• Shock isa life-threatening condition which occurs
when the circulatory system fails to deliver oxygen
and nutrients to the body tissues and becomes
unable to remove waste products from the body.
• It is a descriptive term based on the symptoms
and signs secondary to one or more of a wide
range of problems.
• If not recognized and corrected as early as
possible, shock may rapidly progress to an
irreversible state with subsequent multi-organ
failure and death.
3.
DEFINITION
• Shock isdefined as a pathological state
causing inadequate oxygen delivery to the
peripheral tissues and resulting in lactic
acidosis, cellular hypoxia and disruption of
normal metabolic condition.
4.
CLASSIFICATION
Shock is generallyclassified into three major categories:
1. Hypovolemic shock
2. Cardiogenic shock
3. Distributive shock
Distributive shock is further subdivided into three
subgroups:
• a. Septic shock
• b. Neurogenic shock
• c. Anaphylactic shock
5.
Hypovolemic shock
Hypovolemic shockis present when marked reduction in
oxygen delivery
• results from diminished cardiac output secondary to
inadequate vascular volume.
• In general, it results from loss of fluid from circulation,
either directly or indirectly. e.g. Hemorrhage
• Loss of plasma due to burns
• Loss of water and electrolytes in diarrhea
• Third space loss (Internal fluid shift into inflammatory
exudates in the peritoneum, such as in pancreatitis.)
6.
Cardiogenic shock
• Cardiogenicshock is present when there is
severe reduction in oxygen delivery
secondary to impaired cardiac function.
• Usually it is due to myocardial infarction or
pericardial tamponade.
• (Cardiac tamponade is a life-threatening
medical emergency where fluid rapidly
accumulates in the sac surrounding the heart
(pericardium).
7.
Septic Shock
• SepticShock (vasogenic shock) develops as a
result of the systemic effect of infection.
• It is the result of a septicemia with endotoxin
and exotoxin release by gram-negative and
gram-positive bacteria.
• Despite normal or increased cardiac output and
oxygen delivery, cellular oxygen consumption is
less than normal due to impaired extraction as
a result of impaired metabolism.
8.
Neurogenic shock
• Neurogenicshock results primarily from the
disruption of the sympathetic nervous system
which may be due to pain or loss of
sympathetic tone, as in spinal cord injuries.
9.
PATHO PHYSIOLOGY OFSHOCK
• Shock stimulates a physiologic response.
• This circulatory response to hypotension is to
conserve perfusion to the vital organs (heart and
brain) at the expense of other tissues.
• Progressive vasoconstriction of skin, splanchnic and
renal vessels leads to renal corticalnecrosis and acute
renal failure.
• If not corrected in time, shock leads to organ failure
and sets up a vicious circle with hypoxia and acidosis.
10.
CLINICAL FEATURES
The clinicalpresentation varies according to the cause.
But in general patients with hypotension and reduced
tissue perfusion presents with:
1. Tachycardia
2. Feeble pulse
3. Narrow pulse pressure
4. Cold extremities (except septic shock)
5. Sweating, anxiety
6. Breathlessness / Hyperventilation
7. Confusion leading to unconscious state
11.
Clinical features ofhypovolemic shock in adults with
estimated volume loss.
• Estimated blood loss 750-1500ml 1500ml-2000ml >2000
ml
• Blood pressure Normal Reduced Severely Reduced Pulse
rate >100/min >120/m >140/m very feeble
• Capillary refill Slow Slow Undetectable .
• Respiratory rate 20-30/m 30-40/m >35/m
• Urinary flow rate (Normal: 30-60 ml/hr or 0.5-
1ml/kg/hr)
• 20-30/hr 10-20/hr 0-10/hr
• Mental state(CNS) Anxious confused Lethargic, comatose
12.
MANAGEMENT OF SHOCK
•Treatment is aimed at restoring oxygen
delivery to the cells of vital organs as rapidly
as possible.
• The management depends on the cause and
type of shock.
13.
MANAGEMENT OF SHOCK
GeneralManagement
• Monitor the airway, breathing and circulation as first
priority
• Stop bleeding
• Fluid resuscitation, preferably crystalloids
• Head down position
• Treat the cause
• Transfusion of compatible blood if indicated
• Oxygen and other supportive measures like inotropic agents
• Monitoring of resuscitation effectiveness: e.g. determine
hourly urine output, blood pressure and pulse rate
14.
MANAGEMENT OF SHOCK
SpecificManagement
Hypovolemic Shock: The goal of treatment is to
restore vascular volume. This is effected by:
• General approach as above
• Fluid and blood replacement
• Oxygen support etc.
15.
Management Septic Shock
•Initial management as above
• Appropriate antibiotics especially for gram-
negative microorganisms Inotropic support
such as adrenaline and dopamine
• Surgical eradication of the infection focus
16.
Cardiogenic shock
• Initialmanagement as above
• Inotropes (Inotropes are medications that
alter the force or energy of your heart’s
muscular contractions.)
• Treat the causes
17.
Neurogenic shock
• Initialmanagement as above
• Pain relief
• Treat the causes, give supportive measures
like inotropic support
18.
COMPLICATIONS OF SHOCK
Themain complications of severe shock include:
1. Shock lung (ARDS)
2. Acute renal failure
3. Gastrointestinal ulceration
4. Disseminated intravascular clotting
5. Multiorgan failure
6. Death
• Therefore, a patient in shock requires immediate
emergency treatment.
• Early diagnosis and immediate correction of shock
prevents permanent organ damage and death.
• Homeopathic therapeuticsfor shock focus on
addressing the immediate emotional or
physical trauma using highly diluted remedies.
• The remedy selected depends entirely on the
root cause and the specific physical or
psychological symptoms the patient exhibits.
21.
• Aconitum napellus:The primary remedy for sudden fright,
panic, or intense fear following a traumatic experience. [
• Arnica montana: Indicated for physical trauma, bruising,
and shock where the person feels battered and insists they
are "fine" and refuse assistance.
• Ignatia amara: Often utilized for emotional shock, grief, or
mood swings following sudden bad news or loss.
• Hypericum perforatum: Known as the "Arnica of the
nerves," this is used when shock is accompanied by
shooting pains, tingling, or occurs after injuries to nerve-
rich areas like the spine or fingertips.
• Carbo vegetabilis: Indicated for states of deep collapse or
fainting where the person feels cold, struggles to breathe,
and wants to be fanned.