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Breakthrough In HIV/Cancer <ul><li>Graham and Hayes Blog Assignment #2 </li></ul>
What’s the breakthrough? <ul><li>Molecules called &quot; a ntibody- r ecruiting  m olecule targeting  H IV&quot; (ARM-H)  ...
How does it work? <ul><li>The ARMs coat these antibodies  </li></ul><ul><li>The cells are flagged as threat to body </li><...
Why is this a breakthrough?  <ul><li>&quot;Instead of trying to kill the pathogens directly, these molecules manipulate ou...
Significance <ul><li>These new antibody triggers are just now only being tested on mice.  </li></ul><ul><li>If proven to b...
Sources Cited <ul><li>Yale University. &quot;New Synthetic Molecules Trigger Immune Response To HIV And Prostate Cancer.&q...
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Breakthrough in HIV/Cancer Treatment

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Graham and Hayes' Blog Post #2 Powerpoint

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Breakthrough in HIV/Cancer Treatment

  1. 1. Breakthrough In HIV/Cancer <ul><li>Graham and Hayes Blog Assignment #2 </li></ul>
  2. 2. What’s the breakthrough? <ul><li>Molecules called &quot; a ntibody- r ecruiting m olecule targeting H IV&quot; (ARM-H) </li></ul><ul><li>Molecules called &quot; a ntibody- r ecruiting m olecule targeting p rostate cancer&quot; (ARM-P) </li></ul><ul><li>Bind to certain proteins on antibodies and on HIV or Cancer Infected Cells </li></ul>
  3. 3. How does it work? <ul><li>The ARMs coat these antibodies </li></ul><ul><li>The cells are flagged as threat to body </li></ul><ul><li>Triggers a response by the immune system </li></ul>
  4. 4. Why is this a breakthrough? <ul><li>&quot;Instead of trying to kill the pathogens directly, these molecules manipulate our immune system to do something it wouldn't ordinarily do,&quot; David Spiegel, Ph.D., M.D. </li></ul><ul><li>Current treatment options for HIV and prostate cancer -- including antiviral drugs, radiation and chemotherapy -- involve severe side effects and are often ineffective against advanced cases. </li></ul><ul><li>ARM-H and ARM-P molecules, which the team has begun testing in mice, are structurally simple, inexpensive to produce, and could in theory be taken in pill form </li></ul>
  5. 5. Significance <ul><li>These new antibody triggers are just now only being tested on mice. </li></ul><ul><li>If proven to be effective for humans, these ARMs could provide some sort of alternative, cheaper, and less destructive form of treatment for two of the most devastating diseases humankind faces. </li></ul>
  6. 6. Sources Cited <ul><li>Yale University. &quot;New Synthetic Molecules Trigger Immune Response To HIV And Prostate Cancer.&quot; ScienceDaily 8 November 2009. 9 November 2009 < http://www.sciencedaily.com­ /releases/2009/11/091105165527.htm >. </li></ul>

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