?               I am getting abdominal bloat and not pa...
Natures existence survival phenomenon     checks the beings nutrient input and     waste material output forms very well  ...
The human body contains trillions of cells  bathed in extra-cellular fluid.  Cells in the body make mess and  generate pil...
Mootra (Urine )                            The Water of Life    Urine is liquid waste produced by an    animals kidney. It...
There was a King “Tymore” –                            once he went to forest for                            hunting. Ther...
But for us the excessive or less use of the system both are problematic.The history of drinking  urine for therapeutic   p...
Urine for Mouth wash, Cure for   Jaundice and Antiseptic too ..    An 18th century French dentist praised    urine as a va...
Urine is known to contain minute                     amounts of proteins made by the body,                     including m...
Normal functions of the                                Mootravaha srotas        Regulating blood volume and blood        p...
Regulating plasma concentrations of    electrolytes - sodium, potassium, chloride,    and other ions by controlling the   ...
Contributing to the stabilization of blood    pH - by controlling the loss of hydrogen    ions and bicarbonate ions in the...
Four fold function                                         Four fold problem                                         Forms...
glucose in urine, Bed-wetting or cessation ofurine production in cardiovascular shock iscommonMany of the body physiology ...
Sanga - as in MootraghataSira grandhi which indicates the involvementof vascular interventionAll of these are with differe...
What we drain out ?                    Urea.                    Urea is the most abundant                    organic waste...
What we drain out ?                 Creatinine.                 Creatinine is generated in skeletal                 muscle...
Metabolism and excretion of Creatininedoctorksrprasad@gmail.com   01-07-2006       19
What we drain out ?                    Uric acid.                    Uric acid is formed by the                    recycli...
Proteinuriadoctorksrprasad@gmail.com       01-07-2006   21
Factors to be noticed    Vasti in terms of Mootravaha srotas is a    Sadyahpranahara Marma    Exercises (Vyayama) and sex ...
EFFECTS OF NEPHRON LOSS ON RENAL    EXCRETORY MECHANISMS    The volume of urine excreted (averaging 1.5 L/d    or roughly ...
Biologic Consequences of Sustained Reductions    in GFR    Although nephron loss can proceed, to some    extent, without e...
EFFECTS OF NEPHRON LOSS ON WATER  REABSORPTION IN SURVIVING NEPHRONS    TUBULE TRANSPORT OF PHOSPHATE    WITH NORMAL AND R...
Transport functions of the various anatomic segments doctorksrprasad@gmail.com   01-07-2006          26
Absorption, metabolism, and excretion of ureadoctorksrprasad@gmail.com   01-07-2006                27
Rhabdomyolysis is - An acute, fulminating,   potentially fatal disease of skeletal muscle   that entails destruction of sk...
That’s all folks                     doctorksrprasad@sify.comdoctorksrprasad@gmail.com   01-07-2006                    29
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Mootravaha ksr

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Mootravaha ksr

  1. 1. Conceptual study of Mootravaha Srotas Prof. Dr. K. Shiva Rama Prasad M.D (KC), M.A. Ph.D. (Jyo)doctorksrprasad@gmail.com 01-07-2006 2
  2. 2. Doctor … I am passing more urine more time what to do? I am getting abdominal bloat and not passing urine what to do? I am getting lots of burning sensation while passing urine, help me. My urine is green in colour. Is it a disease? I get the sensation but not able to pass urine, what to do? All these questions are common for practitioner. What to do? How to understand these problems? What is the natures mystery behind it?doctorksrprasad@gmail.com 01-07-2006 3
  3. 3. Natures existence survival phenomenon checks the beings nutrient input and waste material output forms very well before to the birth in the womb. Out of many - first one is dependent upon the water which is a major part of the life existence. We can not think the life with out water inside body and out side in the world.doctorksrprasad@gmail.com 01-07-2006 4
