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Blaschkoid dermatitis

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Blaschkoid dermatitis

  1. 1. BLASCHKOID DERMATITIS
  2. 2. Introduction • 1901: German dermatologist Alfred Blaschko (1858-1922) ; retrospective • No Nervous, Vascular or Lymphatic correspondence • developmental growth pattern of the skin; pattern of Ectodermal Migration and Proliferation from Neural Crest
  3. 3. • V-shape – Upper Back, Neck, Upper Trunk • S-shape – Lateral Trunk • Inverted U-shape - breast area / Upper Arms • Perpendicular - lower extremities, Forearms • ‘Respect the Midline’ • Koebner's phenomenon but the curvature of the lesions does not support this hypothesis • Less defined on the head and neck • Happle et al  posterior scalp whereas • Bolognia et al  lateral aspect face and neck • Equivalent over teeth and eyes
  4. 4. • aa
  5. 5. • aa
  6. 6. Embryological Etiological basis • No Vascular / Nervous / Lymphatic • Jackson – localization determined by the dermal tissues • ? Inborn error of morphogenesis due to a single mutant gene • ? stretching of the skin during embryogenesis • ? Mosaicism and Lyonization
  7. 7. • aa
  8. 8. Langer's lines / Cleavage lines, - correspond to the natural orientation of Collagen / Muscle fibres. Used in forensic science & surgical techniques.
  9. 9. • Kraissl's lines –anatomical Tension skin lines ; Cadavers • Cox – Tension Skin Lines • Borges – Relaxed TSL
  10. 10. • Voigt Lines – Pigmentary demarcatory lines over body ; the boundaries of the Areas of distribution of the cutaneous nerve stems ; attributed to hormones
  11. 11. • a
  12. 12. • aa
  13. 13. • aa
  14. 14. • aa
  15. 15. • aa
  16. 16. • h
  17. 17. THANK YOU

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