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2012 11-08-3 d-printing-event-ceramics-medical

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2012 11-08-3 d-printing-event-ceramics-medical

  1. 1. Biomedical applications for Additive Manufacturing Additive Manufacturing for Ceramic parts ESMA – 8th of Novembre 2012 The Collective Centre of the Belgian Technology Industry le centre collectif de l’industrie technologique belge
  2. 2. Sirris AM&RP capacities - competencies • Laser sintering of polymeric powder (PA,…): P360 – P390 • Objet Connex 500: bi-material • Electron Beam Melting (Arcam A2) • Hybrid SLA system (Optoform) © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 2CENG
  3. 3. Custom medical implants, a necessity? Yes, it will work. But …. © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 3CENG
  4. 4. The utility of Additive Manufacturing technologies in the medical field Next generation pre-operative manufactured implants: • Custom implant manufacture : • CT-Scan • CAD File of the patient is produced • Engineer + Surgeon 3D implant approved • FEM analysis (when needed) • Custom manufacturing (low cost) • Surgery • Follow up [Sirris ADD] [Sirris ADD] [Sirris ADD] © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 4CENG
  5. 5. ADD capacities & competencies Medical Additive Manufacturing Software: • Materialise: Mimics • Materialise: 3matic • Marcam: Autofab • Able Software Corp: 3D Doctor • Medicim: Maxilim • ProEngineer • New: Lenexa: Analyze • New: Brisbane: Anatomics • (…) [Mimics & 3-matic - Materialise] © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 5CENG
  6. 6. The utility of Rapid Prototyping / Manufacturing in the medical field Trends in biocompatible materials used in Rapid Prototyping / Manufacturing: Metals: Polymers: • Titanium (Ti6Al4V) • PTFE (Polytetrafluoroethylene) • Ti-alloys • PMMA (Polymethyl methaacrylate) • Stainless steel • PE (Polyethylene) • Shape memory alloys (Ni-Ti) – in research • PEEK • Noble materials (Gold) • PEKK • … • … others, too but not implantable Ceramics: • Hydroxyapatite (HAP) Others: • Zirconia • Hydrogels + Human cells • Tricalcium phosphate (TCP) • Alumine • … © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 6CENG
  7. 7. The utility of Rapid Prototyping / Manufacturing in the medical field Leading applications: • Pre-surgical planning: [Arcam & Objet technology] • Custom implant manufacture • Physician to physician communication [Z. Corp Medical Modeling Solutions] • Powerful patient presentation tool • Medical student/resident education • 3D Surface Scanning/Custom Prosthesis Design • Patient-custom surgical guides (cutting & placement) [Sirris ADD] [Z. Corp Medical Modeling Solutions] © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 7CENG
  8. 8. The utility of Rapid Prototyping / Manufacturing in the medical field Leading applications: “No matter how good our 3-D graphics are, there is nothing like a model in your hands . . .” • Pre-surgical planning: • Implant pre-contouring • Screw trajectory • Screw selection/location • Instrument selection • Technique rehearsal • Surgical guides testing [Objet] [Objet] [Sirris ADD] [Objet] © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 8CENG
  9. 9. The utility of Rapid Prototyping / Manufacturing in the medical field Leading applications: • Pre-surgical planning advantages: • Significantly reduces O.R. time • Lowers cost • Reduces O.R. team fatigue • Enhances patient outcomes • Reduces “re-do” procedures • Minimizes size of incisions [Z. Corp Medical Modeling Solutions] • Speeds recovery time • Improves anatomical alignment • Enables multiple procedure rehearsals [Case study: The Alfred Hospital, Melbourne, Australia] © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 9CENG
  10. 10. Medical Field: Application fields Leading applications: • Physician to physician communication • Powerful patient presentation tool • Medical student/resident education • Custom Prosthesis Design • Complex parts manufacturing [Sirris ADD] [Sirris ADD] [Sirris ADD] [Sirris ADD] [Sirris ADD] [Sirris ADD] © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 10CENG
  11. 11. Medical Field: CASE STUDIES @ SIRRIS [Sirris ADD] [Sirris ADD] 0,5mm [Sirris ADD] [Sirris ADD] [Sirris ADD] © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 11CENG
  12. 12. Medical Field: CASE STUDIES in the world [Walter Reed Army Medical Center, Washington DC, USA ] [Dr J. Poukens - UHasselt] © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 12CENG
  13. 13. Medical Field: CASE STUDIES in the world © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 13CENG
  14. 14. World’s first total mandible implant in Titanium [UHasselt, Layerwise, Xilloc, Sirris, CamBioceramics, Orbis Medisch Centrum, Xios, KUL] © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 14CENG
  15. 15. World’s first total mandible implant in Titanium Inferior alveolar Lingual Hypoglossal [UHasselt, Layerwise, Xilloc, Sirris, CamBioceramics, Orbis Medisch Centrum, Xios, KUL] © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 15CENG
  16. 16. Towards newly designed implants [Butscher A., et al., Structural and material approaches to bone tissue engineering in powder-based three-dimensional printing. Acta Biomater (2010)] © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 16CENG
  17. 17. Towards newly designed implants Ti6Al4V: E(GPa) = 110 ! © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 17CENG
  18. 18. Towards newly designed implants Case study: Femoral & Total hip implants • Tomorrow: Custom-fit femoral implants & adapted Young’s modulus • Patient custom-fit implants • Better distribution of the stresses • Reducing stress-shielding • Reducing micro-motion between bone & sinkage • Surface roughness for strong fixation • Hydroxyapatite coating eased up • Complex biodegradable scaffolds combining HAP & βTCP + + [Sirris - ADD] [Sirris - ADD] © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 18CENG
  19. 19. The future of bio-manufacturing…not so far away! © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 19CENG
  20. 20. Additive Manufacturing: Organ printing [Karolinska Institute in Stockholm ] [Wake Forest University School of Medicine] [Wake Forest University School of Medicine] [Wake Forest University School of Medicine] [Wake Forest University School of Medicine] [University of Manchester - UK] © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 20CENG
  21. 21. « Medical Additive Manufacturing & Rapid Prototyping » « Sirris » © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 21CENG
  22. 22. Sirris Additive Manufacturing: Contact Carsten ENGEL Biomedical Engineer Department of Additive Manufacturing Mail: carsten.engel@sirris.be Mobile: +32 498 91 94 50 Skype: Carsten-Engel SIRRIS Rue Auguste Piccard, 20 B-6041 GOSSELIES BELGIUM http://www.sirris.be © sirris 2012 Charleroi | www.sirris.be | info@sirris.be | 15/11/2012 22CENG

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