  4. 4. The human body contains trillions of cells bathed in extra-cellular fluid. Cells in the body make mess and generate piles of garbage. Most of the organic waste products are removed and excreted by the urinary system, discussed and focused in this symposia. The water drains the waste from the body as URINE and the system concerned to it is Mootravaha srotas.doctorksrprasad@gmail.com 01-07-2006 5
  5. 5. Mootra (Urine ) The Water of Life Urine is liquid waste produced by an animals kidney. It is used to extract wastes from the body in liquid form. Urine can also play a role in animal behavior. urine - waste fluid secreted by the kidneys and discharged from the bladder. Medically speaking - The fluid and dissolved substances excreted by the kidney.doctorksrprasad@gmail.com 01-07-2006 6
  6. 6. There was a King “Tymore” – once he went to forest for hunting. There he miss the road and only the clone is behind him. He was thirsty. He wants the water. Some how the clone get the water and asked the king – dear sir, what you can pay for this water, king replied half of my kingdom. OK, if this water doesn’t come out, then? The king replied as usual half of my kingdom. Then the clone said to king – is it not ridiculous to fight such sort of kingdoms.doctorksrprasad@gmail.com 01-07-2006 7
  7. 7. But for us the excessive or less use of the system both are problematic.The history of drinking urine for therapeutic purposes dates back at least to the Holy Roman Empire when great urinal troths were erected in thepublic squares of eachcity-state for residents to both contribute to, and benefit from. doctorksrprasad@gmail.com 01-07-2006 8
  8. 8. Urine for Mouth wash, Cure for Jaundice and Antiseptic too .. An 18th century French dentist praised urine as a valuable mouthwash. In England during the 1860-70s, the drinking of ones own urine was a common cure for jaundice. In more modern times, the Alaskan Eskimos have used urine as an antiseptic to treat wounds. Not only these but many more uses.doctorksrprasad@gmail.com 01-07-2006 9
  9. 9. Urine is known to contain minute amounts of proteins made by the body, including medically important ones such as growth hormone and insulin. The idea of using and recycling urine is not new, it is practiced in Ayurveda for long time with the precautions. There is a $500-million-a-year market for urine ingredients. Enzymes of America plans to market its first major urine product called urokinase, an enzyme that dissolves blood clots and is used to treat victims of heart attacks.doctorksrprasad@gmail.com 01-07-2006 10
  10. 10. Normal functions of the Mootravaha srotas Regulating blood volume and blood pressure by – (1) adjusting the volume of water lost in the urine, (2) releasing erythropoietin, and (3) releasing renin.doctorksrprasad@gmail.com 01-07-2006 11
  11. 11. Regulating plasma concentrations of electrolytes - sodium, potassium, chloride, and other ions by controlling the quantities lost in the urine and controlling calcium ion levels by the synthesis of calcitriol.doctorksrprasad@gmail.com 01-07-2006 12
  12. 12. Contributing to the stabilization of blood pH - by controlling the loss of hydrogen ions and bicarbonate ions in the urine. Conserving valuable nutrients by preventing their excretion in the urine while eliminating organic waste products, especially nitrogenous wastes, such as urea and uric acid. Assisting the liver in detoxifying poisons and, during starvation, de-aminating amino acids so that they can be broken down by other tissues.doctorksrprasad@gmail.com 01-07-2006 13
  13. 13. Four fold function Four fold problem Forms of Sroto dusti • Atipravrutti • Apravrutti • Sanga • Sira Granthidoctorksrprasad@gmail.com 01-07-2006 14
  14. 14. glucose in urine, Bed-wetting or cessation ofurine production in cardiovascular shock iscommonMany of the body physiology leads and altersthe urine out put.Atipravrutti – excess urination as in Prameha,Amavata etc.Apravrutti – diminishing urination as inMootrkruchra,doctorksrprasad@gmail.com 01-07-2006 15
  15. 15. Sanga - as in MootraghataSira grandhi which indicates the involvementof vascular interventionAll of these are with different aetiology andeven with different components of diseasemanifestationBut – the common is the tract – Srotas andthe management to the tract along withrectifying pathology is the present task.doctorksrprasad@gmail.com 01-07-2006 16
