SlideShare a Scribd company logo
Systemic Inflammatory Response Syndrome (SIRS)   Prognosis   www.ipgdx.com
Systemic Inflammatory Response Syndrome  (SIRS)  is an inflammatory state affecting the whole body, frequently in response to infection.   www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS
SIRS is nonspecific  and not always related to infection. It is related to  Sepsis ,a condition in which individuals both meet criteria for  SIRS  and have a known or highly suspected infection.   www.ipgdx.com INFECTION SIRS SEPSIS Phase Angle a Prognostic Factor for Survival in SIRS
SIRS  is defined as 2 or more of the following variables: Fever of more than 38°C or less than 36°C Heart rate of more than 90 beats per minute Respiratory rate of more than 20 breaths per minute or a PaCO2 level of less than 32 mm Hg Abnormal white blood cell count (>12,000/µL or <4,000/µL or >10% bands)   www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS
SIRS  is one of several conditions related to systemic inflammation, organ dysfunction, and organ failure.  www.ipgdx.com SIRS Pancreatitis Trauma Burns Bacteraemia Irradiation ?? Infection Phase Angle a Prognostic Factor for Survival in SIRS
Leucocytes Endothelial cells Complement Plasmatic hemocoagulation system Platelets www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS
The causes of SIRS are broadly classified as  infectious  or  noninfectious.  www.ipgdx.com Causes:   When  SIRS  is due to an infection, it is considered  sepsis.   Noninfectious causes of  SIRS  include trauma, burns, pancreatitis, ischemia and haemorrhage.   Phase Angle a Prognostic Factor for Survival in SIRS
Septic shock is severe sepsis with hypo tension (systolic BP < 90mmHg) despite adequate fluid resuscitation or the requirement for vasopressors/inotropes to maintain blood pressure.   www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS
Here is an excerpt  of the clinical observation study   from  23rd International Symposium on Intensive Care and Emergency Medicine.  www.ipgdx.com It was concluded from the study that phase Angle acts as a predictor for survival in patients with  SIRS .   Phase Angle a Prognostic Factor for Survival in SIRS
PrognostiCheck ®  for prognosis based upon a noninvasive diagnostic test  measures the resistance,reactance and phase angle (in degrees).A low phase angle has been associated with an altered cellular membrane function.  www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS
www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS Tests were conducted on 30 consecutive  patients( 11 female, 19 male ,median age of 67 [ 16.5 ] years ) after admitting them to the  intensive care unit ,all of whom met 2 or more  SIRS  Criteria.
In Septic shock patients,a phase angle of less than 4 degree has been reported to be associated with increases mortality.  www.ipgdx.com Severity of the illness was characterized according to APACHE II(Acute Physiology and Chronis Health Evaluation)  Phase Angle a Prognostic Factor for Survival in SIRS
Non-invasive impedance analysis was performed using a tetra-polar hand-to-foot measuring device and derived phase angle was calculated as arc tan (reactance/resistance).  www.ipgdx.com increasing  Reactance (  )‏ Phase Angle a Prognostic Factor for Survival in SIRS
All measurements were performed in the supine position of the patient with special care.  www.ipgdx.com After 28 days, out of the 30 patients  investigated, 10 had died and 20 survived.  In seven out of 20 survivors,a phase angle of more than 4 degree was measured on the first  day study,whereas in all patients who died,the  phase angle was less than 4 degree (P=0.038)  Phase Angle a Prognostic Factor for Survival in SIRS
The conclusion was that an initial phase angle of more than 4 degree may be correlated with survival,in patients suffering with SIRS.  www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS
www.ipgdx.com [email_address] By  IPGDx, LLC [email_address] For more information or inquiries regarding direct investments,  collaborative product development and  partnerships please contact below.  PrognostiCheck R

More Related Content

Viewers also liked

Multiple Organ Dysfunction Syndrome2009
Multiple Organ Dysfunction Syndrome2009Multiple Organ Dysfunction Syndrome2009
Multiple Organ Dysfunction Syndrome2009
Deep Deep
 
Sepsis
SepsisSepsis
Sepsis 2016
Sepsis 2016 Sepsis 2016
Sepsis 2016
Subhankar Chatterjee
 
Strategizing SIRS in nutrition
Strategizing SIRS in nutritionStrategizing SIRS in nutrition
Strategizing SIRS in nutrition
tcrumph2
 
What, why & how of SIRs in india
What, why & how of SIRs in indiaWhat, why & how of SIRs in india
What, why & how of SIRs in india
Vishal Dedhia
 
Septic shock sirs and mof
Septic shock  sirs and mofSeptic shock  sirs and mof
Septic shock sirs and mof
Osama Omar
 
Inflammation
Inflammation Inflammation
Inflammation
drsapnaharsha
 
Acute inflammation
Acute inflammationAcute inflammation
Acute inflammation
Dr. Varughese George
 
sepsis
 sepsis sepsis
Introduction to Sepsis
Introduction to SepsisIntroduction to Sepsis
Introduction to Sepsis
Hatem Soliman Aboumarie
 
Anesthesia for tracheoesophageal fistula
Anesthesia for tracheoesophageal fistulaAnesthesia for tracheoesophageal fistula
Anesthesia for tracheoesophageal fistula
Hazem Sharaf
 
Sedation practices in ICU
Sedation practices in ICUSedation practices in ICU
Sedation practices in ICU
Abhijit Nair
 
Sepsis
SepsisSepsis
Chronic Renal Disease (CKD)
Chronic Renal Disease (CKD)Chronic Renal Disease (CKD)
Chronic Renal Disease (CKD)
Janelyn Ong
 
liver Bilirubin Metabolism Physiological Jaundice
liver Bilirubin Metabolism Physiological Jaundice liver Bilirubin Metabolism Physiological Jaundice
liver Bilirubin Metabolism Physiological Jaundice
Rajendran Surendran
 
Toxic shock syndrome
Toxic shock syndromeToxic shock syndrome
Toxic shock syndrome
jasleenbrar03
 
Perioperative acute kidney injury
Perioperative acute kidney injuryPerioperative acute kidney injury
Perioperative acute kidney injury
Andrew Ferguson
 
Toxic shock syndrome
Toxic shock syndromeToxic shock syndrome
Toxic shock syndrome
Babak Jebelli
 
Acute Kidney Injury in the Cardiac Surgery Patient
Acute Kidney Injury in the Cardiac Surgery PatientAcute Kidney Injury in the Cardiac Surgery Patient
Acute Kidney Injury in the Cardiac Surgery Patient
Hofstra Northwell School of Medicine
 
Congestive cardiac failure diagnosis and treatment
Congestive cardiac failure diagnosis and treatmentCongestive cardiac failure diagnosis and treatment
Congestive cardiac failure diagnosis and treatment
Smilu Mohanlal
 

Viewers also liked (20)

Multiple Organ Dysfunction Syndrome2009
Multiple Organ Dysfunction Syndrome2009Multiple Organ Dysfunction Syndrome2009
Multiple Organ Dysfunction Syndrome2009
 
Sepsis
SepsisSepsis
Sepsis
 
Sepsis 2016
Sepsis 2016 Sepsis 2016
Sepsis 2016
 
Strategizing SIRS in nutrition
Strategizing SIRS in nutritionStrategizing SIRS in nutrition
Strategizing SIRS in nutrition
 
What, why & how of SIRs in india
What, why & how of SIRs in indiaWhat, why & how of SIRs in india
What, why & how of SIRs in india
 
Septic shock sirs and mof
Septic shock  sirs and mofSeptic shock  sirs and mof
Septic shock sirs and mof
 
Inflammation
Inflammation Inflammation
Inflammation
 
Acute inflammation
Acute inflammationAcute inflammation
Acute inflammation
 
sepsis
 sepsis sepsis
sepsis
 
Introduction to Sepsis
Introduction to SepsisIntroduction to Sepsis
Introduction to Sepsis
 
Anesthesia for tracheoesophageal fistula
Anesthesia for tracheoesophageal fistulaAnesthesia for tracheoesophageal fistula
Anesthesia for tracheoesophageal fistula
 
Sedation practices in ICU
Sedation practices in ICUSedation practices in ICU
Sedation practices in ICU
 
Sepsis
SepsisSepsis
Sepsis
 
Chronic Renal Disease (CKD)
Chronic Renal Disease (CKD)Chronic Renal Disease (CKD)
Chronic Renal Disease (CKD)
 
liver Bilirubin Metabolism Physiological Jaundice
liver Bilirubin Metabolism Physiological Jaundice liver Bilirubin Metabolism Physiological Jaundice
liver Bilirubin Metabolism Physiological Jaundice
 
Toxic shock syndrome
Toxic shock syndromeToxic shock syndrome
Toxic shock syndrome
 
Perioperative acute kidney injury
Perioperative acute kidney injuryPerioperative acute kidney injury
Perioperative acute kidney injury
 
Toxic shock syndrome
Toxic shock syndromeToxic shock syndrome
Toxic shock syndrome
 
Acute Kidney Injury in the Cardiac Surgery Patient
Acute Kidney Injury in the Cardiac Surgery PatientAcute Kidney Injury in the Cardiac Surgery Patient
Acute Kidney Injury in the Cardiac Surgery Patient
 
Congestive cardiac failure diagnosis and treatment
Congestive cardiac failure diagnosis and treatmentCongestive cardiac failure diagnosis and treatment
Congestive cardiac failure diagnosis and treatment
 

More from IPGDx LLC

Adenocarcinoma Prognosis
Adenocarcinoma PrognosisAdenocarcinoma Prognosis
Adenocarcinoma Prognosis
IPGDx LLC
 
Mesothelioma Prognosis
Mesothelioma PrognosisMesothelioma Prognosis
Mesothelioma Prognosis
IPGDx LLC
 
Breast Cancer Prognosis
Breast Cancer Prognosis Breast Cancer Prognosis
Breast Cancer Prognosis
IPGDx LLC
 
IPGDx EFresh
IPGDx EFreshIPGDx EFresh
IPGDx EFresh
IPGDx LLC
 
Prognosti Check Phase Angle Bibliography
Prognosti Check Phase Angle BibliographyPrognosti Check Phase Angle Bibliography
Prognosti Check Phase Angle Bibliography
IPGDx LLC
 
Lung Cancer prognosis
Lung Cancer prognosisLung Cancer prognosis
Lung Cancer prognosis
IPGDx LLC
 
Food Safety
Food SafetyFood Safety
Food Safety
IPGDx LLC
 
PrognostiCheck® Value Proposition Strategy and Focus.
PrognostiCheck® Value Proposition Strategy and Focus.PrognostiCheck® Value Proposition Strategy and Focus.
PrognostiCheck® Value Proposition Strategy and Focus.
IPGDx LLC
 
PrognostiCheck® device measures prognosis. Reliable, Objective and Noninvasive.
PrognostiCheck® device measures prognosis. Reliable, Objective and Noninvasive.PrognostiCheck® device measures prognosis. Reliable, Objective and Noninvasive.
PrognostiCheck® device measures prognosis. Reliable, Objective and Noninvasive.
IPGDx LLC
 
EFresh(R) device measures food freshness, juiciness and food quality.
EFresh(R) device measures food freshness, juiciness and food quality.EFresh(R) device measures food freshness, juiciness and food quality.
EFresh(R) device measures food freshness, juiciness and food quality.
IPGDx LLC
 
E Fresh Beef Tenderness
E Fresh Beef TendernessE Fresh Beef Tenderness
E Fresh Beef Tenderness
IPGDx LLC
 
PrognostiCheck ® - The Biological Compass
PrognostiCheck ® - The Biological CompassPrognostiCheck ® - The Biological Compass
PrognostiCheck ® - The Biological Compass
IPGDx LLC
 
Efresh
EfreshEfresh
Efresh
IPGDx LLC
 
Tim Thesis
Tim ThesisTim Thesis
Tim Thesis
IPGDx LLC
 
Prognosti Check
Prognosti CheckPrognosti Check
Prognosti Check
IPGDx LLC
 

More from IPGDx LLC (15)

Adenocarcinoma Prognosis
Adenocarcinoma PrognosisAdenocarcinoma Prognosis
Adenocarcinoma Prognosis
 
