G lobal  I nfectious  D isease and  E pidemiology  O nline  N etwork GIDEON By Abel Medhanie Gebreyesus Sunil Nair HINF623...
Important Facts <ul><li>345  Diseases </li></ul><ul><li>231  Countries </li></ul><ul><li>339  Drugs & Vaccines </li></ul><...
GIDEON <ul><li>Web-based  Infectious Disease Diagnosis computer program that constructs a  differential diagnosis [DD],  r...
GIDEON Users <ul><li>Emergency room  Physicians </li></ul><ul><li>Infectious Disease  Specialist </li></ul><ul><li>Public ...
Highlights <ul><li>Point-of-care </li></ul><ul><li>Current or up-to-date </li></ul><ul><li>Diagnosis, Treatment, teaching ...
GIDEON Modules <ul><li>Diagnosis  </li></ul><ul><ul><li>out put differential diagnosis </li></ul></ul><ul><ul><li>“ why no...
DIAGNOSIS
EPIDEMIOLOGY
THERAPY
MICROBIOLOGY
DEMO <ul><li>DIAGNOSTIC MODULE </li></ul><ul><li>EPIDEMIOLOGY MODULE </li></ul>
HOW GIDEON WORKS <ul><li>PROBABILISTIC SYSTEM </li></ul><ul><ul><li>BAYESIAN THEOREM </li></ul></ul><ul><li>MySQL  DATABAS...
GIDEON Model MEDICAL EXPERT KNOWLEDGE DATA BASE BAYESIAN NETWORK INFERENCE ENGINE USER  INTERFACE END USER
 
Bayesian Theorem <ul><li>Application in clinical decision making  </li></ul><ul><ul><li>estimate the probability of a part...
Comparison n=86, Accuracy of clinical diagnosis  33%  compared to Medical officers with 87% correct diagnosis.  DD, Update...
LIMITATIONS <ul><li>Accuracy </li></ul><ul><ul><li>Correct diagnosis listed down in order </li></ul></ul><ul><ul><ul><li>S...
Conclusion <ul><li>GIDEON  is an impressive tool in  infectious disease diagnosis  that uses the power of the  internet  t...
References <ul><li>Stephen A Berger GIDEON: a comprehensive Web-based resource for geographic medicine   Published: 22 Apr...
Upcoming SlideShare
Loading in …5
×

Healthcare Technology Assessment Gideon Presentation - Sunil Nair Health Informatics Dalhousie University

2,830 views

Published on

Published in: Health & Medicine
0 Comments
2 Likes
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total views
2,830
On SlideShare
0
From Embeds
0
Number of Embeds
8
Actions
Shares
0
Downloads
21
Comments
0
Likes
2
Embeds 0
No embeds

No notes for slide

Healthcare Technology Assessment Gideon Presentation - Sunil Nair Health Informatics Dalhousie University

  1. 1. G lobal I nfectious D isease and E pidemiology O nline N etwork GIDEON By Abel Medhanie Gebreyesus Sunil Nair HINF6230 – Technology Assessment
  2. 2. Important Facts <ul><li>345 Diseases </li></ul><ul><li>231 Countries </li></ul><ul><li>339 Drugs & Vaccines </li></ul><ul><li>1409 Microbes </li></ul><ul><li>35,800 References </li></ul><ul><li>16,228 Country Specific Notes </li></ul><ul><li>6,835 Disease outbreaks </li></ul><ul><li>4,205 Images and Maps </li></ul><ul><li>Source:www.ebscohost.com </li></ul>
  3. 3. GIDEON <ul><li>Web-based Infectious Disease Diagnosis computer program that constructs a differential diagnosis [DD], ranked in order of percent probability based on specific clinical data entered by user. </li></ul><ul><ul><li>Updated weekly </li></ul></ul><ul><ul><li>CD-ROM updated every month </li></ul></ul><ul><li>Developed in 1994, Proprietary – Subscription. </li></ul><ul><li>Used in 1500 Institutions worldwide </li></ul>
  4. 4. GIDEON Users <ul><li>Emergency room Physicians </li></ul><ul><li>Infectious Disease Specialist </li></ul><ul><li>Public Health Officials </li></ul><ul><li>Pediatricians </li></ul><ul><li>Medical Schools </li></ul><ul><li>Other Health care workers </li></ul>
  5. 5. Highlights <ul><li>Point-of-care </li></ul><ul><li>Current or up-to-date </li></ul><ul><li>Diagnosis, Treatment, teaching resource </li></ul><ul><li>Global </li></ul>
  6. 6. GIDEON Modules <ul><li>Diagnosis </li></ul><ul><ul><li>out put differential diagnosis </li></ul></ul><ul><ul><li>“ why not” </li></ul></ul><ul><li>Epidemiology </li></ul><ul><ul><li>Transmission, diagnosis and treatment </li></ul></ul><ul><ul><li>Country specific. </li></ul></ul><ul><li>Therapy </li></ul><ul><ul><li>Drugs, vaccines, interactions, adverse effects </li></ul></ul><ul><li>Microbiology </li></ul><ul><ul><li>Identify the Pathogen </li></ul></ul>
  7. 7. DIAGNOSIS
  8. 8. EPIDEMIOLOGY
  9. 9. THERAPY
  10. 10. MICROBIOLOGY
  11. 11. DEMO <ul><li>DIAGNOSTIC MODULE </li></ul><ul><li>EPIDEMIOLOGY MODULE </li></ul>
  12. 12. HOW GIDEON WORKS <ul><li>PROBABILISTIC SYSTEM </li></ul><ul><ul><li>BAYESIAN THEOREM </li></ul></ul><ul><li>MySQL DATABASES </li></ul><ul><li>WEB-INTERFACE USING PHP </li></ul>
  13. 13. GIDEON Model MEDICAL EXPERT KNOWLEDGE DATA BASE BAYESIAN NETWORK INFERENCE ENGINE USER INTERFACE END USER
  14. 15. Bayesian Theorem <ul><li>Application in clinical decision making </li></ul><ul><ul><li>estimate the probability of a particular diagnosis given specific signs, symptoms, or test outcomes. </li></ul></ul><ul><li>Sensitivity and Specificity </li></ul><ul><ul><li>Conditional Probability: given that test is +ve [-ve] then diagnosis is true [false] </li></ul></ul><ul><ul><li>Complexity of the Statistical inference depends on Specificity of the patient findings. </li></ul></ul>
  15. 16. Comparison n=86, Accuracy of clinical diagnosis 33% compared to Medical officers with 87% correct diagnosis. DD, Updated weekly. info on epidemiology, therapy and Microbiology GIDEON n=103, Accurately diagnosed 73% cases. Provides DD based on clinician entered Signs & Symptoms. Updated weekly. Dxplain n=295, Accurately diagnosed 75% cases. Clinical diagnosis listed in 94.7% cases. Provide DD, general info on pathogens and vaccines of Infectious Diseases Computer Program for Diagnosing and Teaching Geographic Medicine Evaluation* Purpose System Name
  16. 17. LIMITATIONS <ul><li>Accuracy </li></ul><ul><ul><li>Correct diagnosis listed down in order </li></ul></ul><ul><ul><ul><li>Study – correct diagnosis listed 69%; ranked first 60% of the time. </li></ul></ul></ul><ul><ul><li>Depends on Quality of input data </li></ul></ul><ul><ul><li>Presence of irrelevant data </li></ul></ul><ul><ul><li>Complex [co-morbid] cases </li></ul></ul><ul><li>Reliance on literature for data </li></ul><ul><ul><li>Delay in database update </li></ul></ul><ul><li>Not User Specific and area specific </li></ul>
  17. 18. Conclusion <ul><li>GIDEON is an impressive tool in infectious disease diagnosis that uses the power of the internet to provide access to and presentation of data to the infectious disease community. </li></ul><ul><li>There is need for further evaluation with regards to accuracy </li></ul><ul><li>Probably have separate versions focusing the specific user groups. </li></ul>
  18. 19. References <ul><li>Stephen A Berger GIDEON: a comprehensive Web-based resource for geographic medicine Published: 22 April 2005 International Journal of Health Geographics 2005, 4 :10 </li></ul><ul><li>Stephen C. Edberg , Global Infectious Diseases and Epidemiology Network (GIDEON): A World Wide Web–Based Program for Diagnosis and Informatics in Infectious Diseases, Clinical Infectious Diseases 2005;40:123–126 </li></ul><ul><li>Dena M. Bravata et al., Evaluating Detection and Diagnostic Decision Support Systems for Bioterrorism Response. Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 10, No. 1, January 2004 </li></ul><ul><li>Global Infectious Diseases and Epidemiology Network (GIDEON) Julia Kulla-Mader INLS 279: Bioinformatics Research Review 2006-04-12 </li></ul><ul><li>Use of the Computer Program GIDEON at an Inpatient Infectious Diseases Consultation Service Robert F. Luo and John G. Bartlett Clinical Infectious Diseases 2006; 42:157–7 _ 2005 </li></ul>

×