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High quality information has a significant impact on improving hospital efficiency and patient satisfaction, as well as resolving patient disputes. In this paper, on the basis of the analysis of the research status of information quality and process performance, information quality is considered as an important contributory factor in improving patient throughput. A theoretical framework and main content are presented. Through the establishment of quantitative information, quality indicators such as correctness, timeliness and completeness, and the impact on process performance (registered queue length, waiting time, utilization of hospital facilities), together with the cost of the operating process, is analyzed from the theoretical aspect and then verified by simulation technology. Finally, the significance and feasibility of this study are clarified.