Mesothelioma Prognosis
Mesothelioma PrognosisMesothelioma Prognosis
Mesothelioma Prognosis
 
Breast Cancer Prognosis
Breast Cancer Prognosis Breast Cancer Prognosis
Breast Cancer Prognosis
 
IPGDx EFresh
IPGDx EFreshIPGDx EFresh
IPGDx EFresh
 
Prognosti Check Phase Angle Bibliography
Prognosti Check Phase Angle BibliographyPrognosti Check Phase Angle Bibliography
Prognosti Check Phase Angle Bibliography
 
Lung Cancer prognosis
Lung Cancer prognosisLung Cancer prognosis
Lung Cancer prognosis
 
Food Safety
Food SafetyFood Safety
Food Safety
 
PrognostiCheck® Value Proposition Strategy and Focus.
PrognostiCheck® Value Proposition Strategy and Focus.PrognostiCheck® Value Proposition Strategy and Focus.
PrognostiCheck® Value Proposition Strategy and Focus.
 
PrognostiCheck® device measures prognosis. Reliable, Objective and Noninvasive.
PrognostiCheck® device measures prognosis. Reliable, Objective and Noninvasive.PrognostiCheck® device measures prognosis. Reliable, Objective and Noninvasive.
PrognostiCheck® device measures prognosis. Reliable, Objective and Noninvasive.
 
EFresh(R) device measures food freshness, juiciness and food quality.
EFresh(R) device measures food freshness, juiciness and food quality.EFresh(R) device measures food freshness, juiciness and food quality.
EFresh(R) device measures food freshness, juiciness and food quality.
 
E Fresh Beef Tenderness
E Fresh Beef TendernessE Fresh Beef Tenderness
E Fresh Beef Tenderness
 
PrognostiCheck ® - The Biological Compass
PrognostiCheck ® - The Biological CompassPrognostiCheck ® - The Biological Compass
PrognostiCheck ® - The Biological Compass
 
Efresh
EfreshEfresh
Efresh
 
Tim Thesis
Tim ThesisTim Thesis
Tim Thesis
 
Prognosti Check
Prognosti CheckPrognosti Check
Prognosti Check
 

Recently uploaded

Delhi @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girls Se...
Delhi @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girls Se...Delhi @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girls Se...
Delhi @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girls Se...
ishaguptaji14
 
Surat @Girls @ℂall 👄 XX000000XX 👄 With Cash Payment Home Delivery
Surat @Girls @ℂall 👄 XX000000XX 👄 With Cash Payment Home DeliverySurat @Girls @ℂall 👄 XX000000XX 👄 With Cash Payment Home Delivery
Surat @Girls @ℂall 👄 XX000000XX 👄 With Cash Payment Home Delivery
khandiya#G05
 
Yoga talk & yoga slides by Flametree Yoga 11 July 2024.pdf
Yoga talk & yoga slides by Flametree Yoga 11 July 2024.pdfYoga talk & yoga slides by Flametree Yoga 11 July 2024.pdf
Yoga talk & yoga slides by Flametree Yoga 11 July 2024.pdf
Stuart McGill
 
Ghaziabad @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girl...
Ghaziabad @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girl...Ghaziabad @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girl...
Ghaziabad @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girl...
ishaguptaji14
 
anthelmintic-drugs.pptx pharmacology dep
anthelmintic-drugs.pptx pharmacology depanthelmintic-drugs.pptx pharmacology dep
anthelmintic-drugs.pptx pharmacology dep
sapnasirswal
 
General Endocrinology and mechanism of action of hormones
General Endocrinology and mechanism of action of hormonesGeneral Endocrinology and mechanism of action of hormones
General Endocrinology and mechanism of action of hormones
MedicoseAcademics
 
Kayakalp Clinic Best Sexologist of patna
Kayakalp Clinic Best Sexologist of patnaKayakalp Clinic Best Sexologist of patna
Kayakalp Clinic Best Sexologist of patna
Kayakalp Clinic - Best Sexologist In Patna
 
Pernacious Anamia. payhophysiology..pptx
Pernacious Anamia. payhophysiology..pptxPernacious Anamia. payhophysiology..pptx
Pernacious Anamia. payhophysiology..pptx
Dr. vaishali Kadam
 
