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Ksr rs bzap2

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Excellence of Rasaaushadhi In Ayurveda Practice
Dr.KSR Prasad as Resource Person in Rasashastra ROTP at Nori Ramashastry Govt. Ayurveda College, Vijayawada delivered Guest lecture on Excellence of Rasaaushadhi In Ayurveda Practice – Part-1 :: Part-2 and Avaji on December 14 and 15th 2009.

Published in: Health & Medicine, Technology

Ksr rs bzap2

  1. 1. Excellence of Rasaaushadhi In Ayurveda Practice – Part 2 Our Role in Establishment of Rasa-Aushadhi Glory in General Ayurveda PracticeInstead of cursing the darknessTry to lit a small LIGHT –It becomes FLAMEone day to cook your food 1 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  2. 2. స “రస” ైదుయ్లకు అ నందనల ో A Technoayurveda International Presentation In Association with Ayurmitra Technoayurveda.wordpress.com Rasashastra Re-Orientation Program atNRS Govt. Ayurveda College, Vijayawada on 15-12-2009 2
  3. 3. Excellence of Rasaaushadhi In Ayurveda Practice Rasa Aushadhi Common Diseases in GAP Research in RT Dhatuvada - Dehavedha न च रसशास्तर्ं धातुवादाथर्मेवेित मन्तव्यं दे हवेधद्वार मुक्तरे व परम ूयोजनत्वात ् े रसेश्वर दशर्न Conversion of the lower metals to higher isthe job of “Chemistry”. What is expected from “Rasashastra” is tomake is the “Dehavedha” for the body toattain the “Mukti” from “Disease” 3 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  4. 4. Excellence of Rasaaushadhi In Ayurveda Practice Rasa Aushadhi Common Diseases in GAP Research in RT Introduction• Rasashastra a Scientific Chemotherapy of Ayurveda is at Cross-Roads• The influences and advancements of - – “Pharmacy standards” – “Evidence Based Medicine protocols” – A major Global “Toxic concept campaign” and – “Ayurveda Fraternity Deception”• - are making panic to the Ayurveda community in general and Rasashastra (Pharmacy) division in specific. 4 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  5. 5. Excellence of Rasaaushadhi In Ayurveda Practice Rasa Aushadhi Common Diseases in GAP Research in RT Ayurveda in Research• The Excellency to bring back – Research in the any branch especially in Rasashastra is essential.• Ayurveda has many units of Research like – CCRAS, ICMR and many NGOs for making Research and informing the Research fruits to the user. – Whether the Researches in Ayurveda are User demand fulfillments? – Are the Researches followed are up to the International standard to accept Globally our Medicine? – Are we make user to satisfy by the – • “Standard” • “Effect” or • “Free of Toxicity” • By any other way . . . At least . . . 5 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  6. 6. Excellence of Rasaaushadhi In Ayurveda Practice Rasa Aushadhi Common Diseases in GAP Research in RT Need of the Hour• To be frank the researches in Ayurveda are not user friendly and could not reach the ultimate user – General Ayurveda Practitioner• As we are at the Rasashastra researches in concern at present – it is necessary to know how the researches are made in this branch. 6 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  7. 7. Excellence of Rasaaushadhi In Ayurveda Practice Rasa Aushadhi Common Diseases in GAP Research in RT Research in General• Researches are of many folds to obtain the “True Knowledge” – A search again and again to get the perfect knowledge.• Commonly followed are – – 1. Explorative Research • Literary • Experience survey – 2. Conclusive • Descriptive • Experimental 7 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  8. 8. Excellence of Rasaaushadhi In Ayurveda Practice Rasa Aushadhi Common Diseases in GAP Research in RT Research Process• Problem definition• Objectives set: purpose – place – status - means – Research questions – Hypothesis – Boundary of the study• Research design – Sampling – experiment – questioners• Data collection• Data analysis• Interpretation of results – should be with real world problem and conclusion• Validation of results 8 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  9. 9. Excellence of Rasaaushadhi In Ayurveda Practiceushadhi Common Diseases in GAP Research in RT Activity in Research Is Rasa-Medicine is Target oriented? Rasa Parpati Samanya Shodhana Godugdha Parada Gandhaka Ghrita Bharjita Shodhita Gandhaka Samanya Bhringaraja Shodhana with Lime Powder Hingulottha Lashuna + Saindhava Parada Parpati 1 of 2 Parpati 2 of 4Shodhita Parada What Target differences are brought in usage of these combinations and permutations with set of combinations and permutations of Anupana, Sahapana in General Ayurveda Practice 9 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  10. 