• Also known as i. Parkinsons, ii. Idiopathic parkinsonism, iii. Primary parkinsonism, iv. PD, v. Paralysis agitans• a group of conditions called motor system disorders, which results from the death of dopamine-containing cells in the substantia nigra, a region of the midbrain.• It can be passed down from generation to generation
• In today’s times, 1 out of 100 people that are over 60 years of age have Parkinson’s Disease.• Additionally, there are about 1.5 million people in the United States who currently have this life-controlling disease• Fifty eight percent of these 1.5 million people that have Parkinson’s Disease are men• In Malaysia, based on year 2009,statistic has shown that 26,786 people has been recorded to have Parkinson in interval of 5 years.
Medical scientists have been treating Parkinsons forthousands of years At the ancient time,Parkinsons disease are discussedin Ayurveda since as early as 5000 BC- Kampavata A condition like Parkinsons disease also wasmentioned in Nei ChingIn Western medical literature it was described byGalen as "shaking palsy“In modern times, Parkinsons disease was firstformally recognized by James Parkinsons -"An Essayon the Shaking Palsy"
TREMOR STIFF MUSCLESSLOW AND Weakness of face LIMITED and throat musclesMOVEMENT Difficulty with Speech becomes walking (gait softer and disturbance) and monotonous - balance (postural"Parkinsons mask“ instability)
Parkinsons disease is an ideophatic syndrome (having no known cause/factors) But the main causes is Parkinsonism can be caused by any damage that is done to the substantia nigra. Scientists have found that there is a gene called alpha synuclein -inherited It also can be caused by drugs or certain chemicals - Manganese, Carbon Monoxide, Cyanide and Carbon Disulfide Hypothyroidism
a person’s medical neurological history exams • blood tests -abnormal thyroid hormone levels or liver damag • CT scan or an MRI -check for signs of a stroke or brain tumor.
HOME TREATMENT:• modifying your activities and your home - simplifying your daily activities and changing the location of furniture• to take a healthy foods -fruits, vegetables, grains, cereals, legumes, poultry, fish, lean meats, and low-fat dairy products• Exercising and doing physical therapy – move the body part
• No cure for PD• Patients are given Levodopa combined with Carbidopa levodopa: to make dopamine and replenish thebrains dwindling supply carbidopa: delays the conversion of levodopa intodopamine until it reaches the brain• In some cases, a surgery may be appropriate –if it did not responds to the drug