Muscular Dystrophy Facts• Muscular Dystrophy (MD) is a genetic disorder that causes weakness in the muscles that allow your body to move.• MD can be diagnosed via muscular biopsy.• MD refers to a group of genetic or hereditary disorders that destroy the muscles• MD varies from the age of onset, the muscles that initially attack and the rate of progression.• Specific symptoms include: wasting of muscles, poor balance, pain in the calves, limited range of movement, joint contractures, and vision problems.
Dystrophin• Dystrophin deficiency has been definitively established as one of the root causes of the general class of myopathies collectively referred to as muscular dystrophy. The large cytosolic protein was first identified in 1987 by Louis M. Kunkel, after the 1986 discovery of the mutated gene that causes Duchenne muscular dystrophy (DMD).
There are several types of Muscular Dystrophy Duchenne muscular dystrophy Becker muscular dystrophy Emery-Dreifuss muscular dystrophy Limb-girdle muscular dystrophy Facioscapulohumeral muscular dystrophy Mytonic dystrophy Congenital muscular dystrophy
Duchenne’s Duchenne muscular dystrophy (DMD) is the most common type and is caused by a defect with the gene that makes a protein called dystrophin. Without the protein, the muscles break down and a person gradually becomes weaker.
DMDDMD affects boys and usually beginssomewhere between ages 2-6. By age 10-12,kids often need to use a wheelchair. The heartmay also be affected, so they need to bemonitored closely by a cardio-pulmonaryspecialist. They can also develop curvature of thespine and tightness in their joints.Unfortunately, over time, the muscles thatcontrol their breathing become weaker andthey may need a ventilator to breathe. Peoplewith this type of MD usually do not survivebeyond their late teens or early adulthood.
This graph shows the total number of publications written about “Mucsular Dystrophy, Duchenne” by year, and weather “Muscular Dystrophy, Duchenne” was a major or minor topic of these publications. Publications written by people in UCS Profiles.
Links to Muscular Dystrophy Resourceshttp://profiles.ucsf.edu/display/349973http;//mda.org/www.helpful-health.com/diseases/muscular-dystrophy
ReferencesMickey Lieberman uses his diverse medical backgroundand experience to research helpful health information onnumerous diseases and illnesses and provides useful resourcesfor over 100 different medical conditions.Citation: Disabled World News (2009-02-27) - MuscularDystrophy is not just one disease the term refers to a group ofgenetic or hereditary disorders that destroy the muscles: