Stress is the body's non-specific response to any demand placed upon it. There are several models that describe stress, including stimulus-based models that view stress as arising from life events or stressors, response-based models like the general adaptation syndrome that describe the body's physiological response to stress over time, and transactional models that emphasize cognitive appraisal of stressors and individual differences in coping. Nurses can help patients manage stress through assessment, teaching stress management techniques like relaxation, and supporting healthy coping behaviors.