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"COMBATING DRUG RESISTANCE THROUGH HOME
MEDICINE”`
Neha Ansari
B-pharm 2nd
year
CONTENT
Drug Resistance
Causes of Drug Resistance
Mechanism of Drug Resistance
Home medicine to combat /decrease Drug
Resistance.
DRUG RESISTANCE
 Drug Resistance occurs when
microorganisms (bacteria, viruses,
fungi or parasites) adapt and
become less susceptible to
medications, making treatments
ineffective.
 When bacteria becomes resistant
to drugs then it is known as
antibiotic resistance.
 According to WHO, 7 lakhs death
occurs annually due to antibiotic
resistant infection.
CAUSES OF DRUG RESISTANCE
Overuse and misuse of Drugs.
Poor Hygiene and Sanitation.
Lack of new antibiotic development.
Genetic Mutation and Adaptation.
Inappropriate Prescribing.
CAUSES OF DRUG RESISTANCE
Antibiotic use in food producing animals kills or susceptible
bacteria, allowing antibiotic - resistant bacteria to thrive.
Resistant bacteria are transmitted to human through the food
supply.
 These bacteria can cause infection in humans that may lead
to adverse health consequences.
MECHANISM OF DRUGS RESISTANCE
The main mechanisms by which microorganisms exhibit resistance to
drugs are :
Drug inactivation or modification i.e. enzymatic deactivation of Penicillin G in some
penicillin - resistant bacteria through the production of ß – lactamases.
Alternation of target site : e.g., alternation of PBP – the binding target site of penicillin
- in MRSA and other penicillin – resistant bacteria.
Reduced Drug Accumulation : by decreasing drug permeability and /or increasing
actice efflux ( pumping out ) of the drugs across the cell surface.
HOME MEDICINE REMEDIES TO COMBAT
DRUG RESISTANCE
Herbal remedies (e.g. Turmeric
and Ginger)
Natural antimicrobials (e.g.
honey, garlic )
Probiotics and gut health.
HERBAL REMEDIES
• Turmeric (Curcuma
longa)
- Anti Inflammatory
• Ginger ( Zingiber
officinale)
- Antimicrobial
NATURAL ANTIMICROBIALS
Honey
– Antibacterial properties.
Garlic ( Allium sativum )
– Antimicrobial .
Tea tree oil
– Antifungal.
PROBIOTICS AND GUTHEALTH
Fermented food
- Yogurt and Kefir .
THANK YOU