Comprehensive Overview of Gastro Retentive Drug Delivery Systems and Formulation Approaches

Comprehensive Overview of Gastro Retentive Drug Delivery Systems and Formulation Approaches

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  GASTRO RETENTIVE DRUG DELIVERYSYSTEM Mr. M. BALASUNDARESAN, M.Pharm., Assistant Professor, Department of Pharmaceutics, Arunai College of Pharmacy, Tiruvannamalai
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  A. Floating System/ Low Density System a. Effervescent System 1. Volatile Liquid / Vacuum Type System i. Inflatable System ii. Intragastric Floating System iii. Intragastric Osmotically Controlled System 2. Matrix Tablet i. Single Layer Floating / Hydrodynamically Balanced System ii. Bilayer Floating 3. Gas Generating System i. Floating Pills / Multilayer Floating ii. Floating Capsules iii. Ion Exchange Resins Floating Systems b. Non-Effervescent 1. Colloidal Gel Barrier 2. Alginate Beads 3. Microballons / Hollow Microspheres 4. Microporous Compartment system 4. B. Non floating System a. High Density System b. Bioadhesive / Mucoahesive System c. Swellable Expandable, Unflodable System d. Superporous Membrane System e. Magnetic System f. Raft System Formulation Approaches for Formulation of GRDDS
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