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Cellular panchakarma 2018 03-14


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This explains the molecular level of Ayurveda presented on 14-03-2018 at MHACGHRC, Wardha by DR KSR Prasad

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Cellular panchakarma 2018 03-14

  1. 1. Cellular Panchakarma (M l l P h k )(Molecular Panchakarma)  KSR Prasad P f P h kProfessor, Panchakarma @MGAC, Wardha on 14‐03‐2018 Dr. K. Shiva Rama Prasad, at
  2. 2. Introd ction Cellular / Molecular Panchakarma Introduction  • Ayurveda Panchakarma is a needAyurveda Panchakarma is a need  based, body end product toxic  deposition elimination methoddeposition elimination method  adopted physiology and natural  available resources to removeavailable resources to remove  depositions of unwanted toxins  naturally under controllednaturally under controlled   therapeutic  procedures.  Dr. K. Shiva Rama Prasad, at 1/16
  3. 3. Gross & Molec lar Panchakarma Cellular / Molecular Panchakarma Gross & Molecular Panchakarma • The Dosha explanation in presentThe Dosha explanation in present  scenario is easy when we  understand physiology of  contemporary using the applied  aspects of Ayurveda • If only looking at the literary  translations of Sanskrit verses of  A d i i dlAyurveda, its output is endless   debatable Dr. K. Shiva Rama Prasad, at 2/16
  4. 4. Macro Panchakarma Cellular / Molecular Panchakarma Macro Panchakarma • It is well known fact that the bodyIt is well known fact that the body  is divided in to 3 segments – – Thorax – Kapha ‐ Vamana– Thorax – Kapha ‐ Vamana – Upper abdomen – Pitta ‐ Virechana Lower abdomen Vata Vasti– Lower abdomen – Vata – Vasti  – And the upper part body i.e. Head ‐ NasyaNasya Dr. K. Shiva Rama Prasad, at 3/16
  5. 5. Micro or Cell lar Panchakarma Cellular / Molecular Panchakarma Micro or Cellular Panchakarma • In the body, cell is a unit structure y, • The evaluation of multi cellular  organisms  is a boon and has many  systems involved in itsystems involved  in it • The cell is independently active and  performs all activities of livingperforms  all activities of living  organism  • Cell has Respiratory, Digestive  (i ) C di l ( b li )(input), Cardiovascular (metabolic),  Urinary (output), Reproductive, etc.  systems  as in ‐ Amoebay Dr. K. Shiva Rama Prasad, at 4/16
  6. 6. Principles of Cell f nctions Cellular / Molecular Panchakarma Principles of Cell functions  1. Fluid (Ap dhatu) and it is distribution in ( p ) side cell (ICF) out side cell (ECF) and also  in between (IF) 2 H d H i t i t t f t2. Hydrogen ‐ pH is most important factor  to decide the diffusion and  permeability (Pitta)p y ( ) 3. Electrolytes – Na, K, and Cl creates and  maintains membrane potential (Vata) 4. Apart from mitochondria, lysosomes,   ribosomes, genetic material and many  more are involved (Kapha)more are involved (Kapha) Dr. K. Shiva Rama Prasad, at 5/16
  8. 8. Tridosha in Cell Cellular / Molecular Panchakarma Tridosha in Cell • Body is with Four basic elements y • Hydrogen [9.5] • Oxygen  [65.0] – H and O together becomes water and  the source of Transportation = Vata • Carbon [18 5]• Carbon [18.5] – CHO is the source of carbohydrates and  Lipids that are energy sources = Pitta • Nitrogen [3.2] – CHON is the source of proteins and  builds the protoplasm = Kaphabuilds the protoplasm   Kapha Dr. K. Shiva Rama Prasad, at 7/16
  9. 9. Elemental Dhat components Cellular / Molecular Panchakarma Elemental Dhatu components  • CHO is the nutrient and Rasa – do give only Under or Over nutritional effects  • Chlorine (Cl) [0.2] • Sodium (Na) [0.2] • Potassium (K) [0.4] Important constituents of body fluids to make transportation (Rasa– Important constituents of  body fluids to make transportation (Rasa  gati under khalekapota nyaya) • Calcium  [1.5] • Phosphorous [1.0]  • Iron [0.1]  – Components of Blood (Rakta) • Mamsa – Ca, K, Na,  Magnesium,  Iodine and Sulphur M d CHO f R• Meda – CHO of Rasa  • Asthi – Ca, P, S • Majja ‐ Mg, I  • Sukra Zn• Sukra – Zn,  Dr. K. Shiva Rama Prasad, at 8/16
  10. 10. Components infl ence Dosha Cellular / Molecular Panchakarma Components influence Dosha • Apart from all – – Electrical potentials  – Messengers  – Secretary enzymes – Signaling mechanisms g g – and many more …..  Dr. K. Shiva Rama Prasad, at 9/16
  11. 11. Cell Cellular / Molecular Panchakarma Cell Dr. K. Shiva Rama Prasad, at 10/16
  12. 12. Waste b prod cts of Cell Cellular / Molecular Panchakarma Waste byproducts of Cell • Energy = • Lactic acid fermentation – • CO2 is excreted from the cell – Up to 7% in blood plasma– Up to 7% in blood plasma. – About 70‐80% is hydrocarbonate ions, – The remainder in RBC carried to lungs • Nitrogenous Wastes • ammonia, which raises the pH of body  fluids – Converts in to Urea (BUN) ( ) b– uric acid (antioxidant) but cause  inflammation  Dr. K. Shiva Rama Prasad, at 11/16
  13. 13. Hea Metals Cellular / Molecular Panchakarma Heavy Metals • Arsenic, cadmium, copper, lead, mercury, zinc  and Aluminum (not a heavy) Dr. K. Shiva Rama Prasad, at 12/16
  14. 14. Cell To icit Cellular / Molecular Panchakarma Cell Toxicity  Category System affected Common symptoms respiratory nose, trachea,  lungs irritation, coughing, choking, tight chest shwasa gastrointestinal stomach, intestines nausea, vomiting, diarrheag g renal kidney back pain, urinating more or less than  usual headache dizziness behavior confusion neurological brain, spinal cord headache, dizziness, behavior confusion,  depression, coma, convulsions hematological blood anemia (tiredness, weakness) dermatological skin, eyes rashes, itching, redness, swelling reproductive ovaries, testes,  fetus infertility, miscarriage Dr. K. Shiva Rama Prasad, at 13/16
  15. 15. Nitro en astes Cellular / Molecular Panchakarma Nitrogen wastes 1. Ammonia (NH3)  ‐ Most ammonia in the  b d f h i i b k d bbody forms when protein is broken down by  bacteria in the intestines . The liver normally  converts ammonia into urea 2. Urea ‐ It requires 0.05 L of water to excrete  1 g of nitrogen,  3 Uric acid – it is the least soluble in water3. Uric acid  it is the least soluble in water  and can be stored in cells and body tissues  without toxic effects 4 C ti i it i b d t f l4. Creatinine ‐ it is byproduct of muscle  metabolism signifies impaired kidney  function,  effective at killing bacteria Dr. K. Shiva Rama Prasad, at 14/16
  16. 16. Other astes Cellular / Molecular Panchakarma Other wastes 1. CO2 is a waste product of Respiration  2 Nitrates and nitrites are wastes produced by2. Nitrates and nitrites are wastes produced by  nitrifying bacteria, just as sulfur and sulfates are  produced by sulfur‐reducing bacteria and sulfate‐ reducing bacteria.  3. Insoluble iron waste can be made by iron bacteria  by using soluble forms.y g 4. Solid waste products may be manufactured as  organic pigments derived from breakdown of  pigments like hemoglobin and inorganic salts likepigments like hemoglobin, and inorganic salts like  carbonates, bicarbonates, and phosphate,  whether in ionic or molecular form, are excreted  Dr. K. Shiva Rama Prasad, at as solids.[3] 15/16
  17. 17. Sta es of Elimination Cellular / Molecular Panchakarma Stages of Elimination 1. The stage of accumulation g (Sanchaya)   2. Stage of augmentation (prakopa) Disease 3. Stage of adherence (snehana) 4. Stage of migration (Anupravana)  f ICF t IF (Bl d) Shakha Prasarana from ICF to IF (Blood) 5. Stage of transportation to  Koshta (Swedana) Koshta Gata Dosha Koshta (Swedana) 6. Stage of elimination (shodhana)  ‐ Vamana, Virechana, Niruha Vasti Shodhana , , Dr. K. Shiva Rama Prasad, at 16/16
  18. 18. Thank o Cellular / Molecular Panchakarma Thank you Dr. K. Shiva Rama Prasad, at