The document discusses using Argonne National Laboratory's GREET model to estimate the benefits of alternative fuel vehicles through life-cycle analysis. It introduces the GREET model, which evaluates energy use and emissions from vehicle/fuel systems on a well-to-wheels basis. As an example of its use, recent research on greenhouse gas emissions from shale gas is mentioned. The document outlines how the GREET model separates energy use and estimates emissions, allowing life-cycle comparisons of different vehicle and fuel options.