Gomez-Ricoy-Velez-Sepulveda Poster SfN2015 Ca TMS-TES ADJuan Gomez
This document summarizes a study investigating the use of EEG-triggered transcranial electric stimulation (TES) or transcranial magnetic stimulation (TMS) to modulate calcium signaling in Alzheimer's disease. Computer models suggest that TES/TMS can modify the amplitude and speed of calcium diffusion in neuronal columns. The study hypothesizes that TES/TMS could increase calcium amplitude and speed in columns with abnormal states to better match global EEG patterns, potentially improving function. Experimental validation is still needed to test effects on calcium homeostasis and avoid potential damage.
Gomez_Molina Restrepo-V Botero=P Field Generated by Waves Downloaded Jul 15 ...Juan Gomez
This document summarizes a study that used computer simulations to model the extracellular field (EF) generated by waves of neural activation. Specifically, it modeled:
1) Bilateral waves, where subregions could be in an activated, resting, or inhibited state. This produced biphasic, Gaussian, and Mexican hat waveforms.
2) Stochastic propagation waves, where activation spread randomly along a moving wavefront.
The simulations showed that bipolar recordings of EF are affected by the distance and movement of the wave relative to the electrodes. Distorted waves may cause pathologies, and modulating waves with electric or magnetic stimulation could potentially be beneficial.
Gomez Ricoy Escobar Velez How can the open probability EEG-TMS SocietyForNeu...Juan Gomez
This abstract proposes a method for maximizing the open probability of ion channels and burst waveform using EEG-triggered sequences of transcranial electrical stimulation (TES) and transcranial magnetic stimulation (TMS). The method aims to selectively amplify ongoing physiological processes like calcium influx and bursting through resonance with the natural frequencies of ion channel complexes. A short initial TES could induce more calcium influx from outside the cell, followed immediately by TMS to stimulate intracellular calcium flux toward vesicles. Thermal stimulation could help determine optimal noise levels and resonance frequencies. This "friendly" stimulation approach may help amplify natural healing processes in the heart or muscle contraction.
Gomez-Ricoy-Velez-Sepulveda Poster SfN2015 Ca TMS-TES ADJuan Gomez
This document summarizes a study investigating the use of EEG-triggered transcranial electric stimulation (TES) or transcranial magnetic stimulation (TMS) to modulate calcium signaling in Alzheimer's disease. Computer models suggest that TES/TMS can modify the amplitude and speed of calcium diffusion in neuronal columns. The study hypothesizes that TES/TMS could increase calcium amplitude and speed in columns with abnormal states to better match global EEG patterns, potentially improving function. Experimental validation is still needed to test effects on calcium homeostasis and avoid potential damage.
Gomez_Molina Restrepo-V Botero=P Field Generated by Waves Downloaded Jul 15 ...Juan Gomez
This document summarizes a study that used computer simulations to model the extracellular field (EF) generated by waves of neural activation. Specifically, it modeled:
1) Bilateral waves, where subregions could be in an activated, resting, or inhibited state. This produced biphasic, Gaussian, and Mexican hat waveforms.
2) Stochastic propagation waves, where activation spread randomly along a moving wavefront.
The simulations showed that bipolar recordings of EF are affected by the distance and movement of the wave relative to the electrodes. Distorted waves may cause pathologies, and modulating waves with electric or magnetic stimulation could potentially be beneficial.
Gomez Ricoy Escobar Velez How can the open probability EEG-TMS SocietyForNeu...Juan Gomez
This abstract proposes a method for maximizing the open probability of ion channels and burst waveform using EEG-triggered sequences of transcranial electrical stimulation (TES) and transcranial magnetic stimulation (TMS). The method aims to selectively amplify ongoing physiological processes like calcium influx and bursting through resonance with the natural frequencies of ion channel complexes. A short initial TES could induce more calcium influx from outside the cell, followed immediately by TMS to stimulate intracellular calcium flux toward vesicles. Thermal stimulation could help determine optimal noise levels and resonance frequencies. This "friendly" stimulation approach may help amplify natural healing processes in the heart or muscle contraction.