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CELLULAR
RESPIRATION
OVERVIEW OF CELLULAR RESPIRATION
A process that converts glucose into ATP
using oxygen.
Stages: Glycolysis Krebs Cycle
→ →
Electron Transport Chain (ETC)
Role of Oxygen in Aerobic
Respiration
◦Function: Oxygen is the final electron acceptor
in the ETC.
◦Combines with electrons and H⁺ to form water.
◦Maintains electron flow and proton gradient for
ATP synthesis.
ATP Yield in Aerobic Respiration
Glycolysis: 2 ATP
Krebs Cycle: 2 ATP
ETC: 34 ATP
Total: 38 ATP per glucose
What Happens Without Oxygen?
◦ETC stops NADH and FADH₂ cannot
→
donate electrons.
◦No proton gradient no ATP from ETC.
→
◦Cells switch to anaerobic pathways to
survive.
Anaerobic Pathways –
Fermentation
 Lactic Acid Fermentation:
o Occurs in muscle cells.
o Pyruvate Lactic acid + NAD⁺
→
 Alcoholic Fermentation:
o Occurs in yeast.
o Pyruvate Ethanol + CO₂ + NAD⁺
→
 Purpose: Regenerate NAD⁺ for glycolysis.
ATP Yield in Anaerobic Respiration
Glycolysis: 2 ATP
No Krebs or ETC
◦Total: 2 ATP per glucose (much less
efficient)
Why is oxygen essential for
maximizing ATP production
in cellular respiration?
How does the ability to adapt
energy pathways reflect the
resilience and stewardship built
into living systems?