Plegable

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Plegable

  1. 1. TATIANA ZAPATA CORREA STUDENT MEDICINE
  2. 4. There are a new way for measure the telomeres with small amounts of DNA by PCR method and it allows direct comparison of results within and between laboratories   Cygnus pharmaceutical company creates a test called Host cell proteins in CHO and E. coli, it speed up laboratory testing and provide analytical measures in samples of small volume
  3. 5. A quantitative PCR method for measuring absolute telomere length Source Bioscience, life science (Jan. 2, 2011)  
  4. 6. <ul><li>Describe a simple method to measure absolute telomere length (aTL) using qualitative real-time polymerase chain reaction (qPCR). </li></ul><ul><li>This method is based on the Cawton method for relative measurement of telomere length (TL) but modified by introducing an oligomer standard to measure aTL. </li></ul>A quantitative PCR method for measuring absolute telomere length Source Bioscience, life science (Jan. 2, 2011)
  5. 7. <ul><li>The method describes the oligomer standards, the generation of the standard curve and the calculations required to calculate aTL from the qPCR data. </li></ul>A quantitative PCR method for measuring absolute telomere length Source Bioscience, life science (Jan. 2, 2011)
  6. 8. <ul><li>This method allows high throughput measurement of aTL using small amounts of DNA making it amenable for molecular epidemiological studies. </li></ul>A quantitative PCR method for measuring absolute telomere length Source Bioscience, life science (Jan. 2, 2011)
  7. 9. <ul><li>Compared to the traditional relative TL qPCR assays, the aTL method described enables a more direct comparison of results between experiments within and between laboratories. </li></ul>A quantitative PCR method for measuring absolute telomere length Source Bioscience, life science (Jan. 2, 2011)
  8. 11. Immunoassay kits Drug Discovery & Development (Jan 7, 2011)
  9. 12. <ul><li>Cygnus Technologies Inc. and Radix Biosolutions have launched kits specifically designed for compatibility with the company’s immunoassay platform. </li></ul><ul><li>The kits are intended to save time and labor during biotherapeutic development and production. </li></ul>Immunoassay kits Drug Discovery & Development (Jan 7, 2011)
  10. 13. <ul><li>Scientists optimizing purification processes and working in process control, routine QC and product release testing will benefit from the convenience of ready to use kits while maximizing their efficiency by utilizing the automated immunoassay platform.  </li></ul>Immunoassay kits Drug Discovery & Development (Jan 7, 2011)
  11. 14. <ul><li>The goal of the new immunoassay kit is to provide analytical measurements for customers that need to evaluate the pharmacokinetics of their antibody-based biotherapeutics in low-volume samples. </li></ul>Immunoassay kits Drug Discovery & Development (Jan 7, 2011)
  12. 15. <ul><li>The kit has been developed under Fit-for-Purpose standards and the core principles of the 21st Century Bioanalytical Lab Initiative to ensure highest performance and facilitate lab to lab harmonization. </li></ul>Immunoassay kits Drug Discovery & Development (Jan 7, 2011)
  13. 18. <ul><li>These studies are important to medicine </li></ul><ul><li>Because: </li></ul><ul><li>They could be used in early cancer diagnoses </li></ul><ul><li>To know the cell age of a person </li></ul><ul><li>To measure levels of hormones, viruses, cancer and exposure to infectious agents </li></ul><ul><li>To measure the levels of a drug in blood </li></ul>
  14. 19. <ul><li>Source Bioscience, life science, United States.[Index]. </li></ul><ul><li>Drug discovery & Development, United States. [Index]. </li></ul><ul><li>MARTINEZ S, Lina María. Biología Molecular. 6 ed. Medellín .UPB. Facultad de Medicina, 2011. p 113-123 </li></ul>

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