LEPTIN & OBESITYDr. Smrutiranjan Patanaik
   OBESITY – A GLOBAL HEALTH PROBLEM   RECENT LIPOSTATIC HYPOTHESIS HAS GIVEN    ATTENTION TO LEPTIN   DEFECTIVE OB/OB ...
   A PEPTIDE HORMONE   167 AMINO ACIDS   M.wt. 16kDa   SECRETED BY    ADIPOCYTES   DISCOVERED BY    FRIEDMAN IN 1994
   LEPTIN OPERATES AS PART OF A FEEDBACK    LOOP BY WHICH THE SIZE OF THE BODY FAT    DEPOTS CAN OPERATE THROUGH A HUMORA...
THANK YOU
Leptin and obesity cycle
Leptin and obesity cycle
Leptin and obesity cycle
Leptin and obesity cycle
Leptin and obesity cycle
Leptin and obesity cycle
Leptin and obesity cycle
Leptin and obesity cycle
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Leptin and obesity cycle

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How fat is managed in our human body , and how by altering the leptin pathway we can treat bulimia, anorexia and obesity like disorders.

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Leptin and obesity cycle

  1. 1. LEPTIN & OBESITYDr. Smrutiranjan Patanaik
  2. 2.  OBESITY – A GLOBAL HEALTH PROBLEM RECENT LIPOSTATIC HYPOTHESIS HAS GIVEN ATTENTION TO LEPTIN DEFECTIVE OB/OB GENE IN MICE REVEALS ASSOCIATION OF LEPTIN WITH OBESITY KNOCKOUT OF DB/DB GENE PRODUCES DECREASE IN LEPTIN RECEPTORS LEPTIN RESISTANCE IS ASSOCIATED WITH OBESITY
  3. 3.  A PEPTIDE HORMONE 167 AMINO ACIDS M.wt. 16kDa SECRETED BY ADIPOCYTES DISCOVERED BY FRIEDMAN IN 1994
  4. 4.  LEPTIN OPERATES AS PART OF A FEEDBACK LOOP BY WHICH THE SIZE OF THE BODY FAT DEPOTS CAN OPERATE THROUGH A HUMORAL LINK TO REGULATE FOOD INTAKE
  5. 5. THANK YOU

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