Dr.Prof.P.Vijayaragavan unit. Dr. A.Vijayalakshmi. M7 unit .
 
<ul><li>Mr.Kuppusamy,.55 years male </li></ul><ul><li>Admitted with the complaints of coughing of blood for 4 days. </li><...
<ul><li>There was no h/o PND,Orthopnea. </li></ul><ul><li>No h/o chest pain,no h/o wheeze, </li></ul><ul><li>No h/o fever ...
<ul><li>On General examinations ; </li></ul><ul><li>Patient is conscious </li></ul><ul><li>Oriented.Afebrile.Tachypnea pre...
<ul><li>Respiratory system ; </li></ul><ul><li>Inspection </li></ul><ul><li>Trachea seems to be in the midline. </li></ul>...
<ul><li>Palpation ; </li></ul><ul><li>Trachea is in the midline.  </li></ul><ul><li>Movements of chest wall is equal. </li...
<ul><li>CNS  Examination- </li></ul><ul><li>NFND. </li></ul><ul><li>I MPRESSION -? Pulmonary Tuberculosis. </li></ul><ul><...
<ul><li>INVESTIGATIONS ; </li></ul><ul><li>HB- 10gm% </li></ul><ul><li>TC-7600 </li></ul><ul><li>P50, L42 </li></ul><ul><l...
<ul><li>Chest clinic- </li></ul><ul><li>Sputum c/s –negative. </li></ul><ul><li>Sputum for AFB negative. </li></ul><ul><li...
 
 
 
 
<ul><li>Following that MRI was taken Which shows ….., </li></ul>
 
 
 
 
<ul><li>Lipid profile- </li></ul><ul><li>Total cholestrol 180mg/dl </li></ul><ul><li>Tg-139 </li></ul><ul><li>HDL 26 </li>...
<ul><li>LFT- </li></ul><ul><li>Total bilirubin-0.8mg </li></ul><ul><li>SGOT-32 IU </li></ul><ul><li>SGPT-27 IU </li></ul><...
<ul><li>Echocardiography; </li></ul><ul><li>Normal LV function. </li></ul><ul><li>No RWMA. </li></ul><ul><li>Normal valves...
<ul><li>Final Diagnosis </li></ul><ul><li>Aneurysm of Descending aorta, leaking into left lung and pleural cavity presenti...
<ul><li>Thoracic Aortic Aneurysm . </li></ul><ul><li>It is less common than abdominal aortic aneurysm. </li></ul><ul><li>C...
<ul><li>Thoracic aortic aneurysm is common in white race. </li></ul><ul><li>Sex; Men affected more than women 2 to 3 times...
<ul><li>Etiology - </li></ul><ul><li>1.Atherosclerosis-very common. </li></ul><ul><li>2.Connective tissue disorders.(Takay...
 
<ul><li>Pathophysiology- </li></ul><ul><li>Degenerative changes in the wall of the aorta lead to cystic medial necrosis. T...
<ul><li>In Marfans syndrome fibrillin gene mutation  is responsible for this structural lipoprotein changes causing dilata...
 
 
<ul><li>Clinical manifestations- </li></ul><ul><li>Mostly asymptomatic. </li></ul><ul><li>If symptoms occurs ,it may be du...
<ul><li>Compression of recurrent laryngeal nerve causing hoarseness of voice. </li></ul><ul><li>Vascular consequences incl...
<ul><li>Angina sometimes occurs in one quarter of patients due to direct compressions of intra thoracic structures or eros...
<ul><li>X-Ray chest-  Mediastinal widening . </li></ul><ul><li>CT -Less accurate . </li></ul><ul><li>MRI -Very accurately ...
<ul><li>CONTRAST AORTOGRAPHY is the best investigation for Aneurysm of aorta . </li></ul>
<ul><li>Medical; </li></ul><ul><li>Long term Beta blocker therapy.And control of hypertension. </li></ul><ul><li>Surgica l...
<ul><li>Surgical repair with synthetic graft or own blood vessel graft can be done. </li></ul><ul><li>Endovascular stent g...
 