10. Excellence of Rasaaushadhi In Ayurveda Practiceushadhi Common Diseases in GAP Research in RT Activity in Research Is Rasa-Medicine is Target oriented? A cutting edge technology is the need of hour in Ayurveda. The road beyond Production & Practice should be visualized. Dravya Shodhana Probable? Parada Hingulotha (Alimentary) Pittahara? Lime powder (Ca+)(neural) Vatahara? Lasuna + (Tissue invader) Saindhava Kaphahara? Gandhaka Godugdha Agni? Bhringaraj Panchabhutagni? Whether the “Shodhana” makes the Dravya to reorganize the Chemical bonding? 10 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  11. 11. Excellence of Rasaaushadhi In Ayurveda Practiceushadhi Common Diseases in GAP Research in RT Activity in Research Parpati in Practice Parpati Additives Target Rasa Rasa + Gandhaka Annavaha, Udakavaha (Base combination) Rasavaha, Lasika (Twak) Panchamruta + Loha, Abhraka Annavaha, Pranavaha Tamra Sukravaha Bola + Bola Rakta vaha, Artavavaha Loha + Loha Annavaha, Lasika (Twak) Swarna + Swarna Annavaha, Pranavaha Sukravaha Tamra + Tamra, Annavaha, Mootravaha Vatsanabha Lasika (Twak) Sweta Soraka, Sphatika, Annavaha, Mootravaha Navasara 11 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  12. 12. Excellence of Rasaaushadhi In Ayurveda Practiceushadhi Common Diseases in GAP Research in RT Activity in Research Raw drug collection - Identification Who Answers ? Ingredient Is there any Genotoxicity ? Multiple Bhavana Drug concentrations Shodhana to maintain half life? Marana Pharmaceutical Drug Excretion ? Single / Multiple Multi Drug Target Action? Shodhita combinations Ingredients Multiple Pharmaco- Multiple Preparation dynamics Clinical methods attitudes Anupana Multiple Pharmacokinetics Sahapana Aushadha Kaala 12 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  13. 13. Excellence of Rasaaushadhi In Ayurveda Practiceushadhi Common Diseases in GAP Research in RT Activity in Research Another Example of Kupipakwa Rasayana • In Kupi pakwa Rasayana procedures – the medicine collection is from the “Talastha” or “Kantastha” and “Ubhayastha”. • Taking the example of “Somanatha tamra Bhasma and Malla Sindhura (Tamra sindhura) are from one preparation. – The “Kantastha” – called as Tamra Sidhura acts on STI, Tamaka Swasa – Where as – the “Talastha” collection called as Tamra Bhasma acts on – many diseases, especially on Annvaha, Pranavaha, Twak vikara, etc. • What makes the difference of collection in a process? • Whether the target is to prepare one medicine in a pharmaceutical procedure or two Birds in one shot? • Does such short cut methods are encouraged by the Learned community? 13 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  14. 14. Excellence of Rasaaushadhi In Ayurveda Practiceommon Diseases in GAP Research in RT Activity in Research Research Methods to Adopt What Literary Research? • Literary research in Rasashastra has a wide scope and is the need of the hour. • The print available Rasashastra books are few and the abundance of Manuscripts makes – a chance to explore Rasashastra. • For Eg. – a preparation have many dialects of preparation methods – scrutinizing them makes us to have a target oriented potent Medicine to reach. 14 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  15. 15. Excellence of Rasaaushadhi In Ayurveda Practiceommon Diseases in GAP Research in RT Activity in Research Research Methods to Adopt How to survey in RT • Survey and education of Rasa medicine usage in the practice is recorded – – What is the need for Practitioner? • Symptom target • Disease target • Organ target • System target • Health target – What medicines are causing the adverse effects? – Classified Recordings of - • Hypersensitivity • Hepato toxicity • Nephro toxicity • Neuro toxicity 15 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  16. 16. Excellence of Rasaaushadhi In Ayurveda Practicemmon Diseases in GAP Research in RT Activity in Research Research Methods to Adopt Do we do Descriptive Research in RT • Much of the present day Researches are following the Descriptive Method researches – which are with limited scope - as – • Prospective study – common – Physico / Pharmaco -chemical studies – Drug effect in clinical study • Retrospective study – Reverse pharmacology study - uncommon in Ayurveda 16 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  17. 17. Excellence of Rasaaushadhi In Ayurveda PracticeResearch in RT Activity in Research Research Methods to Adopt Research Models Experimental Research in RT Experimental studies have no pickup in Ayurveda because of non-efficiencies /exposure in maintenance of –  Animal Houses and  Analytical lab. The limping or dependent studies are successful some times but not yielding the full-fledged fruits and results to the Ayurveda community. More systematic animal experiments and lab studies are required as the AYUSH is funding and encouraging for the “Expressive Projects” 17 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  18. 