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CV

  1. 1. UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE CURRICULUM VITAE September 2004 MARIELL L. JESSUP, M.D. (Formerly Mariell J. Likoff, M.D.) Home Address: 1101 Brynllawn Road Villanova, PA 19085 Office Address: Heart Failure/Transplant Ambulatory Care Center Hospital of the University of Pennsylvania 6 Penn Tower 3400 Spruce Street Philadelphia, PA 19104 Education: 9/68-6/72 B.S. University of Pennsylvania, (Biology) 9/72-6/76 M.D. Hahnemann Medical College Postgraduate Training and Fellowship Appointments: 6/76-6/77 Intern in Medicine, Hahnemann University Hospital Philadelphia, PA 6/77-6/79 Resident in Medicine, Hahnemann University Hospital, Philadelphia, PA 7/79-6/82 Fellowship, Cardiovascular Diseases, Hospital of the University of Pennsylvania, Philadelphia, PA Faculty Appointments 7/82-6/83 Research Associate, Department of Medicine University of Pennsylvania School of Medicine 7/83-5/86 Assistant Professor of Medicine, Department of Medicine Hahnemann University School of Medicine 6/85-5/86 Adjunct Assistant Professor, Department of Medicine Temple University School of Medicine 5/86-3/88 Assistant Professor of Medicine, Department of Medicine ,Temple University School of Medicine 3/88-6/90 Associate Professor of Medicine, Department of Medicine, Temple University School of Medicine 6/90-1/96 Clinical Associate Professor of Medicine, Department of Medicine, University of Pennsylvania School of Medicine 1/96-11/98 Professor of Medicine, Department of Medicine, MCP-Hahnemann School of Medicine, Allegheny University of the Health Sciences
  2. 2. Mariell L. Jessup, M.D 2 12/98-6/99 Lecturer C, Department of Medicine, University of Pennsylvania School of Medicine 7/99-9/03 Associate Professor of Medicine, Department of Medicine, University of Pennsylvania School of Medicine 9/03-present Professor of Medicine, Department of Medicine, University of Pennsylvania School of Medicine. Hospital and Administrative Appointments 6/83-5/86 Director, Heart Failure Unit, Likoff Cardiovascular Institute, Hahnemann University Hospital 5/86-6/90 Medical Director, Heart Failure and Transplantation Center, Temple University Hospital 6/90-1/96 Director, Heart Failure Unit & Cardiac Rehabilitation Center, Philadelphia Heart Institute, Presbyterian Medical Center 1/92-1/96 Director, Risk Reduction Center, Philadelphia Heart Institute, Presbyterian Medical Center 1/96-11/98 Director, Program Development, Center For Heart Failure and Transplantation, Allegheny Health, Education and Research Foundation 11/98-present Associate Director, Heart Failure/Transplant program, University of Pennsylvania Health System, Presbyterian Medical Center 11/98-present Director of Cardiovascular Medicine Special Projects, University of Pennsylvania Health System 11/98-present Associate Director, Penn Cardiac Care Outreach Program, University of Pennsylvania Health System. 11/00-6/02 Acting Medical Director, Heart Failure/Transplant program, University of Pennsylvania Health System, Hospital of the University of Pennsylvania 7/02-present Medical Director, Heart Failure/Transplant program, University of Pennsylvania Health System, Hospital of the University of Pennsylvania Specialty Certification: 9/79 American Board of Internal Medicine 11/81 American Board of Internal Medicine, Cardiovascular Licensure: Pennsylvania MD-020586-E Awards, Honors and Membership in Honorary Societies: 1976 J.M. Glasgow Award for Achievement American Medical Women’s Association 1980 Fellowship, Southeastern Pennsylvania American Heart Association 1981 Fellowship, Southeastern Pennsylvania American Heart Association
  3. 3. Mariell L. Jessup, M.D 3 2002 Distinguished Cardiovascular Division Teaching Award, HUP Memberships in Professional and Scientific Societies: National Societies: American College of Cardiology, Fellow 1983-present Annual Scientific Session Program Committee 1998-2000 Women in Cardiology Committee 1998-present American Medical Women’s Association, Member 1982-present International Society for Heart and Lung Transplantation Member 1992-present Co-Chairman, Heart Failure Council 1998-present Member, Program Committee 2001-present American Society of Transplant Physicians Member 1994-1998 American Heart Association Fellow, Council of Clinical Cardiology 