High Girls Call Ranchi 000XX00000 Provide Best And Top Girl Service And No1 i...
High Girls Call Ranchi 000XX00000 Provide Best And Top Girl Service And No1 i...High Girls Call Ranchi 000XX00000 Provide Best And Top Girl Service And No1 i...
High Girls Call Ranchi 000XX00000 Provide Best And Top Girl Service And No1 i...
hf66550
 
Prakinsons disease and its affect on eye.
Prakinsons disease and its affect on eye.Prakinsons disease and its affect on eye.
Prakinsons disease and its affect on eye.
Riya Bist
 
Post infectious bronchiolitis obliterans
Post infectious bronchiolitis obliteransPost infectious bronchiolitis obliterans
Post infectious bronchiolitis obliterans
drfardosy
 
Hypothyroidism / Underactive thyroid gland presentation
Hypothyroidism / Underactive thyroid gland presentationHypothyroidism / Underactive thyroid gland presentation
Hypothyroidism / Underactive thyroid gland presentation
riyaramesh2003
 
Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024
Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024
Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024
Anindya Das Adhikary
 
2024 07 12 Do you share my autistic traits_ - Google Sheets.pdf
2024 07 12 Do you share my autistic traits_ - Google Sheets.pdf2024 07 12 Do you share my autistic traits_ - Google Sheets.pdf
2024 07 12 Do you share my autistic traits_ - Google Sheets.pdf
CarriePoppy
 
PICTURE TEST IN OBSTETRICS AND GYNAECOLOGY-Aloy Okechukwu Ugwu.pptx
PICTURE TEST IN OBSTETRICS AND GYNAECOLOGY-Aloy Okechukwu Ugwu.pptxPICTURE TEST IN OBSTETRICS AND GYNAECOLOGY-Aloy Okechukwu Ugwu.pptx
PICTURE TEST IN OBSTETRICS AND GYNAECOLOGY-Aloy Okechukwu Ugwu.pptx
Aloy Okechukwu Ugwu
 
MEDICAL PROFESSIONALISM Class of compassionate care
MEDICAL PROFESSIONALISM Class of compassionate careMEDICAL PROFESSIONALISM Class of compassionate care
MEDICAL PROFESSIONALISM Class of compassionate care
Debre Berhan University
 
Introduction to Dental Implant for undergraduate student
Introduction to Dental Implant for undergraduate studentIntroduction to Dental Implant for undergraduate student
Introduction to Dental Implant for undergraduate student
Shamsuddin Mahmud
 
OBSTETRICS SEPSIS - BUNDLE APPROACH.pptx
OBSTETRICS SEPSIS - BUNDLE APPROACH.pptxOBSTETRICS SEPSIS - BUNDLE APPROACH.pptx
OBSTETRICS SEPSIS - BUNDLE APPROACH.pptx
Niranjan Chavan
 
pharmaceutical care plan scope application.pptx
pharmaceutical care plan scope application.pptxpharmaceutical care plan scope application.pptx
pharmaceutical care plan scope application.pptx
Wajid Ali
 
Heart Valves and Heart Sounds -Congenital & valvular heart disease.pdf
Heart Valves and Heart Sounds -Congenital & valvular heart disease.pdfHeart Valves and Heart Sounds -Congenital & valvular heart disease.pdf
Heart Valves and Heart Sounds -Congenital & valvular heart disease.pdf
MedicoseAcademics
 

Recently uploaded (20)

Delhi @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girls Se...
Delhi @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girls Se...Delhi @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girls Se...
Delhi @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girls Se...
 
