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Case 1

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Case 1

  1. 1. + Case 1 Suma, Kathryn, Patrick, Sid
  2. 2. + Patient History  Seven year-old male  Fatigue  Muscle weakness  Low endurance  Loss of coordination  Progressive difficulty walking
  3. 3. + Physical Examination  Muscle loss & deformity  Awkward gait  Difficulty breathing
  4. 4. + Laboratory Results  Cells have abnormal shape  Cell division is abnormal  Impaired intracellular movement of materials
  5. 5. + Diagnosis  Malfunctioning organelle- the microfilaments
  6. 6. + Rationale  Supports the cell  Pulls apart chromosomes in mitosis  Moves materials inside the cell  Actin and myosin, two microfilaments, cause muscle contractions  Causes abnormal cell shape  Causes abnormal cell division  Faulty movement of cellular materials  Muscle loss and deformity Cytoskeleton roles: Malfunctions cause:

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