  16. 16. What we drain out ? Urea. Urea is the most abundant organic waste. We generate roughly 21 g of urea each day. Most of it is produced during the breakdown of amino acids.doctorksrprasad@gmail.com 01-07-2006 17
  17. 17. What we drain out ? Creatinine. Creatinine is generated in skeletal muscle tissue by the breakdown of creatine phosphate, a high-energy compound that plays an important role in muscle contraction (Vata activity?). Our body generates roughly 1.8 g of creatinine each day, and virtually all of it is excreted in the urine.doctorksrprasad@gmail.com 01-07-2006 18
  18. 18. Metabolism and excretion of Creatininedoctorksrprasad@gmail.com 01-07-2006 19
  19. 19. What we drain out ? Uric acid. Uric acid is formed by the recycling of nitrogenous bases (Kapha associations?) from RNA molecules. We produce approximately 480 mg of uric acid each day.doctorksrprasad@gmail.com 01-07-2006 20
  20. 20. Proteinuriadoctorksrprasad@gmail.com 01-07-2006 21
  21. 21. Factors to be noticed Vasti in terms of Mootravaha srotas is a Sadyahpranahara Marma Exercises (Vyayama) and sex act (Prasanga) – Vata activity disturbs the KUB systems Liquids such as Madya (alcohol) and jala sevana (water consumption) of Kapha concerns also vitiates the srotas Vegadharana enhances (inhibited neural reflexes) the Vata (Apanavata) is the prime factor to vitiate the Mootravaha srotas We can not deny in some of the occasions even the role of Ca+ ion or other electrolytes.doctorksrprasad@gmail.com 01-07-2006 22
  22. 22. EFFECTS OF NEPHRON LOSS ON RENAL EXCRETORY MECHANISMS The volume of urine excreted (averaging 1.5 L/d or roughly 1 mL/min) represents the sum of two large, directionally opposite processes¾namely, ultrafiltration of 180 L/d or more of plasma water (or 125 mL/min) and reabsorption of more than 99% of this filtrate by transport processes in the renal tubules. While renal blood flow accounts for about 20% of resting cardiac output, the kidneys comprise only about 1% of total body weight. This disproportionate allocation of cardiac output, greatly exceeding blood flow per gram of brain, heart or liver, is required for the process of ultrafiltrationdoctorksrprasad@gmail.com 01-07-2006 23
  23. 23. Biologic Consequences of Sustained Reductions in GFR Although nephron loss can proceed, to some extent, without equivalent loss of GFR due to the compensatory mechanisms, determination of the total GFR of both kidneys remains the most reliable clinical index of overall excretory function. The effects of impaired GFR are to reduce the total rate of delivery of solute into the glomerular filtrate. When accompanied by comparably reduced rates of urinary excretion, retention and accumulation of the unexcreted solute occurs, resulting in increased concentrations of the substance in the plasma and other body fluids.doctorksrprasad@gmail.com 01-07-2006 24
  24. 24. EFFECTS OF NEPHRON LOSS ON WATER REABSORPTION IN SURVIVING NEPHRONS TUBULE TRANSPORT OF PHOSPHATE WITH NORMAL AND REDUCED NEPHRON MASS Alterations in Vitamin D Metabolism Hyperparathyroidism in Chronic Renal Failure HYDROGEN AND BICARBONATE TRANSPORT WITH NORMAL AND REDUCED RENAL MASS TUBULE POTASSIUM TRANSPORT WITH NORMAL AND REDUCED NEPHRON MASSdoctorksrprasad@gmail.com 01-07-2006 25
  25. 25. Transport functions of the various anatomic segments doctorksrprasad@gmail.com 01-07-2006 26
  26. 26. Absorption, metabolism, and excretion of ureadoctorksrprasad@gmail.com 01-07-2006 27
  27. 27. Rhabdomyolysis is - An acute, fulminating, potentially fatal disease of skeletal muscle that entails destruction of skeletal muscle as evidenced by myoglobinemia and myoglobinuria – which is an excess urination resultant connected to that of the Vata involvement in Mootravaha srotas. Microalbuminuria in patients with diabetes mellitus is a common situation in KUB system. Such conditions are innumerable to be evaluated from observation based Ayurvedic transformed to Evidence based medicine.doctorksrprasad@gmail.com 01-07-2006 28
  28. 28. That’s all folks doctorksrprasad@sify.comdoctorksrprasad@gmail.com 01-07-2006 29

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