Patellofemoral Pain Syndrome (PFPS), commonly known as runner's knee, is a condition characterized by anterior knee pain that is aggravated by activities involving the patellofemoral joint like climbing stairs, sitting with bent knees, or squatting. It is often caused by overuse injuries and biomechanical faults that cause abnormal tracking of the patella. Examination involves assessing for factors like patellar maltracking, tight muscles, and weakness. Treatment is primarily non-operative and focuses on exercises, bracing, taping, and orthotics to address biomechanical faults and strengthen the quadriceps muscles.