1994-present Member, Program Committee for annual meeting 2000-present Heart Failure Society of America Member 1997-present Member, Heart Failure Awareness Committee 2000-present Member, Membership Committee 2000-2003 Local Societies: Philadelphia County Medical Society Member 1995-2000 Philadelphia College of Physicians Member 1989-2000 Pennsylvania Medical Society Member 2001-present Member, Commission on Women 2001-present National Scientific Committees: Transplant Cardiology Research Database Founding Member 1989-present AHCPR: Clinical Practice Guidelines; Heart Failure Committee member 1992-1994 American Board of Internal Medicine Cardiovascular Subspecialty Board Examination Committee , Committee member 1997-2003 National Coalition for Women with Heart Disease, Advisory Board American College of Cardiology representative 1999-present
  4. 4. Mariell L. Jessup, M.D 4 Society for Women’s Health Research, Advisory Board American College of Cardiology representative 1999-present American Board of Internal Medicine Continuing Professional Development: Chairman, Congestive Heart Failure Practice Improvement Module committee 2000-2002 ACC/AHA guidelines committee member Management of Congestive Heart Failure Guidelines 1999-2001; 2003-2004 ACGME Residency Review Committee for Internal Medicine Representative of ABIM 2002-present American Heart Association. Cardiovascular Science and Healthcare Disparities and the Minority Health Summit 2003. 2003 American College of Cardiology. Consensus Conference on Workforce. 2003 Editorial Positions: 1990-present Editorial Advisory Board, Heart Failure 1993-present Editorial Advisory Board, Journal of Cardiac Failure 1995-present Editorial Advisory Board, Journal of Heart and Lung Transplantation 1994 1994-present Editorial Advisory Board, Congestive Heart Failure 1995 1996-1998 Editorial Advisory Board, Futura Media Publications Reviewer 1996Circulation 1997New England Journal of Medicine 1998Journal of the American College of Cardiology Academic Committees: 1984.86 Medical Student Affairs Committee, Hahnemann University Hospital 1985.86 Committee for Human Studies, Temple University Hospital 1991.96 Research Committee, Philadelphia Heart Institute 1993.1997 Medical Records Committee, Presbyterian Medical Center 1996.98 Utilization Committee, Nazareth Hospital 2004.6 Committee on Appointments and Promotions, Department of Medicine, University of Pennsylvania 2004- Committee on Appointments and Promotions, School of Medicine, University of Pennsylvania Major Teaching and Clinical Responsibilities: 1. Attending rounds Heart Failure/Transplant service 3 months/year 2. Heart Failure Clinic 4 days/week 3. Transplant Clinic 3 days/week 4. CCU attending rounds 1 month/year. 11/98-6/2003 5. Cardiology Consult rounds 2 weeks/year. 11/98-6/2003
  5. 5. Mariell L. Jessup, M.D 5 Lectures by Invitation: (past five years only-selected) January 16-19, 1998 The New World of Cardiology. 1. “Transplantation: Who to refer and what to expect”. 2. Debate: “Non-transplant candidates with low ejection fractions should receive maximum treatment, including ICDs, to prevent sudden death”. Bahamas February 7, 1998 Cardiovascular Care and Clinical Trials 1997-1998. “Advanced heart failure 97-98: Evaluation, Transplantation, Devices”, Rush-Presbyterian University. Philadelphia, PA March 30, 1998 Annual Meeting, American College of Cardiology. “Arrhythmias in CHF”. Atlanta, GA April 1, 1998 Annual Meeting, American College of Cardiology. “The Patient with Advanced CHF”. Atlanta, GA May 21, 1998 “Mitral regurgitation in congestive cardiomyopathy: 1998 Superior University Course. Universita degli Studi di Milano. Milan, Italy September 21, 1998 Cardiologia 1998. 32nd Annual Congress. “Pathophysiology of mitral regurgitation in congestive cardiomyopathy”. “CHF and preserved left ventricular systolic function”. Milan, Italy. October 7, 1998 Cardiology Grand Rounds. “Advances in Heart Failure: Insights and Implications for Clinical Practice” Abington Hospital. Abington, PA October 10, 1998 Heart Failure Summit IV, Cleveland Clinic Foundation. “Point-Counterpoint: Randomized trials of long-term ventricular assist devices are mandatory” Cleveland, Ohio January 18, 1999. Symposium: The New World of Cardiology. 