Healthy animals equals healthy, productive people

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Healthy animals equals
healthy, productive people
Lorne A Babiuk
University of Alberta
Livestock-based options for sus...

Global challenges
• Currently 1 billion people go to bed hungry
• By 2050 predict 2 billion more people
• Land resource...

Global Challenges (cont.)
• Livestock are a reliable cash income
• Raise production of milk, meat and fish
• 500 millio...

Gains in meat consumption in developing
countries are outpacing those of developed
FAO 2006

70% of the world’s livestock (18.5 billion head) are in developing
countries and the share is growing
FAO
Livestock in ...

Livestock keepers in developing countries
One billion people earning <$2 a day depend on livestock:
• 600 million in Sou...

Percent of production from smallholders
Smallholders still dominate production in many counties
BMGF, FAO and ILRI

Challenges
• Mortality due to infections
• Limits areas for raising livestock
• Economic coats
- animals
- humans

Economic Impact of
Animal Diseases
• Rinderpest - limited trade/exports
• BSE – UK $ 2.5 billion direct compensation
•...

Currently over 70% of New
or Emerging Diseases
are Zoonotic

Zoonosis
• Economic consequences to farms/producers
• International trade barriers
• Price of food
• Human health

Transmission from Humans to
Animals and Back

Biotechnology in the
Developed world
Biotechnology in the
Developing world

Genomic approaches to Animal
Health
• Vaccination
• Breeding disease resistant animals
• Marker assisted management
h...

VACCINES
“Vaccination is one of the most
cost-effective approaches for the
management of infectious
disease”

The problem

The solution
• Develop thermal stable vaccines
• Protection in multiple species
• Employ as vectors for other pathogens...

18
Etiology
The Capripoxvirus Group
LUMPY SKIN DISEASE
Limited Host Range No Known Wildlife Reservoir
SHEEP POX GOAT ...

Removal of virulence gene

Figure 6: Clinical signs and gross pathology following vaccination (1 x 102.3 pfu) and challenge in
sheep and goats at 10...

Stage 2: Generation of the KO_1 vectored RVF-PPR
X
Schematic showing the generation of the KO_1 vaccine construct contai...

Genetics can improve production
• Classical breeding/selection
• Biotechnology

Agriculture
• Knowledge of the genetic
variants that affect livestock
health and productivity can
assist with breeding...

Genomics in Livestock?
• Parentage or the origin of a piece of meat
• To identify carriers of a genetic disease
• To ma...

Bovine Macro-array

Determining which alleles
are present (genotyping)
• Genotyping chips can
be used to determine
which SNPs are
present...

The Opportunity
• Converting DNA sequence into useful
genotyping tools
• Analyzing thousands of animals to convert
gen...

Marker Assisted Management
Is this the best use of
our beef?

Marker Assisted Management: cont’d
High Quality
Carcass
Feedlot

Marker Assisted Management: cont’d

Conclusion
• Increasing food security is critical
• Technology is available to benefit society
• Adoption of technology...

Healthy animals equals healthy, productive people

Healthy animals equals healthy, productive people

Healthy animals equals healthy, productive people

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