The Physiology of High Altitude Exposure
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the physiology of high altitude exposure. Learning objectives: 1. Explain the change in composition of air at high altitude and the effects of low oxygen pressure on the body 2. Discuss the change of alveolar PO2 at different elevations 3. Explain the mechanisms and principles of acclimatization of the body to low O2 4. Identify and explain the causes of natural acclimatization in natives of High altitude 5. Explain the causes & clinical features of Acute Mountain Sickness (AMS), High Altitude Pulmonary Edema (HAPE), & High Altitude Cerebral Edema (HACE) 6. Identify various treatment modalities for Acute Mountain Sickness 7. Explain the causes & clinical features of Chronic Mountain Sickness (CMS) Study Resources: 1. Chapter 44, Guyton and Hall Textbook of Medical Physiology, 14th edition 2. Chapter 34 and 35, Ganong’s Review of Medical Physiology, 26th edition 3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition 4. Chapter 9, West’s Respiratory Physiology, 10th edition 5. The Physiology of High-Altitude Exposure: https://www.ncbi.nlm.nih.gov/books/NBK232874/
