Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.

Comparison of Small Molecule Drugs and Biologic Products


Published on

Recent surveys indicate that physicians in the US and Europe are still unclear on what a biosimilar is – even those physicians who prescribe biologic medicines. See the infographic for a deeper look at the differences between biosimilar and generic medicines.

Get the latest on Biosimilars at
Curated resources updated daily.

  • I am a living proof that Chief Dr Lebo herbal WORKS and can be incredibly useful to couples with infertility issues. My husband and I found out I was pregnant after over 6 years of desperately trying. We were both checked but the doctors could find nothing. I prayed and prayed, Fasted but nothing happened. I ordered for Chief Dr Lebo herbal medication after hearing numerous success stories of other women using his recommendations. As soon as I started implementing the instructions, including doing some acupuncture with his guidance, I could see a dramatic improvement of my health within days and within 2 months we had a new little one on the way! I have gone through years of disappointment never believing it could happen to. It did. All thanks to Chief Dr. Lebo Contact Chief Dr Lebo on via Email: or Call & WhatsApp+27631394550
    Are you sure you want to  Yes  No
    Your message goes here

Comparison of Small Molecule Drugs and Biologic Products

  1. 1. Small Molecular Weight Manufacturing Size Structure Manufacturing Quality Tests Approval Requirements Mode of Administration Large 4,000 to > 140,000 Daltons < 500 - 900 Daltons Complex with potential structural variations Simple and well defined Specialized biological process to make similar copy Predictable chemical process to make identical copy ≥ 250 ≤ 50 Large clinical trials in patients Usually requires injection or infusion Small clinical trials in healthy volunteers Usually amenable to ingestion VSBIOSIMILARS GENERICS Comparison of Traditional Small Molecule Drugs and Biologic Agents Immunogenic Stable Chemical Non Immunogenic Unstable Protein Comparison of Traditional Small Molecule Drugs and Biologic Agents 1. Biosimilars Versus Generics. 2015. Available at: Accessed April 27, 2015. 2. Understanding Key Differences Between Biosimilars And Small Molecule Generics. 1st ed. New York City: McMahon; 2013:8.