Lecture9 cns

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Lecture9 cns

  1. 1. THE CENTRAL NERVOUS SYSTEM CNS
  2. 2. DIVISION OF NERVOUS SYSTEM CENTRAL NERVOUS SYSTEM (CNS)  BRAIN    TELENCEPHALON DIENCEPHALON MESENCEPHALON (MIDBRAIN) RHOMBENCEPHALON (HINDBRAIN)     PROENCEPHALON (FOREBRAIN)   PERIPHERIAL NERVOUS SYSTEM (PNS) METENCEPHALON MYELENCEPHALON SPINAL CORD SOMATIC (SNS)     NERVES GANGLIA PLEXUSES AUTONOMIC (ANS)    NERVES GANGLIA PLEXUSES
  3. 3. BRAIN DIVISION CEREBRUM CEREBELLUM BRAIN STEM     DIENCEPHALON MESENCEPHALON PONS MYELENCEPHALON
  4. 4. DEVELOPMENT OF CNS NEURAL PLATE (17th day) NEURAL GROOVE neurulation (18-21day) NEURAL TUBE & CREST (21st day) NEUROPORUS ANTERIOR (25th day)  NEUROPORUS POSTERIOR (28th day) 
  5. 5. HUMAN EMBRYO
  6. 6. NEURAL PLATE
  7. 7. NEURAL TUBE & CREST
  8. 8. TUBE & CREST
  9. 9. DEVELOPMENT OF CNS
  10. 10. DEVELOPMENT OF CNS
  11. 11. BRAIN DEVELOPMENT
  12. 12. ORIGIN OF THE BRAIN
  13. 13. CEREBRUM-CORTEX NEOCORTEX (Cerebral hemisheres)   6 layers perception, association, reacting PALEOCORTEX (Olfactory cortex)   3 layers smell perception, stereotypical sexual behaviour ARCHICORTEX (Hippocampus)   2-4 layers learning, memorizing
  14. 14. GENERAL ORGANIZATION OF CNS GRAY MATTER       NEURON BODIES DENDRITES INITIAL SEGMENT OF AXON (UNMIELINATED) PROTOPLASMATIC AND FIBROUS ASTROCYTES MICROGLIA CAPILARES WHITE MATTER       MIELINATED AXONS OLIGODENDROCYTES FIBROUS ASTROCYTES MICROGLIA CAPILARES NO ANY NEURON BODIES!
  15. 15. SCHEDULE OF GRAY&WHITE MATTER
  16. 16. GRAY MATTER
  17. 17. WHITE MATTER
  18. 18. GRAY&WHITE MATTER LOCALISTAION GRAY    CORTEX OF CEREBRUM AND CEREBELLUM BASAL NUCLEI, THALMUS, HYPOTHALMUS HORNS AND GRAY COMISSURES OF SPINAL CORD WHITE   TRACTS FUNICULES OF SPINAL CORD
  19. 19. TRANSVERSE SECTION OF BRAIN
  20. 20. NEOCORTEX MOTOR SENSORY ASSOCIATON
  21. 21. NEOCORTEX
  22. 22. NEOCORTEX
  23. 23. BRODMANN’S AREAS
  24. 24. AREAS OF BRODMANN
  25. 25. NEOCORTEX MOLECULAR OUTER GRANULAR PYRAMIDAL CELL INNER GRANULAR GANGLIONIC MULTIFORM
  26. 26. CEREBRUM CORTEX LAYERS
  27. 27. PYRAMIDAL CELLS
  28. 28. CEREBELLUM
  29. 29. CEREBELLAR CORTEX MOLECULAR LAYER PURKINJE CELL LAYER GRANULAR LAYER
  30. 30. CEREBELLUM CORTEX
  31. 31. PURKINJE CELL
  32. 32. SPINAL CORD
  33. 33. SPINAL CORD
  34. 34. SPINAL CORD HORNS    ANTERIOR LATERAL DORSAL GRAY COMMISURA FUNICULES    ANTERIOR LATERAL POSTERIOR
  35. 35. MENINGES
  36. 36. MENINGES DURA MATER ARACHNOID PIA MATER
  37. 37. CRANIAL MENINGES
  38. 38. CRANIAL MENINGES
  39. 39. SPINAL MENINGES
  40. 40. SPINAL MENINGES
  41. 41. ARACHNOID & PIA MATER
  42. 42. CEREBROSPINAL FLUID FUCTION PRODUCTION FLOW RESORPTION COMPOSITION
  43. 43. CHOROID PLEXUS
  44. 44. CSF - SECRETION CHOROID PLEXUS    LATERAL, 3-rd AND 4-th VENTRICULES losse connective tissue (pia mater) fenestrated capillares EPENDYMAL CELLS   cuboidal / collumnar ion-transporting
  45. 45. CHOROID PLEXUS
  46. 46. CSF VOLUMEN 135ml DAILY SECRETION 550ml FILS VENTRICLES, CENTRAL CANAL, SUBARACHNOIDAL AND PERIVASCULAR SPACE FUNCTION   ENVELOPES CNS WITH HYDROSTATIC COAT QUICK REGULATION OF ICP (INTRACRANIAL PREASURE)
  47. 47. CSF - RESORPTION ARACHNOID VILLI VENAS OF PIA MATTER INTO EPINEURUM OF CRANIAL NERVES
  48. 48. BLOOD-BRAIN BARIER FUNCTIONAL DEVICE PREVENTS UNCONTROLED PASSAGE OF SUBSTANCES PROTECT NEURONS
  49. 49. BBB ENDOTHELIAL CELLS   TIGHT JUNCTIONS ENZYMATIC SYSTEMS BASAL MEMBRANE PERIVASCULAR SPACE  MACROPGAGES AND MICROGLIA PERIVASCULAR GLIA MEMBRANE  FOOT-LIKE PROCESSES OF ASTROCYTES
  50. 50. BBB
  51. 51. ANS
  52. 52. ANS
  53. 53. sANS
  54. 54. pANS
  55. 55. ANS

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