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Based on gene expression analysis, TLR8 (Toll like receptor 8) was identified as a potential drug
target. Well start by using the Human Protein Atlas (www.proteinatlas.org) to check the tissues
where TLR8 is expressed.
Search TLR8, and go to the Tissue page. In which tissue is TLR8 RNA expression highest?
In which tissues is TLR8 protein expression highest? What implications might this have on the
drug development process?
Using the information in the Pathology page: In which other cancer types is TLR8 protein
expressed?

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