 
 
 
 
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An Interesting Case Of Hemoptysis

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An Interesting Case Of Hemoptysis

  1. 1. Dr.Prof.P.Vijayaragavan unit. Dr. A.Vijayalakshmi. M7 unit .
  2. 3. <ul><li>Mr.Kuppusamy,.55 years male </li></ul><ul><li>Admitted with the complaints of coughing of blood for 4 days. </li></ul><ul><li>H/o present illness ; </li></ul><ul><li>He had 4 days of hemoptysis which was large in quantity around 5 glasses on the day of admission. </li></ul><ul><li>H/o dry cough present 4 days. </li></ul><ul><li>H/o breathing difficulty present for 4 days </li></ul><ul><li>H/o giddiness present for 4 days. </li></ul><ul><li>H/o loss of weight and loss of appetite present for 3 months. </li></ul>
  3. 4. <ul><li>There was no h/o PND,Orthopnea. </li></ul><ul><li>No h/o chest pain,no h/o wheeze, </li></ul><ul><li>No h/o fever . </li></ul><ul><li>Past history ; </li></ul><ul><li>3 months back he had one bout of heamoptysis ,for which he was treated in a private hospital conservatively.The details not available. </li></ul><ul><li>No h/oT.B, Asthma, DM, HT, Epilepsy. </li></ul><ul><li>Personal history; Smoking for 25 years. Consumes alcohol, Chewing tobacco and pan, mixed diet . </li></ul><ul><li>Family history-Nil relevent. </li></ul>
  4. 5. <ul><li>On General examinations ; </li></ul><ul><li>Patient is conscious </li></ul><ul><li>Oriented.Afebrile.Tachypnea present. </li></ul><ul><li>Clubbing present. </li></ul><ul><li>No cyanosis ,no pedal oedema, not icteric, </li></ul><ul><li>RR rate 28/min. </li></ul><ul><li>Pulse;82/min. </li></ul><ul><li>BP;110/70 mm of Hg. </li></ul><ul><li>CVS.-S1, S2 heard. No murmur . </li></ul>
  5. 6. <ul><li>Respiratory system ; </li></ul><ul><li>Inspection </li></ul><ul><li>Trachea seems to be in the midline. </li></ul><ul><li>Apical impulse in the 5 th ICS. </li></ul><ul><li>Symmetrical chest wall. </li></ul><ul><li>No scoliosis, no Kyphosis. </li></ul><ul><li>Movements of chest wall equal. </li></ul>
  6. 7. <ul><li>Palpation ; </li></ul><ul><li>Trachea is in the midline. </li></ul><ul><li>Movements of chest wall is equal. </li></ul><ul><li>Percussion </li></ul><ul><li>Equal resonant note in all the area. </li></ul><ul><li>Auscultation;NVBS+ </li></ul><ul><li>Abdomen examination </li></ul><ul><li>Soft. </li></ul><ul><li>No organomegaly . </li></ul>
  7. 8. <ul><li>CNS Examination- </li></ul><ul><li>NFND. </li></ul><ul><li>I MPRESSION -? Pulmonary Tuberculosis. </li></ul><ul><li>To rule out Cardiac cause for hemoptysis . </li></ul>
  8. 9. <ul><li>INVESTIGATIONS ; </li></ul><ul><li>HB- 10gm% </li></ul><ul><li>TC-7600 </li></ul><ul><li>P50, L42 </li></ul><ul><li>ESR- 12/26 </li></ul><ul><li>Pcv-30 </li></ul><ul><li>Platelets- 2.6 lakhs </li></ul><ul><li>MCV-87.2 </li></ul><ul><li>MCH24 </li></ul><ul><li>MCHC-32.4 </li></ul><ul><li>Urea-25 </li></ul><ul><li>Creatinine-1.1 </li></ul>
  9. 10. <ul><li>Chest clinic- </li></ul><ul><li>Sputum c/s –negative. </li></ul><ul><li>Sputum for AFB negative. </li></ul><ul><li>Mantoux test -10 mm induration. </li></ul><ul><li>X-Ray chest-slight mediastinal widening. </li></ul><ul><li>ECG –WNL. </li></ul><ul><li>PLANNED FOR CT . </li></ul>
  10. 15. <ul><li>Following that MRI was taken Which shows ….., </li></ul>
  11. 20. <ul><li>Lipid profile- </li></ul><ul><li>Total cholestrol 180mg/dl </li></ul><ul><li>Tg-139 </li></ul><ul><li>HDL 26 </li></ul><ul><li>LDL 71 </li></ul><ul><li>VLDL27 </li></ul><ul><li>CRP-POITIVE 24mg </li></ul><ul><li>VDRL-NR </li></ul>
  12. 21. <ul><li>LFT- </li></ul><ul><li>Total bilirubin-0.8mg </li></ul><ul><li>SGOT-32 IU </li></ul><ul><li>SGPT-27 IU </li></ul><ul><li>Alkaline phosphate-31 </li></ul><ul><li>Protein 5.9 </li></ul><ul><li>Albumin 3.6 </li></ul>
  13. 22. <ul><li>Echocardiography; </li></ul><ul><li>Normal LV function. </li></ul><ul><li>No RWMA. </li></ul><ul><li>Normal valves. </li></ul><ul><li>Descending thoracic Aorta aneurysm 5.3 cm in size. </li></ul>
  14. 23. <ul><li>Final Diagnosis </li></ul><ul><li>Aneurysm of Descending aorta, leaking into left lung and pleural cavity presenting as hemoptysis . </li></ul>