Surat @Girls @ℂall 👄 XX000000XX 👄 With Cash Payment Home Delivery
Surat @Girls @ℂall 👄 XX000000XX 👄 With Cash Payment Home DeliverySurat @Girls @ℂall 👄 XX000000XX 👄 With Cash Payment Home Delivery
Surat @Girls @ℂall 👄 XX000000XX 👄 With Cash Payment Home Delivery
 
Yoga talk & yoga slides by Flametree Yoga 11 July 2024.pdf
Yoga talk & yoga slides by Flametree Yoga 11 July 2024.pdfYoga talk & yoga slides by Flametree Yoga 11 July 2024.pdf
Yoga talk & yoga slides by Flametree Yoga 11 July 2024.pdf
 
Ghaziabad @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girl...
Ghaziabad @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girl...Ghaziabad @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girl...
Ghaziabad @Girls @Call WhatsApp Numbers 🫦0000XX0000🫦 List For Friendship Girl...
 
anthelmintic-drugs.pptx pharmacology dep
anthelmintic-drugs.pptx pharmacology depanthelmintic-drugs.pptx pharmacology dep
anthelmintic-drugs.pptx pharmacology dep
 
General Endocrinology and mechanism of action of hormones
General Endocrinology and mechanism of action of hormonesGeneral Endocrinology and mechanism of action of hormones
General Endocrinology and mechanism of action of hormones
 
Kayakalp Clinic Best Sexologist of patna
Kayakalp Clinic Best Sexologist of patnaKayakalp Clinic Best Sexologist of patna
Kayakalp Clinic Best Sexologist of patna
 
Pernacious Anamia. payhophysiology..pptx
Pernacious Anamia. payhophysiology..pptxPernacious Anamia. payhophysiology..pptx
Pernacious Anamia. payhophysiology..pptx
 
High Girls Call Ranchi 000XX00000 Provide Best And Top Girl Service And No1 i...
High Girls Call Ranchi 000XX00000 Provide Best And Top Girl Service And No1 i...High Girls Call Ranchi 000XX00000 Provide Best And Top Girl Service And No1 i...
High Girls Call Ranchi 000XX00000 Provide Best And Top Girl Service And No1 i...
 
Prakinsons disease and its affect on eye.
Prakinsons disease and its affect on eye.Prakinsons disease and its affect on eye.
Prakinsons disease and its affect on eye.
 
Post infectious bronchiolitis obliterans
Post infectious bronchiolitis obliteransPost infectious bronchiolitis obliterans
Post infectious bronchiolitis obliterans
 
Hypothyroidism / Underactive thyroid gland presentation
Hypothyroidism / Underactive thyroid gland presentationHypothyroidism / Underactive thyroid gland presentation
Hypothyroidism / Underactive thyroid gland presentation
 
Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024
Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024
Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024
 
2024 07 12 Do you share my autistic traits_ - Google Sheets.pdf
2024 07 12 Do you share my autistic traits_ - Google Sheets.pdf2024 07 12 Do you share my autistic traits_ - Google Sheets.pdf
2024 07 12 Do you share my autistic traits_ - Google Sheets.pdf
 
PICTURE TEST IN OBSTETRICS AND GYNAECOLOGY-Aloy Okechukwu Ugwu.pptx
PICTURE TEST IN OBSTETRICS AND GYNAECOLOGY-Aloy Okechukwu Ugwu.pptxPICTURE TEST IN OBSTETRICS AND GYNAECOLOGY-Aloy Okechukwu Ugwu.pptx
PICTURE TEST IN OBSTETRICS AND GYNAECOLOGY-Aloy Okechukwu Ugwu.pptx
 
MEDICAL PROFESSIONALISM Class of compassionate care
MEDICAL PROFESSIONALISM Class of compassionate careMEDICAL PROFESSIONALISM Class of compassionate care
MEDICAL PROFESSIONALISM Class of compassionate care
 
Introduction to Dental Implant for undergraduate student
Introduction to Dental Implant for undergraduate studentIntroduction to Dental Implant for undergraduate student
Introduction to Dental Implant for undergraduate student
 
OBSTETRICS SEPSIS - BUNDLE APPROACH.pptx
OBSTETRICS SEPSIS - BUNDLE APPROACH.pptxOBSTETRICS SEPSIS - BUNDLE APPROACH.pptx
OBSTETRICS SEPSIS - BUNDLE APPROACH.pptx
 
pharmaceutical care plan scope application.pptx
pharmaceutical care plan scope application.pptxpharmaceutical care plan scope application.pptx
pharmaceutical care plan scope application.pptx
 
