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DECODING
MENTAL
HEALTH
Digital Precision
Medicine for
Mental Health
1 out of 4 of us
will experience a
mental disorder1
Mental illness will be
the leading cause of
disability by 20301
costing $6 Trillion
Sources: 1WHO Global burden of disease, 2ncbi.nlm.nih.gov/pmc/articles/PMC4392551
>45% of patients with
chronic conditions struggle
with behavioral health2
THERMOMETER STETHOSCOPE BLOOD PRESSURE
MONITOR
GLUCOSE
METER
MENTAL
HEALTH
?
EVERY OTHER MEDICAL PRACTICE USES
OBJECTIVE MEASUREMENT TOOLS
No objective
monitoring
for mental health
PROBLEM
TECHNOLOGY
Feel’s proprietary
Digital Precision
Medicine Platform
brings continuous
and passive
monitoring to
mental health.
MOOD
MENTAL STRESS SLEEP
PHYSICAL
SYMPTOMS
SOCIAL ACTIVITY
PSYCHOMOTOR
ACTIVITY
COGNITIVE FUNCTIONING
PSYCHOPHYSIOLOGICAL
MONITORING
Digital Biomarkers
Proprietary Algorithms
Continuous Monitoring
Wearable
Devices
Sensors of the
Mobile Phone
Voice, Video &
Text
VITALS
PHYSICAL ACTIVITY BODY ENERGY
1. REMOTE MONITORING
DEVICE & APP
2. PROPRIETARY
ALGORITHMS
3. REAL-TIME SUPPORT
& ADHERENCE
TOOLS
5. DIGITAL CBT
PROGRAM &
PSYCHO-
EDUCATION
4. CLINICIAN’S
DASHBOARD &
COACHING
Sleep
Physical &
psychomotor activity
Stress
Emotions
Social activity
SOLUTION | LINKING REMOTE MONITORING WITH PRECISE INTERVENTION 24/7/365
6. MEDICATION
IMPACT TO PATIENTS ACROSS MENTAL HEALTH CONDITIONS
MDD
Countries: 5 Subjects: 817
Total countries
9
Total Patients
2,727
23 Research &
clinical
studies
Active 2018-
2024
PTSD
Countries: 1 Subjects: 95
Healthy w/ risk factors
Countries: 5 Subjects: 1154
ADHD
Countries: 1 Subjects: 100
Eating Disorders
Countries: 1 Subjects: 80
MDD
GAD
PTSD
ADHD
Eating
Disorders
Number
of
studies
Healthy
w/
risk
factors
GAD
Countries: 5 Subjects: 427
6 THERAPEUTIC
AREAS IN CNS
6
TAs PIPELINE
(e.g. Oncology,
Hematology et al.)
*Starting in 2024
MS*
Countries: 1 Subjects: 50
5
6
3
7
1 1 1
0
2
4
6
8
MS
PUBLICATIONS
Precision DTx
delivers superior
improvement in
outcomes in
depression and/or
anxiety
Read Publication
87% precision in
detecting
changes in the
mood state of
patients in
psychiatry
Read Publication
Psychophysiologi
cal index for
Stress
Emotion
Detection 2
Outcomes of Feel
DTx for
Depression and
Anxiety
Precision and
accuracy of
emotional state
detection and
recognition
Psychophysiologi
cal index for
Stress Resilience
Psychophysiologi
cal index for
Stress strongly
correlates with
changes in
Cortisol levels
Read Publication
Psychophysiologi
cal index for
Stress
Electrodermal
Activity (EDA)
can be a stress
resilience metric
in stressful
conditions
Read Publication
Psychophysiologi
cal index for
Stress strongly
correlates with
changes in the
Endocannabinoid
System
Read Publication
Precision DTx
shows
improvement in
mental health
outcomes for
ADHD
populations
Read Publication
Outcomes of Feel
DTx for ADHD
Digital Biomarker
for Detection of
ADHD
Detection of
ADHD utilizing
physiological
signals from
wearables
Publication
Pending
PATENTS
Patent for
detecting
changes in the
mood state of an
individual based
on physiological &
digital data
Patent No:
US1141068282
Method for
detecting and
recognizing an
emotional state
of a user
(Continuation)
Patent Granted
Depression
Relapse Digital
Biomarker
Emotion
Detection 2
Emotion
Detection
Emotion
Detection 2
ADHD Digital
Biomarker
Method for
characterizing,
detecting, and
monitoring ADHD
Patent pending
Insomnia Digital
