This study evaluated the effect of intensification on water quality in the Ethiopian Highlands by comparing a more intensified area (Robit) to a less intensified area (Dangila). Nitrate and phosphorus levels in groundwater and streams were higher in the more intensified Robit area, especially during rainy seasons and fertilizer application periods. Pesticide levels also exceeded standards. The study recommends promoting intensification in suitable areas with watershed management and guidelines on agrochemical use to protect water quality and ecosystem health.