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Biology of cancer

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Biology of cancer

  1. 1. The Biology of Cancer (pg 12)
  2. 2. The Biology of Cancer (pg 12)• Cancer = uncontrolled cell division
  3. 3. The Biology of Cancer (pg 12)• Cancer = uncontrolled cell division• Cells divide through a process called mitosis
  4. 4. The Biology of Cancer (pg 12)• Cancer = uncontrolled cell division• Cells divide through a process called mitosis• Normally, cells undergo mitosis only when necessary (to replace old cells, during growth, etc.)
  5. 5. The Biology of Cancer (pg 12)• Cancer = uncontrolled cell division• Cells divide through a process called mitosis• Normally, cells undergo mitosis only when necessary (to replace old cells, during growth, etc.)• In cancer, cells divide constantly, forming a large mass (tumor) that disrupts other organs
  6. 6. Mutations and Cancer• There are multiple genes that serve as “checkpoints” that prevent cells from dividing
  7. 7. Mutations and Cancer• There are multiple genes that serve as “checkpoints” that prevent cells from dividing• Over time, people accumulate mutations in their DNA from copying errors and mutagens
  8. 8. Mutations and Cancer• There are multiple genes that serve as “checkpoints” that prevent cells from dividing• Over time, people accumulate mutations in their DNA from copying errors and mutagens• If a person develops mutations in all of the “checkpoint” genes then they will get cancer
  9. 9. Mutations and Cancer• There are multiple genes that serve as “checkpoints” that prevent cells from dividing• Over time, people accumulate mutations in their DNA from copying errors and mutagens• If a person develops mutations in all of the “checkpoint” genes then they will get cancer• Therefore, cancer is more common in older people (children with cancer often have defective “proofreading” enzymes)

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