18. Excellence of Rasaaushadhi In Ayurveda PracticeActivity in Research Research Methods to Adopt Research Models Research Models in RT • Best Research model for successful Penetration Rating in to market is through fulfilling the peoples needs – • Mathematical – – Inventory – Parametric – Replacement • Algorithmic – is a well-defined sequence steps to solve a problem – Combinational – Polynomial 18 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  19. 19. Excellence of Rasaaushadhi In Ayurveda PracticeActivity in Research Research Methods to Adopt Research Models Inventory Research • Present day researches seems to validate ancient formulations rather than productivity • No contribution of the “Neo-Rasashastra” is brought forward • An inventory model is – – Classify and visualize the old formula as TLC, HPTC, Finger print technology, etc – Chemical structure is identified – Reconstruct the chains for validation and comparison – Restructure the combination to the needs of user – Rejuvenation of Vedic Chemistry – There by combating the present day dreadful diseases 19 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  20. 20. Excellence of Rasaaushadhi In Ayurveda PracticeActivity in Research Research Methods to Adopt Research Models Parametric Research • A classical design of Research (validation)– mere Chemical constituents – studied with - – Pre-fixed Parameters – Chemical structure evaluated – Limited framework to study • A locality • One medicine • Small duration – Mono-directional – Target based – Result oriented 20 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  21. 21. Excellence of Rasaaushadhi In Ayurveda PracticeActivity in Research Research Methods to Adopt Research Models Replacement Research • In Ayurveda – we are commonly using the substitutes – – Whether the replacements are equivalent? – Does they give exactly results as their substitutes? – we don’t know! • Instead – using Replacement Research is better – here we replace with – – Standard replacement – Equivalent replacement (based on Rasa, Guna, etc) – Omitting replacement – Complete replacement 21 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  22. 22. Excellence of Rasaaushadhi In Ayurveda PracticeResearch Methods to Adopt Research Models GAP in Research Conclusion Combinational Research • The medicines commonly used are of Herbo- mineral combinations • The combinational research in Rasashastra is defined as – – A team of Rasashastra - Chemistry – Botany – Pharmacy – Ayurveda Specialized Branch - are together to work on a compound – unbiased – Various methods of said preparations are compared for the – structure – safety (Toxicity) – economy - efficacy – 22 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  23. 23. Excellence of Rasaaushadhi In Ayurveda PracticeResearch Methods to Adopt Research Models GAP in Research Conclusion Polynomial Research• It is defined as - A mathematical function that is the sum of a number of terms – – As the standards of the Ayurveda are unique and not fit to the “Rest of the World” – • A multi center – large sample – uni-directional studies are invited – This is possible by the universities or CCRAS or ICMR – creating a Nodal officer to control the studies all over – even the PG Centers • A common minimum policy is created to ensure the – Drug Safety – Half life – Target area and – Excretion 23 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  24. 24. Excellence of Rasaaushadhi In Ayurveda PracticeResearch Methods to Adopt Research Models GAP in Research Conclusion Reverse Pathology – Reverse Pharmacology• Reverse pathology in Ayurveda is said as – Samprapti Vighatana• Planning of the Vighatana with the combination is the most important task in Ayurveda Practice. It is possible with the understanding of Ayurveda principles and application of – – Rasa – Guna – Veerya – Vipaka – Prabhava• Reverse Pharmacology is understood under the present day technology about – – Drug Excretion – Drug target – Half life, etc 24 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  25. 