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Dhataki - Woodfordia Fruticosa, W. floribunda - Anti-leucorrhea activity - Anti-fertility activity - Immuno-active constituents

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  1. 1. Home http://www.technoayurveda.com/Dhataki.html Ayurveda Tradition to meet the Technology Home Ayurveda Service Research Women Download Jyotish About NEWS Contact-Us Division: Magnoliophyta Powered by Translate Dhataki - Woodfordia Fruticosa, W. floribunda Class:Magnoliopsida Order:Myrtales Dhataki [Woodfordia fruticosa] is common in Sri Lanka, South Konkan and on the Family:Lythraceae Ghats and ascends the Himalayas to 1500 m, but is rarer in South India. Dhataki Genus:Woodfordia (Fire Flame Bush) is a spreading, leafy shrub, small in size but very conspicuous on Species: Woodfordia Fruticosa, W. dry, rocky hillsides from December to May, when the masses of little fiery bells give floribunda a bright touch of color to the drab terrain. It is a deciduous shrub, usually with a Sanskrit: Dhataki, Parvati, Bahupuspika, much-fluted stem. The grey bark is exceedingly thin and peels off in flakes. When in Tamrapushpi flower the bush appears twiggy and formless but entirely swathed in red. This is English: Fire Flame Bush, Red Bell Bush because the small flowers grow singly or in groups all the way along the branches Hindi: Dhawai, Dhai phul and side twigs, and it is at this time that the leaves fall. Marathi: Dowari oTamil: Velakkai Malayalam: Tatiripuspi Constituents: Telugu: Jargi seringi, Godari The extracts of Woodfordia fruticosa flowers showed the presence of Kannada: Tamrapuspi carbohydrates, gums, flavonoids, sterols and phenolic compounds/tannins. HPTLC Oriya: Dhobo studies of extract 1 at 254 nm showed the presence of four spots (with Rf of 0.04, Konkani: Dhauri 0.19, 0.32, 0.40), extract 2 showed the presence five spots (with Rf of 0.06, 0.20, Urdu: Jetiko 0.32, 0.40, 0.56), extract 3 showed the presence six spots (with Rf of 0.06, 0.19, Gujarati: Dhawani 0.32, 0.40, 0.57, 0.67). The plates were sprayed with 5% alcoholic FeCl 3 reagent Part used - Flower, Bark, Leaves to check the presence of tannins. Extract 1 showed three blue-black spots at Rf of 0.05, 0.19, 0.34; extract 2 and extract 3 each showed two blue-black spots at Rf of 0.21, 0.34, indicating the presence of tannins. Medicinal Uses: The flowers are acrid, astringent, styptic, depurative, utreine sadative, constipating, antibacterial, corrective of urinary pigments, febrifuge and alexeteric. They are useful in the conditions of kapha and pitta, leprosy, burning sensation, skindiseases, diarrhoea, dysentery, fever, headache, hemorrhoids, herpes, internal hemorrhage, leukorrhea, liver disorders, menorrhagia, ulcers, wounds. Juice of leaves are used in bilious sickness. They are also valued as a stimulant in pregnancy. Studies on Woodfordia fruticosa : 1) Anti-fertility activity: Anti-fertility activity of dried flowers of Woodfordia fruticosa Kurz is studied with various solvents and individually with water and aqueous alcohol (50:50). Antifertility activity of successive alcoholic, individual aqueous and individual hydroalcoholic extracts was studied in female albino rats. Ayurveda Actions Proven fertile male and female Wistar rats (150-200 g) were used for the study. - Dashaprasamana - The protocol was approved by the IAEC (No. CUSCP/IAEC/02/2002-2003). The decreasing burning sensation. Pharmacological data rats were maintained at room temperature with natural daylight and given a - Jwaraghna - anti pyretic Rasa (taste): Kashaya (astringent), Katu standard pellet diet with water ad libitum. Female rats were divided into the - Krumighna - destroys (pungent) Parasites following four groups: Group I - control group - received distilled water orally. Guna (quality): Laghu (light), Ruksha (dry) - Kushthaghna - skin conditions Group II - received successive alcoholic extract (100 mg/kg body weight). Group III Virya (energy): Shita (cooling) - Mutravirajaniya - normalises - received 50% hydroalcoholic extract (100 mg/kg body weight). Group IV - Vipaka (post digestive effect): Katu (pungent) colour of urine received water extract (100 mg/kg body weight). Prabhava (Special quality): none - Rakta Pitta Shamaka - pacify Dosha Effect: KP- rakta pitta disorders The average number of implantation sites for all the treatment groups was lower as Dhatus (tissues): Rakta, Majja - Rakta sstambhana - stops compared to the control. This is an indication of