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Hsv treatment by aseem

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Hsv treatment by aseem

  1. 1. MANAGEMENT REGIMES FOR HERPES SIMPLEX INF
  2. 2. SYMPTOMATIC MANAGEMENT • Maintain Hygeine, Keep area dry and clean • Treatment indicated in case of Persistence, Burning / Pain / Fever, Superadded infection, • TOPICALS DOCOSANOL 10% CREAM LA 5 TIMES DAILY X 07-10 DAYS PENCICLOVIR 1% CREAM LA q 2 hrs X 07-10 DAYS ACYCLOVIR 5% CREAM LA 5 TIMES DAILY X 07-10 DAYS (Muco-adhesive Buccal Tablet (Sitavig 50mg) Single dose to Canine Fossa)
  3. 3. SYSTEMIC ANTIVIRALS REDUCTION : Healing time of lesions 16  12 days 07  05 days Post-herpetic pain 07  05 days 04  02 days Constitutional symp 06  03 days 04  03 days No effect on Latency
  4. 4. ORO-FACIAL HERPES PRIMARY INFECTION T ACYCLOVIR 400 mg TDS X 07-10 days T VALACYCLOVIR 1 g BD X 07-10 days T FAMCICLOVIR 250 mg TDS X 07-10 days ACYCLOVIR 15 mg/kg/dose 5 times a day x 07-10 days (Pediatric) Also for Herpes Gladiatorum / Whitlow / Scrumpox
  5. 5. ORO-FACIAL HERPES • RECURRENT : EPISODIC T ACYCLOVIR 400 mg 5 times a day X 04-05 d T VALACYCLOVIR 2 g BD X 01 d T FAMCICLOVIR 500 mg TDS X 01 d
  6. 6. ORO-FACIAL HERPES • RECURRENT : SUPPRESSION T ACYCLOVIR 400 mg BD x 12 months
  7. 7. GENITAL HERPES (CDC-2010) • PRIMARY INFECTION T ACYCLOVIR 400 mg TDS X 07-10 days T VALACYCLOVIR 1 g BD X 07-10 days T FAMCICLOVIR 250 mg TDS X 07-10 days Extended > 10 days if inadequate healing ACYCLOVIR 15 mg/kg/dose 5 times a day x 07-10 days (Pediatric)
  8. 8. GENITAL HERPES • RECURRENT : EPISODIC T ACYCLOVIR 400 mg TDS X 05 d T VALACYCLOVIR 1g OD X 05 d T FAMCICLOVIR 125 mg BD X 05 d
  9. 9. GENITAL HERPES • RECURRENT : SUPPRESSION T ACYCLOVIR 400 mg BD X 12 months T VALACYCLOVIR 500 mg BD X 12 months T FAMCICLOVIR 250 mg TDS X 12 months
  10. 10. GENITAL HERPES • RECURRENT : SUPPRESSION in PREGNANCY T ACYCLOVIR 400 mg TDS 36th Week of Gestation till Delivery
  11. 11. OCULAR HERPES • PRIMARY INFECTION T ACYCLOVIR 400 mg 5 times a day T VALACYCLOVIR 1 gm BD Topical 1 % ED TRIFLURIDINE, 0.1 % ED IDOXURIDINE or 0.5 % Ointment, 3 % Ointment VIDARABINE q 2 hrs Day + q 4 hrs Night
  12. 12. OCULAR HERPES • RECURRENCE : SUPPRESSION T ACYCLOVIR 400 mg TDS X 12 months
  13. 13. NEONATAL HERPES • Inj ACYCLOVIR 20 mg/kg/dose TDS x 02 – 03 weeks (Max 80 mg/kg/day)
  14. 14. ECZEMA HERPETICUM T ACYCLOVIR 400 mg TDS X 14-21 days T VALACYCLOVIR 1 g BD X 14-21 days T FAMCICLOVIR 250 mg TDS X 14-21 days Inj ACYCLOVIR 10-15 mg/kg/dose TDS X 02 -03 weeks
  15. 15. HERPES SIMPLEX ENCEPHALITIS • Inj ACYCLOVIR IV 10-15 mg/kg/dose TDS X 14-21 days Also for Disseminated Herpes Simplex Inf
  16. 16. THANK YOU

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