TcSNP – A map of Trypanosoma cruzi genetic variation
Laboratorio de Genómica y Bioinformática
Instituto de Investigaciones Biotecnológicas
Universidad de San Martín
What is TcSNP?
TcSNP is an online resource with information on
genetic variation (polymorphisms, mutations) for
different stocks, strains and isolates of Trypanosoma
cruzi, the causative agent of Chagas Disease
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What can you do in TcSNP?
●Access a sequence alignment containing your gene of interest, see
polymorphic sites, type of mutation, dN/dS ratio, etc.
●Find aligned genes/sequences that satisfy specific rules: participate in a given
metabolic pathway, has more/less than a given number of SNPs, has a
particular dN/dS ratio, etc.
●Find SNPs based on diferent criteria: detected between specific strains, that
cause synonymous/nonsynonymous/nonsense mutations,etc.
●Combine single queries making complex queries (doing unions, intersetions,
and substractions of queries)
●Explore multiple sequence alignments
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Search by queries
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