Gene Structure: Polycistronic vs monocistronic <ul><li>Cistron :  an old name for a gene </li></ul><ul><li>Polycistronic :...
Monocistronic vs Polycistronic Transcription <ul><li>Prokaryotes – Both  </li></ul><ul><li>Eukaryotes </li></ul><ul><ul><l...
Why does prokaryotes have polycistronic while eukaryotes have monocistronic? <ul><li>Eukaryotes don’t need everything so b...
The  lac  Operon P O lacZ lacY lacA P O lacZ lacY lacA mRNA 5’ 3’ RIBSOSOME BINDING SITE Q:  How many proteins are made?
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Polycistronic gene

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Ncert plus two biology surendran aduthila

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  • -Why does prokaryotes have polycistronic while eukaryotes have monocistronic? -Eukaryotes don’t need everything so by using monocistronic, they can regulate what is being created without creating too much of unnecessary resources. Prokaryote uses polycistronic because they genome is small and want to make everything in one pathway together.
  • Polycistronic gene

    1. 1. Gene Structure: Polycistronic vs monocistronic <ul><li>Cistron : an old name for a gene </li></ul><ul><li>Polycistronic : 1 promoter directs synthesis of 1 mRNA that can be translated to more than one polypeptide </li></ul><ul><ul><li>Prokaryotic genes </li></ul></ul><ul><li>Monocistronic : 1 promoter directs synthesis of 1 mRNA that usually translates to only 1 protein </li></ul><ul><ul><li>Eukaryotic genes </li></ul></ul>
    2. 2. Monocistronic vs Polycistronic Transcription <ul><li>Prokaryotes – Both </li></ul><ul><li>Eukaryotes </li></ul><ul><ul><li>Nucleus – Monocistronic (polycistronic rare) </li></ul></ul><ul><ul><li>Mitochondria </li></ul></ul><ul><ul><ul><li>Mammals – polycistronic (2 promoters); pre-RNAs processed into smaller species </li></ul></ul></ul><ul><ul><ul><li>Other – Both </li></ul></ul></ul><ul><ul><li>Chloroplast - Both </li></ul></ul>
    3. 3. Why does prokaryotes have polycistronic while eukaryotes have monocistronic? <ul><li>Eukaryotes don’t need everything so by using monocistronic, they can regulate what is being created without creating too much of unnecessary resources. </li></ul><ul><li>Prokaryote uses polycistronic because they genome is small and want to make everything in one pathway together. </li></ul>
    4. 4. The lac Operon P O lacZ lacY lacA P O lacZ lacY lacA mRNA 5’ 3’ RIBSOSOME BINDING SITE Q: How many proteins are made?

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