Biomarker
System and
method for
characterizing,
detecting, and
monitoring
insomnia
Patent pending
System and
method for
characterizing,
detecting, and
monitoring
relapse in
depression
Patent pending
STATS
TEAM
INVESTORS
CORE TEAM
800+
TEAM MEMBER
PUBLICATIONS
16000+
TEAM MEMBER
CITATIONS
9
POST-DOCS
IN THE CORE TEAM
4
PROFESSORS OF
PSYCHIATRY
31
TEAM MEMBERS
IN THE USA & EUROPE
$180k
CORE GROSS
MONTHLY BURN RATE
A COMPANY OF:
GEORGE
ELEFTHERIOU
CO-FOUNDER & CEO
FORMER MCKINSEY,
COLUMBIA
SHARON KAPLOW
VP OF CLINICAL
OPERATIONS,
FORMER CLINICAL
LEAD AbleTo
HARIS TSIRBAS, PhD
CO-FOUNDER & CTO
PHD IN BIOMEDICAL
ENGINEERING
LEADERSHIP TEAM
INDUSTRY EXPERTS
MICHEL
VOUNATSOS
FORMER CEO OF
BIOGEN
DR. NIKOS
DASKALAKIS
PROFESSOR OF
PSYCHIATRY AT
HARVARD
STAYCE BECK
FORMER DIRECTOR
PERSONALIZED
MEDICINE &
BIOMARKERS @ FDA
PSYCHIATRY EXPERTS
DR. PETER
YELLOWLEES
PROFESSOR OF
PSYCHIATRY AT
UC DAVIS
DR. JOAQUIN
ANGUERA
PROFESSOR OF
PSYCHIATRY AT
UCSF
TORSTEN
OLETZKY
FORMER CEO OF
ERGO
EXISTING ROUND
MILESTONES
FDA approval of our wearable as a 510k class II medical device
Launch as a Drug+ in the market & clearance of Feel DTx
program as an adjunct to medication
PRE-SERIES A
FUNDRAISING
$1M left in a
$3.5M round to
reach an
inflection point Empatica closed their series B financing from Sanofi after receiving
FDA clearance for a similar device
Recent FDA clearance of DTx for the Adjunctive Treatment of MDD
Terms: Convertible Note with $30M Cap and 20% Discount
Closed $2.5M led by expert Neurotech investors (Satori Neuro)
George Eleftheriou, Co-Founder & CEO
479 Jessie Street, San Fransisco, CA 94103
+1 551 232 1020 | george@feeltherapeutics.com | www.feeltherapeutics.com

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PDT 99 - $3.5M - Seed - Feel Therapeutics.pdf

  • 2. 1 out of 4 of us will experience a mental disorder1 Mental illness will be the leading cause of disability by 20301 costing $6 Trillion Sources: 1WHO Global burden of disease, 2ncbi.nlm.nih.gov/pmc/articles/PMC4392551 >45% of patients with chronic conditions struggle with behavioral health2
  • 3. THERMOMETER STETHOSCOPE BLOOD PRESSURE MONITOR GLUCOSE METER MENTAL HEALTH ? EVERY OTHER MEDICAL PRACTICE USES OBJECTIVE MEASUREMENT TOOLS No objective monitoring for mental health PROBLEM
  • 4. TECHNOLOGY Feel’s proprietary Digital Precision Medicine Platform brings continuous and passive monitoring to mental health. MOOD MENTAL STRESS SLEEP PHYSICAL SYMPTOMS SOCIAL ACTIVITY PSYCHOMOTOR ACTIVITY COGNITIVE FUNCTIONING PSYCHOPHYSIOLOGICAL MONITORING Digital Biomarkers Proprietary Algorithms Continuous Monitoring Wearable Devices Sensors of the Mobile Phone Voice, Video & Text VITALS PHYSICAL ACTIVITY BODY ENERGY
  • 5. 1. REMOTE MONITORING DEVICE & APP 2. PROPRIETARY ALGORITHMS 3. REAL-TIME SUPPORT & ADHERENCE TOOLS 5. DIGITAL CBT PROGRAM & PSYCHO- EDUCATION 4. CLINICIAN’S DASHBOARD & COACHING Sleep Physical & psychomotor activity Stress Emotions Social activity SOLUTION | LINKING REMOTE MONITORING WITH PRECISE INTERVENTION 24/7/365 6. MEDICATION
  • 6. IMPACT TO PATIENTS ACROSS MENTAL HEALTH CONDITIONS MDD Countries: 5 Subjects: 817 Total countries 9 Total Patients 2,727 23 Research & clinical studies Active 2018- 2024 PTSD Countries: 1 Subjects: 95 Healthy w/ risk factors Countries: 5 Subjects: 1154 ADHD Countries: 1 Subjects: 100 Eating Disorders Countries: 1 Subjects: 80 MDD GAD PTSD ADHD Eating Disorders Number of studies Healthy w/ risk factors GAD Countries: 5 Subjects: 427 6 THERAPEUTIC AREAS IN CNS 6 TAs PIPELINE (e.g. Oncology, Hematology et al.) *Starting in 2024 MS* Countries: 1 Subjects: 50 5 6 3 7 1 1 1 0 2 4 6 8 MS