25. Excellence of Rasaaushadhi In Ayurveda PracticeResearch Methods to Adopt Research Models GAP in Research Conclusion Example • Madhumeha patho-physiology is – • Bahumootrantaka Ras – Tissues of body are liquidated - used in Madhumeha has – – The sugar reserves undertakes neo- • Ahiphena glucogenesis • Dadima – Non utilization of CHO by muscles or • Kadali even for transformation in to deposits • Parad – Free CHO (Shareera Kleda) mix with • Loha fluids (Ap Dhatu) of the body • Mouktika especially Rakta • Praval – Expresses as “Bahudrava shleshma • Shalmali yukta – Madhurakta” • Udumbara – The liquids mixed with CHO of the • Vanga body are transported to the KUB – termed as - Madhumeha – i.e. Elimination of excess fluids along with Shareera Kleda (Glucose) – The reverse pathology planned on these grounds are – in RED – & – Fluid Regulation – CHO Regulation 25 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  26. 26. Excellence of Rasaaushadhi In Ayurveda PracticeResearch Methods to Adopt Research Models GAP in Research Conclusion Repatriation Hypothesis i.e. Reverse Pathology Fluid RegulationAhiphena paralyzes Same time the Urine re-sigmoid smooth absorption from Henleys loopmussels & Dadima is retarded by Vanga, andprevents the fluid Kadali 2re absorption from - Udumbara makes thecolon by reverse integumentary systemperistalsis, Loha (Lasika) to constrain and fluidrequire maximum retained is drained back tofluid for synthesis systemand absorbs thewater once again –so, the fluid re-entry in to systemis regulated at the 1same time Shalmaliabsorbs the fluid inthe colon 26 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  27. 27. Excellence of Rasaaushadhi In Ayurveda PracticeResearch Methods to Adopt Research Models GAP in Research Conclusion Repatriation Hypothesis i.e. Reverse Pathology CHO Regulation Formation of shareera CHO combustion is done kleda – CHO is through rapid muscle through Liver (Mamsa movements by initiating Khanda) and Acetylcholine at motor Pancreas – there by endplates in muscle fiber the Parada acts as 3 through - Mouktika – agent to and prevents Pravala the neo-glycolysis Heat generated with muscle movement makes the bahudrava shleshma to evaporate 5 4 Shalmali, Parada initiates the pancreas to regulate the CHO 27 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  28. 28. Excellence of Rasaaushadhi In Ayurveda PracticeActivity in Research Research Methods to Adopt Research Models GAP in Research GAP Research Models • General Ayurveda Practitioners Research models are with – – Involved Data base recording and – submission to the nearest center for analysis – as a part of big survey • Suggesting the center for – – epidemic and endemic events and – actively participating in Health campaigns with – Evidence based Research drugs provided by the center in time 28 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  29. 29. Excellence of Rasaaushadhi In Ayurveda PracticeActivity in Research Research Methods to Adopt Research Models GAP in Research GAP Research Models • Area specific diseases are submitted and a common drug therapy modules are adopted as per the centers advise • Center responsibilities - – Periodical CME for the practitioners with in 50 -100 KM diameter – Door to door survey of health / disease conditions – Providing Easy access to the people about pro and cants of drug – Life line access through telephone / Internet in Institutional / Hospital centers – Radio talks / TV shows / FM Radio services organized to create Awareness to the Local people 29 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  30. 30. Excellence of Rasaaushadhi In Ayurveda PracticeResearch Methods to Adopt Research Models GAP in Research Conclusion Responsibilities of Practitioner • Reclassify the usage of Rasaaushadhi in – Infectious – Metabolic – Emergencies, etc • Diseases of attention – AIDS – Cancer – ED – Paralysis • Developing the databank for EB Ay Medicine • Defining the Rasaushadhi in Departmental use – Shalya, Prasuthi, etc. • Suggestion of Contribution required in practice • Ethical practices in Rasa practice 30 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  31. 31. Excellence of Rasaaushadhi In Ayurveda PracticeResearch Methods to Adopt Research Models GAP in Research Conclusion Conclusion• The Interference of too many or• No involvement – is the problem in Ayurveda Research• Developing Teamwork instead & Working Unbiased in the Research and incorporating Rasaaushadhi vividly in General Ayurveda Practice are the solutions for development - because …. –आरोग्यम ् (रस) भाःकरािदच्छे त ् 31 Dr. K. Shiva Rama Prasad, at http://technoayurveda.wordpress.com/
  32. 32. Excellence of Rasaaushadhi In Ayurveda Practice – Part 2 technoayurveda@gmail.com THANK YOU Dr. K. Shiva Rama Prasad Of . . . technoayurveda.wordpress.com It’s on Technoayurveda International PresentationExcellence of Rasaaushadhi In Ayurveda Practice Dr. K. Shiva Rama Prasad, Professor & Head, Kayachikitsa, Amrita School of Ayurveda, Kerala 32

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