  15. 24. <ul><li>Thoracic Aortic Aneurysm . </li></ul><ul><li>It is less common than abdominal aortic aneurysm. </li></ul><ul><li>Classification- </li></ul><ul><li>Ascending Aortic aneurysm </li></ul><ul><li>Arch of aorta </li></ul><ul><li>Descending aorta. </li></ul>
  16. 25. <ul><li>Thoracic aortic aneurysm is common in white race. </li></ul><ul><li>Sex; Men affected more than women 2 to 3 times. </li></ul><ul><li>Age –at diagnosis the patient ‘s age may be in 60 to 70 years as it is mostly asymtomatic. </li></ul><ul><li>In atherosclerosis it can occur at 40 to 50 years. </li></ul>
  17. 26. <ul><li>Etiology - </li></ul><ul><li>1.Atherosclerosis-very common. </li></ul><ul><li>2.Connective tissue disorders.(Takayasu’s aortitis,Rheumatoid arthritis) </li></ul><ul><li>3.Marfans syndrome. </li></ul><ul><li>4.Ehlers –Danlos syndrome. </li></ul><ul><li>5.Syphilis. </li></ul><ul><li>6.Infectious Aortitis. </li></ul><ul><li>7.TB can sometimes lead to thoracic aortic aneurysm. </li></ul>
  18. 28. <ul><li>Pathophysiology- </li></ul><ul><li>Degenerative changes in the wall of the aorta lead to cystic medial necrosis. This causes damage to collagen and elastin, loss of smooth muscle cells and increased amounts of basophilic ground substance in the medial (elastic) layer of the aorta. The ascending TAA is usually more affected by cystic medial necrosis. Descending aortic aneurysm is a primary consequence of Atherosclerosis . </li></ul>
  19. 29. <ul><li>In Marfans syndrome fibrillin gene mutation is responsible for this structural lipoprotein changes causing dilatation of aortic wall. </li></ul><ul><li>75% of bicuspid aortic valve have evidence of cystic medial necrosis. </li></ul><ul><li>Usually aneurysms of Fusiform nature is true aneurysm .In this all the layer of aorta is involved. </li></ul><ul><li>In pseudoaneurysm-saccular type a small blister or bleb present on the side of aorta . </li></ul>
  20. 32. <ul><li>Clinical manifestations- </li></ul><ul><li>Mostly asymptomatic. </li></ul><ul><li>If symptoms occurs ,it may be due to copression of trachea causing wheezing, dyspnea, cough, hemoptysis, or recurrent pneumonitis. </li></ul><ul><li>Compression of esophagus causes dysphagia . </li></ul>
  21. 33. <ul><li>Compression of recurrent laryngeal nerve causing hoarseness of voice. </li></ul><ul><li>Vascular consequences include aortic regurgitations due to dilatation of aortic root,Thromboembolism causing stroke, lower extremity ischemia, renal infarctions, or mesenteric ischemia also can occur . </li></ul>
  22. 34. <ul><li>Angina sometimes occurs in one quarter of patients due to direct compressions of intra thoracic structures or erosions into bones.Typicaly the pain is steady, deep, boring and at times severe . </li></ul>
  23. 35. <ul><li>X-Ray chest- Mediastinal widening . </li></ul><ul><li>CT -Less accurate . </li></ul><ul><li>MRI -Very accurately detect and size thoracic aneurysms. </li></ul><ul><li>Transthoracic aorta is an excellent modality for imaging the aortic root. </li></ul><ul><li>Trans esophageal echo is an excellent for Visualization for entire aorta. Not usually done because of it semi invasive nature . </li></ul>
  24. 36. <ul><li>CONTRAST AORTOGRAPHY is the best investigation for Aneurysm of aorta . </li></ul>
  25. 37. <ul><li>Medical; </li></ul><ul><li>Long term Beta blocker therapy.And control of hypertension. </li></ul><ul><li>Surgica l- </li></ul><ul><li>Operative repair with placement of prosthetic graft is indicated in patients with symptomatic thoracic aortic aneurysm and in patients with aortic diameter of >5.5 to6 cm or has increasing by>1cm per year . </li></ul>
  26. 38. <ul><li>Surgical repair with synthetic graft or own blood vessel graft can be done. </li></ul><ul><li>Endovascular stent graft can be done. </li></ul><ul><li>Prevention of aneurysm – </li></ul><ul><li>1.stop smoking. </li></ul><ul><li>2.BP control. </li></ul><ul><li>3.Exercise. </li></ul><ul><li>4.Healthy weight. </li></ul><ul><li>5.Eat healthier diet. </li></ul>

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