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Cancer
Pancreas
Prepared By
SwatilekhaDas
RN, BSN, MSN
2
SWATILEKHA DAS
Cancer
Pancreas
Risk factors
Risk factorsinclude
• cigarettesmoking
• exposure to industrial
chemicals or toxinsin
the environment
• a diet high in fat, meat,
or both
• Pancreaticcancer is
also associated with
diabetes mellitus,
chronic pancreatitis,
and hereditary
pancreatitis.
4
SWATILEKHA DAS
Clinical
Manifestations
• Pain, jaundice, or both are present
in more than 80% of patients and,
along with weight loss
• Rapid, profound,and progressive
weight loss.
• Vague upper- or midabdominal pain
or discomfort unrelated to any GI
function; radiates as a boring pain in
the mid back Symptoms of insulin
deficiency (diabetes: glucosuria,
hyper-glycemia, and abnormal
glucose tolerance) may be an early
sign of carcinoma.
5
SWATILEKHA DAS
CLINICAL
MANIFESTATIONS
• Meals often aggravateepigastric pain.
• Malabsorption of nutrients and fat-soluble
vitamins, anorexia and malaise, and clay-colored
stools and dark urine are common
SWATILEKHA DAS 6
Assessment
and
Diagnostic
Methods
• Spiral (helical) CT
• MRI scan
• endoscopic retrograde
cholangiopancreatography
(ERCP)
• GI x-rays, percutaneous fine-
needle biopsy,
• percutaneous transhepatic
cholangiography (PTC), angiog-
raphy, laparoscopy, or
intraoperative ultrasonography
• Glucose tolerance test
7
SWATILEKHA DAS
Surgical
treatment
SWATILEKHA
DAS
• Surgical procedure is
extensive to remove
resectable localized tumors
(eg, pancreatectomy, Whipple
resection).
8
SWATILEKHA DAS 9
10
SWATILEKHA DAS
SWATILEKHA DAS 11
SWATILEKHA DAS 12
Medical
Management
• Radiation and chemotherapy may
be used; intraoperative radiation
therapy (IORT) or interstitial
implantation of radioactive
sources may be used for pain
relief.
13
SWATILEKHA DAS
Medical Management
SWATILEKHA
DAS
• Diet high in protein with pancreatic enzymes, adequate
hydration, vitamin K, and treatment of anemia with blood
components and total Parenteral Nutrition may be instituted
before surgery when indicated.
14
A biliary stent may
be used
to relieve jaundice
15
Thank You
16
SWATILEKHA DAS

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