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Role Of Zinc And Manganese in
Health
Dr. Shweta Malik (Assistant Professor)
Shwtmalik1@gmail.com
Home-Science Department
Swami Vivekanand Subharti University, Meerut
Introduction
• Zinc is a trace element that is necessary for a healthy
immune system. A lack of zinc can make a person more
susceptible to disease and illness.
• It is responsible for a number of functions in the
human body, and it helps stimulate the activity of at
least 100 different enzymes. Only a small intake of zinc
is necessary to reap the benefits.
• Currently, the recommended dietary allowance (RDA)
for zinc in the United States is 8 milligrams (mg) a day
for women and 11 mg a day for men.
• The element is naturally found in many different foods,
but it is also available as a dietary supplement.
• Zinc is vital for a healthy immune system,
correctly synthesizing DNA, promoting healthy
growth during childhood, and healing wounds.
Role In Health
1) Zinc and regulating immune
function
• Define by A research in European Journal of
Immunology, the human body needs zinc to
activate T lymphocytes (T cells).
T cells help the body in two ways:
1.Controlling and regulating immune responses.
2. Attacking infected or cancerous cells.
• Zinc deficiency can severely impair immune
system function.
2) Zinc for treating diarrhea
• According to the World Health Organization,
diarrhea kills an astonishing 1.6 million
children under 5 every year. Zinc pills may help
reduce diarrhoea.
• Acc. to plosmedicine journal study which
“followed a nationwide public health
campaign to increase zinc use for childhood
diarrhoea in Bangladesh,” confirmed that a
10-day course of zinc tablets is effective at
treating diarrhoea and also helps prevent
future bouts of the condition.
3) Zinc effects on learning and
memory
Zinc play a crucial role in regulating how
neurons communicate with one another,
affecting how memories are formed and how
we learn.
-It improve the memory power.
4) Zinc’s role in wound healing
• Zinc plays a role in maintaining skin integrity and
structure. Patients experiencing chronic wounds or
ulcers often have deficient zinc metabolism and lower
serum zinc levels. Zinc is often used in skin creams for
treating diaper rash or other skin irritations.
• A Swedish study that analysed zinc in wound healing
concluded, “topical zinc may stimulate leg ulcer healing
by enhancing re-epithelialization, decreasing
inflammation and bacterial growth. When zinc is
applied on wounds, it not only corrects a local zinc
deficit but also acts pharmacologically.”
5) Zinc for preventing Age-related
Macular degeneration (AMD)
• Zinc prevents cellular damage in the retina,
which helps in delaying the progression of
AMD and vision loss, according to a study
published in the Archives of Ophthalmology.
9) Role in fertility
• Several studies and trials have linked poor zinc
status with low sperm quality. For example,
one study in the Netherlands found that
subjects had a higher sperm count after zinc
sulfate and folic acid supplementation. In
another study, researchers concluded that
poor zinc intake may be a risk factor for low
quality of sperm and male infertility.
Role in Pregnancy
• Zinc plays an important role in many biological
functions including protein synthesis, cellular
division and nucleic acid metabolism.
• Many studies shows that 82% of the pregnant
women worldwide have inadequate zinc intakes.
• The effect of zinc supplementation on preterm
birth, if causal, might reflect a reduction in
maternal infection, a primary cause of
prematurity.
• Poor maternal zinc status has been associated
with foetal loss, congenital malformations
(जन्मजात विकृ ततयाां), intrauterine growth retardation
(अांतर्गर्ागशयी विकास मांदता), reduced birth weight.
What are the benefits and effects of
manganese
• Manganese is a trace mineral. It is vital for the
human body, but people only need it in small
amounts.
• Manganese contributes to many bodily
functions, including the metabolism of amino
acids, cholesterol, glucose, and carbohydrates.
It also plays a role in bone formation, blood
clotting, and reducing inflammation
• The human body cannot produce manganese,
but it can store it in the liver, pancreas, bones,
kidneys, and brain. A person usually obtains
manganese from their diet.
• Health benefits
• The potential health benefits of manganese
include:
• Small amounts of manganese are present in
raw pineapple, pinto beans, and pecans.
1.Providing antioxidants
• Manganese helps form an antioxidant enzyme called superoxide
dismutase (SOD). Antioxidants shield the body from free radicals,
which are molecules that destroy or damage cells in the body.
• The authors of a 2011 study found that SOD helps break down one
of the more dangerous free radicals, called superoxide, into smaller
components that are not harmful.
• In laboratory and animal models, this process could reduce
inflammation related to lung pleurisy(thin layers of tissue that
separate to lungs from your chest wall), inflammatory bowel
disease swelling in digestive tract, and psoriasis. skin diseases
2.Supporting bone health
• Manganese may help promote strong, dense
bones when combined with other nutrients,
such as calcium and vitamin D.
• Although some earlier studies have suggested
that manganese could make bones denser,
more recent research has noted that calcium
and vitamin D are the most significant
promoters of good bone health.
3.Reducing blood sugar
• For people with diabetes, manganese may help lower blood
sugar levels.
• The authors of a 2014 study that took place in South Korea
found that people with diabetes had lower levels of
manganese in their bodies. What is not clear, however, is
whether this is a causal factor or a result of diabetes.
• Another study, this time in mice, indicated that manganese
helps the pancreas create insulin. Insulin is what the body
uses to help regulate blood sugar.
• Taking manganese supplements may help a person with
diabetes produce more insulin naturally, but more research
in humans is necessary to confirm these effects.
4.Healing wounds
• Along with vitamin K, manganese aids the
formation of blood clots. Blood clotting, which
keeps the blood in a damaged blood vessel, is
the first stage of wound healing.
• So, having adequate levels of manganese in
the body may help stop blood loss when a
person has an open wound.