  • 7. PUBLICATIONS Precision DTx delivers superior improvement in outcomes in depression and/or anxiety Read Publication 87% precision in detecting changes in the mood state of patients in psychiatry Read Publication Psychophysiologi cal index for Stress Emotion Detection 2 Outcomes of Feel DTx for Depression and Anxiety Precision and accuracy of emotional state detection and recognition Psychophysiologi cal index for Stress Resilience Psychophysiologi cal index for Stress strongly correlates with changes in Cortisol levels Read Publication Psychophysiologi cal index for Stress Electrodermal Activity (EDA) can be a stress resilience metric in stressful conditions Read Publication Psychophysiologi cal index for Stress strongly correlates with changes in the Endocannabinoid System Read Publication Precision DTx shows improvement in mental health outcomes for ADHD populations Read Publication Outcomes of Feel DTx for ADHD Digital Biomarker for Detection of ADHD Detection of ADHD utilizing physiological signals from wearables Publication Pending
  • 8. PATENTS Patent for detecting changes in the mood state of an individual based on physiological & digital data Patent No: US1141068282 Method for detecting and recognizing an emotional state of a user (Continuation) Patent Granted Depression Relapse Digital Biomarker Emotion Detection 2 Emotion Detection Emotion Detection 2 ADHD Digital Biomarker Method for characterizing, detecting, and monitoring ADHD Patent pending Insomnia Digital Biomarker System and method for characterizing, detecting, and monitoring insomnia Patent pending System and method for characterizing, detecting, and monitoring relapse in depression Patent pending
  • 9. STATS TEAM INVESTORS CORE TEAM 800+ TEAM MEMBER PUBLICATIONS 16000+ TEAM MEMBER CITATIONS 9 POST-DOCS IN THE CORE TEAM 4 PROFESSORS OF PSYCHIATRY 31 TEAM MEMBERS IN THE USA & EUROPE $180k CORE GROSS MONTHLY BURN RATE A COMPANY OF: GEORGE ELEFTHERIOU CO-FOUNDER & CEO FORMER MCKINSEY, COLUMBIA SHARON KAPLOW VP OF CLINICAL OPERATIONS, FORMER CLINICAL LEAD AbleTo HARIS TSIRBAS, PhD CO-FOUNDER & CTO PHD IN BIOMEDICAL ENGINEERING LEADERSHIP TEAM INDUSTRY EXPERTS MICHEL VOUNATSOS FORMER CEO OF BIOGEN DR. NIKOS DASKALAKIS PROFESSOR OF PSYCHIATRY AT HARVARD STAYCE BECK FORMER DIRECTOR PERSONALIZED MEDICINE & BIOMARKERS @ FDA PSYCHIATRY EXPERTS DR. PETER YELLOWLEES PROFESSOR OF PSYCHIATRY AT UC DAVIS DR. JOAQUIN ANGUERA PROFESSOR OF PSYCHIATRY AT UCSF TORSTEN OLETZKY FORMER CEO OF ERGO
  • 10. EXISTING ROUND MILESTONES FDA approval of our wearable as a 510k class II medical device Launch as a Drug+ in the market & clearance of Feel DTx program as an adjunct to medication PRE-SERIES A FUNDRAISING $1M left in a $3.5M round to reach an inflection point Empatica closed their series B financing from Sanofi after receiving FDA clearance for a similar device Recent FDA clearance of DTx for the Adjunctive Treatment of MDD Terms: Convertible Note with $30M Cap and 20% Discount Closed $2.5M led by expert Neurotech investors (Satori Neuro)
  • 11. George Eleftheriou, Co-Founder & CEO 479 Jessie Street, San Fransisco, CA 94103 +1 551 232 1020 | george@feeltherapeutics.com | www.feeltherapeutics.com