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D-PHARM
2nd
YEAR
Presented by
Pragati K. Mahajan
1. Define Carbohydrates .
2. Classify Carbohydrates.
3. Draw the structure of various
carbohydrates.
Pragati K. Mahajan
Definition
• Carbohydrates may be defined as polyhydroxy aldehydes or ketones or
the compounds which produce them on hydrolysis.
• Carbohydrates are essential biomolecules consisting of carbon, hydrogen
&
oxygen & are known as hydrates of carbon.
Pragati K. Mahajan
Let’s understand definition
Compounds which produce them on hydrolysis
means:
Some carbohydrates do not directly contain an aldehyde or ketone
group, but when they are broken down by hydrolysis (reaction with
water), they produce simple sugars that do contain those groups.
Example Sucrose is a carbohydrate but does not have a free aldehyde
or ketone group.
When hydrolyzed, it breaks into:
Glucose (an aldehyde sugar)
Fructose (a ketone sugar)
Pragati K. Mahajan
Introduction
• These are the biomolecules or compound in which carbon, water
and oxygen are present in fixed ratio
• Carbohydrates are often called “saccharides” or described as
“saccharine” substances because many of them have a sweet taste.
• The word comes from the Latin word saccharum, which means
sugar.
C + H2O =1:2:1
Carbohydrates are most abundant organic molecules in the nature.
They Basically consists of
Pragati K. Mahajan
Pragati K. Mahajan
They are simply called as “ Hydrates of Carbon ” .
The most imp. Carbohydrate found in plant is
“Starch”
Where as in case of animals it is “ Glycogen
”
Pragati K. Mahajan
Their general formula is Cn (H2 o) n
Where n is number of carbon atoms
Ex. If number of carbon atoms Cn (H2 o) n
if n=1 then HCHO i.e. formaldehyde
if n=6 then C6H12O6 i.e. Glucose
Pragati K. Mahajan
Pragati K. Mahajan
Mono saccharides
(1 sugar unit)
These are simplest form of carbohydrates which are not
further
hydrolyzed into simpler units and therefore also called as “simple sugars” .
Their general formula is Cn(H2O)n
Where n is number of carbon atoms
Pragati K. Mahajan
Mono saccharides ( Only 1 unit)
They can be further divided by two ways based
on
a) Functional group b) No. of carbon atoms
a) Functional group
1) Aldoses : Aldehyde ( - CHO)
group
Ex. Glucose
2) Ketoses : Ketone (- C = o)
group
Ex. Fructose
Pragati K. Mahajan
b) No. of carbon atoms
No. of
carbon
Generic
name Aldoses Ketoses
3 Trioses
Aldotriose e.g.
glyceraldehyde
Ketotriose e.g.
Dihydroxyacetone
4 Tetroses
Aldotetrose e.g.
Erythrose
Ketotetrose e.g.
Erythrulose
5 Pentoses
Aldopentoses e.g
Arabinose, Xylose, Ribose
Ketopentoses e.g.
Xylulose, Ribulose
6 Hexoses
Aldohexose e.g. Glucose,
Galactose, Mannose Ketohexose e.g. Fructose
7 Heptoses
Aldoheptose:
Glucoheptose
Ketoheptose e.g
Sedoheptulose
Pragati K. Mahajan
Pragati K. Mahajan
Pragati K. Mahajan
Pragati K. Mahajan
Pragati K. Mahajan
Straight chain
Ring structure
D-Glucose
Pragati K. Mahajan
Pragati K. Mahajan
Pragati K. Mahajan
Pragati K. Mahajan
1. Identify chiral carbon or Asymmetric
carbon.
2. Classify Isomerism.
3. Determine the isomers of given carbohydrate
compound.
4. Describe the process of Mutarotation.
Pragati K. Mahajan
Pragati K. Mahajan
Structural isomerism
Definition : The compounds having Same molecular formulae but
differ from each other by having different structures.
Pragati K. Mahajan
Pragati K. Mahajan
Pragati K. Mahajan
Pragati K. Mahajan
1. Define Disaccharides.
2. Classify Disaccharides.
3. Draw the structure of Maltose, lactose, Sucrose.
Pragati K. Mahajan
Di saccharides
(2 sugar units)
Disaccharide consists of two monosaccharide units ( similar or dissimilar)
held together by a glycosidic hond.
Their basic formula is Cn (H2 o) n-1
Pragati K. Mahajan
Pragati K. Mahajan
Pragati K. Mahajan
 Maltose or malt sugar, is a disaccharide formed
from
two units of glucose.
Two molecules of glucose are linked
through  (1→4) glycosidic bond
Pragati K. Mahajan
Pragati K. Mahajan
⦿ Lactose is a disaccharide derived from the
condensation of galactose and glucose
⦿ Equimolar mixture of glucose and galactose is obtained
by hydrolysis of β (1→4) glycosidic bonds..
⦿ Like maltose, it also has reducing properties as it has
one aldehyde free.
Pragati K. Mahajan
Pragati K. Mahajan
Pragati K. Mahajan
To Be Continue…… Part 2