Heart Valves and Heart Sounds -Congenital & valvular heart disease.pdf
Heart Valves and Heart Sounds -Congenital & valvular heart disease.pdfHeart Valves and Heart Sounds -Congenital & valvular heart disease.pdf
Heart Valves and Heart Sounds -Congenital & valvular heart disease.pdf
 

Systemic Inflammatory Response Syndrome (SIRS) Prognosis

  • 1. Systemic Inflammatory Response Syndrome (SIRS) Prognosis www.ipgdx.com
  • 2. Systemic Inflammatory Response Syndrome (SIRS) is an inflammatory state affecting the whole body, frequently in response to infection. www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS
  • 3. SIRS is nonspecific and not always related to infection. It is related to Sepsis ,a condition in which individuals both meet criteria for SIRS and have a known or highly suspected infection. www.ipgdx.com INFECTION SIRS SEPSIS Phase Angle a Prognostic Factor for Survival in SIRS
  • 4. SIRS is defined as 2 or more of the following variables: Fever of more than 38°C or less than 36°C Heart rate of more than 90 beats per minute Respiratory rate of more than 20 breaths per minute or a PaCO2 level of less than 32 mm Hg Abnormal white blood cell count (>12,000/µL or <4,000/µL or >10% bands) www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS
  • 5. SIRS is one of several conditions related to systemic inflammation, organ dysfunction, and organ failure. www.ipgdx.com SIRS Pancreatitis Trauma Burns Bacteraemia Irradiation ?? Infection Phase Angle a Prognostic Factor for Survival in SIRS
  • 6. Leucocytes Endothelial cells Complement Plasmatic hemocoagulation system Platelets www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS
  • 7. The causes of SIRS are broadly classified as infectious or noninfectious. www.ipgdx.com Causes: When SIRS is due to an infection, it is considered sepsis. Noninfectious causes of SIRS include trauma, burns, pancreatitis, ischemia and haemorrhage. Phase Angle a Prognostic Factor for Survival in SIRS
  • 8. Septic shock is severe sepsis with hypo tension (systolic BP < 90mmHg) despite adequate fluid resuscitation or the requirement for vasopressors/inotropes to maintain blood pressure. www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS
  • 9. Here is an excerpt of the clinical observation study from 23rd International Symposium on Intensive Care and Emergency Medicine. www.ipgdx.com It was concluded from the study that phase Angle acts as a predictor for survival in patients with SIRS . Phase Angle a Prognostic Factor for Survival in SIRS
  • 10. PrognostiCheck ® for prognosis based upon a noninvasive diagnostic test measures the resistance,reactance and phase angle (in degrees).A low phase angle has been associated with an altered cellular membrane function. www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS
  • 11. www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS Tests were conducted on 30 consecutive patients( 11 female, 19 male ,median age of 67 [ 16.5 ] years ) after admitting them to the intensive care unit ,all of whom met 2 or more SIRS Criteria.
  • 12. In Septic shock patients,a phase angle of less than 4 degree has been reported to be associated with increases mortality. www.ipgdx.com Severity of the illness was characterized according to APACHE II(Acute Physiology and Chronis Health Evaluation) Phase Angle a Prognostic Factor for Survival in SIRS
  • 13. Non-invasive impedance analysis was performed using a tetra-polar hand-to-foot measuring device and derived phase angle was calculated as arc tan (reactance/resistance). www.ipgdx.com increasing Reactance ( )‏ Phase Angle a Prognostic Factor for Survival in SIRS
  • 14. All measurements were performed in the supine position of the patient with special care. www.ipgdx.com After 28 days, out of the 30 patients investigated, 10 had died and 20 survived. In seven out of 20 survivors,a phase angle of more than 4 degree was measured on the first day study,whereas in all patients who died,the phase angle was less than 4 degree (P=0.038) Phase Angle a Prognostic Factor for Survival in SIRS
  • 15. The conclusion was that an initial phase angle of more than 4 degree may be correlated with survival,in patients suffering with SIRS. www.ipgdx.com Phase Angle a Prognostic Factor for Survival in SIRS
  • 16. www.ipgdx.com [email_address] By IPGDx, LLC [email_address] For more information or inquiries regarding direct investments, collaborative product development and partnerships please contact below. PrognostiCheck R