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Insomnia
Sleep <ul><li>Sleep is a state of unconsciousness in which the brain is relatively more responsive to internal than to ext...
Sleep  through out life
Why do we sleep? <ul><li>To support normal levels of cognitive skills such as  </li></ul><ul><li>Speech </li></ul><ul><li>...
Average Sleep Needs   7.5 - 9 Adults (18+) 8.5 - 10 Teens and preteens (12 to 18 years) 10-11  School-aged children (5 to ...
Sleep Cycle <ul><li>Sleep is divided into two broad types: rapid eye movement (REM) and non-rapid eye movement (NREM or no...
Sleep pattern in children <ul><li>Baby sleep cycles are far shorter than those of adults </li></ul><ul><li>Babies spend mo...
<ul><li>Insomnia is defined as difficulty with the initiation, maintenance, duration, or quality of sleep that results in ...
Causes of Insomnia in Children  <ul><li>Teething  </li></ul><ul><li>fretfulness </li></ul><ul><li>repeated indigestion wit...
Treatment of Insomnia <ul><li>Commonly prescribed off-label to treat pediatric patients with insomnia including alpha agon...
Side Effects with Other Drugs <ul><li>Narrow therapeutic window  </li></ul><ul><li>A high risk for cardiovascular toxicity...
<ul><li>Triclofos sodium </li></ul>Introducing
Triclofos <ul><li>A sedative drug used  for treating insomnia, usually as a second-line treatment after other drugs have f...
Triclofos <ul><li>Triclofos is a prodrug which is metabolized in the liver into the active drug trichloroethanol which act...
Why Pednap <ul><li>Drug of Natural origin </li></ul><ul><li>Very safe for children below 5 yrs </li></ul><ul><li>It is a w...
<ul><li>More palatable. </li></ul><ul><li>Causes less gastric irritation. </li></ul><ul><li>Less Respiratory rate Fluctuat...
Target Customers <ul><li>Pediatricians </li></ul><ul><li>Physicians </li></ul>
Competition – Pednap 28 30ML TRICLOFOS SODIUM EAST AFRICAN FOSKID 55 30ML TRICLOFOS MAXX INDIA SNOOZ 38.00 60ML TRICLOFOS ...
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Pednap

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Presentation by shalini kumari,product manager,Hyderabad on Triclofos

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Pednap

  1. 1. Insomnia
  2. 2. Sleep <ul><li>Sleep is a state of unconsciousness in which the brain is relatively more responsive to internal than to external stimuli. </li></ul>
  3. 3. Sleep through out life
  4. 4. Why do we sleep? <ul><li>To support normal levels of cognitive skills such as </li></ul><ul><li>Speech </li></ul><ul><li>memory </li></ul><ul><li>innovative and flexible thinking. </li></ul><ul><li>Very Important for brain development. </li></ul><ul><li>For Concentration </li></ul><ul><li>For Physical and Emotional fitness </li></ul>
  5. 5. Average Sleep Needs 7.5 - 9 Adults (18+) 8.5 - 10 Teens and preteens (12 to 18 years) 10-11 School-aged children (5 to 12 years) 11-13 Preschoolers (3 to 5 years) 12-14 Toddlers (1 to 3 years) 14 - 15 Infants (3 months to 1 year) 12-18 Newborns (0-2 months) Hours Age Average Sleep Needs
  6. 6. Sleep Cycle <ul><li>Sleep is divided into two broad types: rapid eye movement (REM) and non-rapid eye movement (NREM or non-REM) sleep. </li></ul><ul><li>Each type has a distinct set of associated physiological, neurological, and psychological features. </li></ul>
  7. 7. Sleep pattern in children <ul><li>Baby sleep cycles are far shorter than those of adults </li></ul><ul><li>Babies spend more time in rapid eye movement (REM) sleep, which is thought to be necessary for the extraordinary development happening in their brain. </li></ul><ul><li>REM sleep is lighter than non-REM sleep, and more easily disrupted. </li></ul>
  8. 8. <ul><li>Insomnia is defined as difficulty with the initiation, maintenance, duration, or quality of sleep that results in the impairment of daytime functioning, despite adequate opportunity and circumstances for sleep. </li></ul><ul><li>Patient’s subjective dissatisfaction with the sleep quality and quantity </li></ul>Insomnia
  9. 9. Causes of Insomnia in Children <ul><li>Teething </li></ul><ul><li>fretfulness </li></ul><ul><li>repeated indigestion with persistent crying </li></ul><ul><li>Excitability and restlessness </li></ul><ul><li>Difficult feeding </li></ul><ul><li>Disruption of sleep patterns </li></ul>
  10. 10. Treatment of Insomnia <ul><li>Commonly prescribed off-label to treat pediatric patients with insomnia including alpha agonists e.g. Clonidine, Guanfacine </li></ul><ul><li>Trazodone </li></ul><ul><li>Benzodiazepines and </li></ul><ul><li>Newer sedatives/hypnotics such as Non benzodiazepines as Zolpidem, Eszopiclone and Triclofos etc. . </li></ul>
  11. 11. Side Effects with Other Drugs <ul><li>Narrow therapeutic window </li></ul><ul><li>A high risk for cardiovascular toxicity </li></ul><ul><li>Risks of physical dependence </li></ul><ul><li>Rebound insomnia </li></ul><ul><li>Cause unpredictable excitation in younger children. </li></ul>
  12. 12. <ul><li>Triclofos sodium </li></ul>Introducing
  13. 13. Triclofos <ul><li>A sedative drug used for treating insomnia, usually as a second-line treatment after other drugs have failed. </li></ul><ul><li>Belongs to category of potentiates the cns depressants like sedative, barbiturates drugs. </li></ul><ul><li>Well tolerated & effective non barbiturate sleep promoting agent conspicuously free from tendency to cause ‘hang over’ & other side effects. </li></ul>
  14. 14. Triclofos <ul><li>Triclofos is a prodrug which is metabolized in the liver into the active drug trichloroethanol which acts as a sedative. </li></ul>
  15. 15. Why Pednap <ul><li>Drug of Natural origin </li></ul><ul><li>Very safe for children below 5 yrs </li></ul><ul><li>It is a well tolerated & effective non barbiturate sleep promoting agent conspicuously free from tendency to cause 'hang over' and other side effects. </li></ul><ul><li>Triclofos decreases the time taken to fall asleep and increases the length of time spent sleeping. </li></ul>
  16. 16. <ul><li>More palatable. </li></ul><ul><li>Causes less gastric irritation. </li></ul><ul><li>Less Respiratory rate Fluctuations. </li></ul><ul><li>Fewer G.I side effects. </li></ul>
  17. 17. Target Customers <ul><li>Pediatricians </li></ul><ul><li>Physicians </li></ul>
  18. 18. Competition – Pednap 28 30ML TRICLOFOS SODIUM EAST AFRICAN FOSKID 55 30ML TRICLOFOS MAXX INDIA SNOOZ 38.00 60ML TRICLOFOS SODIUM GLAXO TRYCLORYL 44.50 30ML TRICLOFOS SODIUM DR REDDY PEDICRORYL 38 30ML TRICLOFOS SODIUM SALUD SLEP Price per Strip Packaging (BOTTLE) Composition Company Brand Name
  19. 19. The End

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