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Role of zinc in health

  • 1. Role Of Zinc And Manganese in Health Dr. Shweta Malik (Assistant Professor) Shwtmalik1@gmail.com Home-Science Department Swami Vivekanand Subharti University, Meerut
  • 2. Introduction • Zinc is a trace element that is necessary for a healthy immune system. A lack of zinc can make a person more susceptible to disease and illness. • It is responsible for a number of functions in the human body, and it helps stimulate the activity of at least 100 different enzymes. Only a small intake of zinc is necessary to reap the benefits. • Currently, the recommended dietary allowance (RDA) for zinc in the United States is 8 milligrams (mg) a day for women and 11 mg a day for men. • The element is naturally found in many different foods, but it is also available as a dietary supplement.
  • 3. • Zinc is vital for a healthy immune system, correctly synthesizing DNA, promoting healthy growth during childhood, and healing wounds. Role In Health
  • 4. 1) Zinc and regulating immune function • Define by A research in European Journal of Immunology, the human body needs zinc to activate T lymphocytes (T cells). T cells help the body in two ways: 1.Controlling and regulating immune responses. 2. Attacking infected or cancerous cells. • Zinc deficiency can severely impair immune system function.
  • 5. 2) Zinc for treating diarrhea • According to the World Health Organization, diarrhea kills an astonishing 1.6 million children under 5 every year. Zinc pills may help reduce diarrhoea. • Acc. to plosmedicine journal study which “followed a nationwide public health campaign to increase zinc use for childhood diarrhoea in Bangladesh,” confirmed that a 10-day course of zinc tablets is effective at treating diarrhoea and also helps prevent future bouts of the condition.
  • 6. 3) Zinc effects on learning and memory Zinc play a crucial role in regulating how neurons communicate with one another, affecting how memories are formed and how we learn. -It improve the memory power.
  • 7. 4) Zinc’s role in wound healing • Zinc plays a role in maintaining skin integrity and structure. Patients experiencing chronic wounds or ulcers often have deficient zinc metabolism and lower serum zinc levels. Zinc is often used in skin creams for treating diaper rash or other skin irritations. • A Swedish study that analysed zinc in wound healing concluded, “topical zinc may stimulate leg ulcer healing by enhancing re-epithelialization, decreasing inflammation and bacterial growth. When zinc is applied on wounds, it not only corrects a local zinc deficit but also acts pharmacologically.”
  • 8. 5) Zinc for preventing Age-related Macular degeneration (AMD) • Zinc prevents cellular damage in the retina, which helps in delaying the progression of AMD and vision loss, according to a study published in the Archives of Ophthalmology.
  • 9. 9) Role in fertility • Several studies and trials have linked poor zinc status with low sperm quality. For example, one study in the Netherlands found that subjects had a higher sperm count after zinc sulfate and folic acid supplementation. In another study, researchers concluded that poor zinc intake may be a risk factor for low quality of sperm and male infertility.
  • 10. Role in Pregnancy • Zinc plays an important role in many biological functions including protein synthesis, cellular division and nucleic acid metabolism. • Many studies shows that 82% of the pregnant women worldwide have inadequate zinc intakes. • The effect of zinc supplementation on preterm birth, if causal, might reflect a reduction in maternal infection, a primary cause of prematurity.
  • 11. • Poor maternal zinc status has been associated with foetal loss, congenital malformations (जन्मजात विकृ ततयाां), intrauterine growth retardation (अांतर्गर्ागशयी विकास मांदता), reduced birth weight.
  • 12. What are the benefits and effects of manganese • Manganese is a trace mineral. It is vital for the human body, but people only need it in small amounts. • Manganese contributes to many bodily functions, including the metabolism of amino acids, cholesterol, glucose, and carbohydrates. It also plays a role in bone formation, blood clotting, and reducing inflammation
  • 13. • The human body cannot produce manganese, but it can store it in the liver, pancreas, bones, kidneys, and brain. A person usually obtains manganese from their diet. • Health benefits • The potential health benefits of manganese include: • Small amounts of manganese are present in raw pineapple, pinto beans, and pecans.
  • 14. 1.Providing antioxidants • Manganese helps form an antioxidant enzyme called superoxide dismutase (SOD). Antioxidants shield the body from free radicals, which are molecules that destroy or damage cells in the body. • The authors of a 2011 study found that SOD helps break down one of the more dangerous free radicals, called superoxide, into smaller components that are not harmful. • In laboratory and animal models, this process could reduce inflammation related to lung pleurisy(thin layers of tissue that separate to lungs from your chest wall), inflammatory bowel disease swelling in digestive tract, and psoriasis. skin diseases
  • 15. 2.Supporting bone health • Manganese may help promote strong, dense bones when combined with other nutrients, such as calcium and vitamin D. • Although some earlier studies have suggested that manganese could make bones denser, more recent research has noted that calcium and vitamin D are the most significant promoters of good bone health.
  • 16. 3.Reducing blood sugar • For people with diabetes, manganese may help lower blood sugar levels. • The authors of a 2014 study that took place in South Korea found that people with diabetes had lower levels of manganese in their bodies. What is not clear, however, is whether this is a causal factor or a result of diabetes. • Another study, this time in mice, indicated that manganese helps the pancreas create insulin. Insulin is what the body uses to help regulate blood sugar. • Taking manganese supplements may help a person with diabetes produce more insulin naturally, but more research in humans is necessary to confirm these effects.
  • 17. 4.Healing wounds • Along with vitamin K, manganese aids the formation of blood clots. Blood clotting, which keeps the blood in a damaged blood vessel, is the first stage of wound healing. • So, having adequate levels of manganese in the body may help stop blood loss when a person has an open wound.