In Vitro Fertilization
What is In Vitro Fertilization (IVF)? <ul><li>Process by which egg cells are fertilized by sperm outside of the womb </li>...
Method <ul><li>Ovarian Stimulation </li></ul><ul><li>Treatment starts on the third day of menstruation </li></ul><ul><li>F...
Method <ul><li>2. Egg Retrieval </li></ul><ul><li>Eggs are retrieved using a transvaginal technique using a needle to pier...
Method <ul><li>3. Fertilization </li></ul><ul><li>Sperm and egg are incubated together (at a ratio of 75 000:1) for about ...
Method  <ul><li>4. Embryo Transfer </li></ul><ul><li>The “best” embryos are transferred to the uterus using a thin, plasti...
For IVF to be Successful … <ul><li>Need healthy ova (egg) </li></ul><ul><li>Healthy sperm – that can fertilize  </li></ul>...
Success Rate <ul><li>Pregnancy rate = success rate for pregnancy  </li></ul><ul><li>For IVF, success rate is the percentag...
Complications <ul><li>Major complication is risk of multiple births – related to the practice of transferring multiple emb...
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In Vitro Fertilization

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In Vitro Fertilization

  1. 1. In Vitro Fertilization
  2. 2. What is In Vitro Fertilization (IVF)? <ul><li>Process by which egg cells are fertilized by sperm outside of the womb </li></ul><ul><li>Major treatment for infertility </li></ul><ul><li>Process involves hormonally controlling ovulation, removing eggs from the ovaries and letting sperm fertilize the eggs in a fluid medium  fertilized egg (zygote) is transferred to woman’s uterus </li></ul>
  3. 3. Method <ul><li>Ovarian Stimulation </li></ul><ul><li>Treatment starts on the third day of menstruation </li></ul><ul><li>Fertility medications are administered – 10 days of injections are necessary </li></ul>
  4. 4. Method <ul><li>2. Egg Retrieval </li></ul><ul><li>Eggs are retrieved using a transvaginal technique using a needle to pierce the vaginal walls (to reach the ovaries) </li></ul><ul><li>10 to 30 eggs are removed </li></ul>
  5. 5. Method <ul><li>3. Fertilization </li></ul><ul><li>Sperm and egg are incubated together (at a ratio of 75 000:1) for about 18 hours </li></ul><ul><li>The fertilized egg is put in a special growth medium and left for about 48 hours until it has reached the 6-8 cell stage </li></ul>
  6. 6. Method <ul><li>4. Embryo Transfer </li></ul><ul><li>The “best” embryos are transferred to the uterus using a thin, plastic catheter – which goes through the vagina and cervix </li></ul><ul><li>Some embryos may be passed into the uterus to improve changes of pregnancy </li></ul>
  7. 7. For IVF to be Successful … <ul><li>Need healthy ova (egg) </li></ul><ul><li>Healthy sperm – that can fertilize </li></ul><ul><li>Uterus – that can maintain a pregnancy </li></ul><ul><li>IVF can be used for females who have already gone through menopause </li></ul>
  8. 8. Success Rate <ul><li>Pregnancy rate = success rate for pregnancy </li></ul><ul><li>For IVF, success rate is the percentage of all attempts that lead to pregnancy </li></ul><ul><li>In 2006, Canadian clinics reported an average pregnancy rate of 35% and a live birth rate of 27% </li></ul>
  9. 9. Complications <ul><li>Major complication is risk of multiple births – related to the practice of transferring multiple embryos at embryo transfer </li></ul><ul><li>Multiple births – related to increased risk of pregnancy loss, obstetrical complications, prematurity, and death </li></ul>

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