antifertility activity. There was no Srotas (channels): Raktavaha, Annavaha bleeding significant difference in the average size of implantation sites for control and all the Principal Constituents: - Sandhaniya - bone fractures treatment group animals. For extract 1, which was successive alcoholic extract, the Woodfordins A, B, C, D, E, F, G, H, I and - Stambhana - prevents average number of implantation sites was 7.0, but the average number of litters were identified from the flowers. expulsion of fluids delivered was 4.0. This decrease in number of implantation sites may be due to - Swedajanana - promotes resorption of foetus. This is a strong indication of abortifacient activity. For individual References sweating hydroalcoholic extract (extract 2) and individual aqueous extract (extract 3), the [1] Khushalani H, Tatke P, Singh KK. Antifertility - Vranaropana - wound healing average number of implantation sites was 6.2 and 7.0 respectively, but the average activity of dried flowers of Woodfordia fruticosa properties number of litters delivered was 5.0 and 6.2 respectively. Among all the three kurz. Indian J Pharm Sci [serial online] 2006 [cited 2012 Mar 16];68:528-9. Available from: extracts tested, successive alcoholic extract showed maximum abortifacient activity Important Combinations http://www.ijpsonline.com/text.asp?2006/68/4/528 of 43%, which was found to be statistically significant ( P < 0.05) [Table - 1] . - Dhatakyadi churna (skin /27838 Individual aqueous and individual hydroalcoholic extract, though, showed moderate diseases, menorrhagia, [2] N. P. Patil, A comparative study Majuphala & activity of 12 and 20%; however, it was not statistically significant [1]. diarrhea, UTI, fever); Dhataki puspha in the management of sweta pradara, RGUHS, 2007 Dhatakyadi taila (Skin1 of 2 5/14/2012 8:21 AM
  2. 2. Home http://www.technoayurveda.com/Dhataki.html [3] Kroes BH, Vanden Berg AJJ, Abeysekera AM, 2) Anti-leucorrhea activity: diseases), De Silva KTD & Labadie RP, Fermentation in A clinical study of Majuphala powder & Dhataki pushpa powder to assess the effect - Laghu gangadhara churna traditional medicine: the impact of Woodfordia in leucorrhea is undertaken on 30 patients, were divided in three groups Group A of (gastric ulcers, diarrhea fruticosa flowers on the immunomodulatory activity 10 patients were received Majuphala Churna for 21 days & internally Yonidhavan and the alcohol and sugar contents of Nimba arishta, J Ethnopharmacol, 40 (1993) 117-125. done with Majuphala Decoction for 10 days. Group B 0f 10 patients received [http://www.sciencedirect.com/science/article internally Dhataki pushpa powder externally yonidhavana with Dhataki pushpa /pii/037887419390056B] powder for 10 days. Group C of 10 patients (Control group) were received wheat flour in above said same manner. Resources: - http://www.ayurwiki.info/wiki/dhataki The research work was concluded as follows- - http://www.oshims.com/herb-directory/d/dhataki - http://www.flowersofindia.in/catalog/slides - Group A (Majuphala) & B (Dhataki) had shown highly significant results in both /Fire%20Flame%20Bush.html cordial & associated symptoms of leucorrhea as compared to control group. - http://www.ecoplanet.in/Herbsandplants/WoodfordiaFruticosa.htm -http://en.wikipedia.org/wiki/Woodfordia_fruticosa - In local pathology group A (Majuphala) & Group B (Dhataki) showed significant http://www.sciencedirect.com/science/article results in group A (Majuphala) in cervisitis the results were significant. /pii/S0378874106006726 - Group B (Dhataki) showed significant results in Hb% [2]. 3) Immuno-active constituents in W. fruticosa Fermentation of both preparations (Asava & Arista) is brought about by the addition of a source of sugar with dhataki (Woodfordia fruticosa Kurz) flowers. Dhataki is fermentation initiator and jaggery as a source of sugar in Asava & Arista manufacturing. The use of Woodfordia flowers in model preparations resulted in a substantial increase of the inhibition of both human complement activity and chemiluminescence generated by zymosan-stimulated human polymorphonuclear leukocytes. It was established that the increased biological activity was not due to microbial interference, but to immuno-active constituents released from the Woodfordia flowers. Experiments performed with yeasts isolated from commercial Nimba arishtas showed, in agreement with empirical findings, significantly raised alcohol content upon addition of Woodfordia. [3].2 of 2 5/14/2012 8:21 AM