3 lectures: 1. "Alternatives to Transplantation,” 2. “Diastolic Dysfunction”, 3. A debate: ”All patients with NYHA Class III and IV CHF should be treated for ventricular arrhythmias to improve survival”. Bahamas February 27,1999. "VAD support from a cardiologist's perspective" A Thoratec VAD System Symposium. Philadelphia, PA March 7, 1999. American College of Cardiology annual meeting. Mini-Course moderator. “Progress in Nonpharmacologic Approaches to Heart Failure”. New Orleans, LA March 9, 1999. American College of Cardiology annual meeting. Evening Session. “Evaluation of the Cardiomyopathic Heart”. New Orleans, LA March 27,1999. Tri-State Society for Cardiovascular and Pulmonary Rehabilitation-Fifteenth Annual Symposium. “Heart Disease and Women-Can it be prevented?” Princeton, NJ May 5, 1999. “Cardiac Transplantation for the general internist”. Medical Grand Rounds, Fitzgerald- Mercy Hospital. Lansdowne, PA May 15, 1999. “Treatment of CHF-Diastolic Dysfunction” Medical Grand Rounds. Delaware County Memorial Hospital. Drexel Hill, PA June 15, 1999. “Atrial fibrillation and CHF: the link and treatment implications.” Universita Degli Studi di Milano. Corso Superiore di Terapia dell’Insufficienza Cardiaca. Milan, Italy September 16, 1999 23rd Annual Krembs Cardiac Teaching Day. Cardiology Y2K. “Update on evaluation and treatment of heart failure.” Binghamton, NY October 2, 1999 Heart Failure Summit V- a symposium sponsored by the Cleveland Clinic Foundation. “Heart failure due to diastolic dysfunction: A bird of a different color?” Cleveland, Ohio October 9, 1999 Current Problems in Cardiology-a symposium sponsored by Deborah Heart and Lung Center. “Newer issues in the management of congestive heart failure.” Browns Mills, NJ November 4, 1999 1999 Lifecare Conference. “Maximizing therapy for congestive heart failure.” Waterloo, NY
  6. 6. Mariell L. Jessup, M.D 6 November 8, 1999 American Heart Association annual meeting. “Diuretics in heart failure management.” Plenary Session Symposium: Heart Failure-Beyond Y2K. Atlanta, Georgia. November 9, 1999 American Heart Association annual meeting. Abstract session moderator. “Nonpharmacologic approaches to the treatment of heart failure”. Atlanta, Georgia. November 19-20, 1999New Trends in Congestive Heart Failure Treatment. “The congestive heart failure unit: organization of the care of the patient.” and “Debate: Transplant: Are there credible alternatives?”. Milan, Italy December 1, 1999 Managing Congestive Heart Failure for the New Millennium. “Introduction to the Disease: From myocyte to bedside.” and “Clinical Case Management Level I” Philadelphia, PA February 4, 2000 The New World of Cardiology annual symposium. “What a cardiologist must know to follow cardiac transplant patients”, “The management of the patient with congestive heart failure and ischemic mitral regurgitation”, “Debate: The patients with congestive cardiomyopathy in failure should be anticoagulated”. Bal Harbour, Florida. February 10, 2000 Cardiovascular disease for the primary care physician. “Diastolic heart failure” Chestnut Hill Hospital. Philadelphia, PA March 13, 2000 “Update on Transplantation: Who and when?” Symposium. American College of Cardiology annual meeting. Anaheim, CA March 15, 2000 “Cardiac function and heart failure”. Special session. American College of Cardiology annual meeting. Anaheim, CA March 15, 2000 “Mitral regurgitation and left ventricular dysfunction”. Luncheon panel. American College of Cardiology annual meeting. Anaheim, CA April 29, 2000 “Mitral regurgitation and left ventricular dysfunction.” Cardiology Grand Rounds. Hospital of the University of Pennsylvania. Philadelphia, PA November 9, 2000 “The Hot Questions in Heart Failure”. Cardiology Grand Rounds. UMDNJ-Robert Wood Johnson Medical School. New Brunswick, NJ. November 17, 2000 “The therapeutic integration of HF drugs: The first step in the prevention of sudden death”. Integration of Heart Failure Treatments. An International Symposium. Milan, Italy December 15, 2000 Heart Failure: Diagnosis and Treatment. International Congress. “Diagnosis of Heart Failure: Useful, Useless, and Necessary Examinations.” and “ Diuretics in heart failure: RALES and beyond.” Bolzano, Italy March 21, 2001 “Surgical Approaches to Heart Failure”. Luncheon Panel. American College of Cardiology annual meeting. Orlando, Florida. April 7, 2001 New Frontiers in Cardiology 2001. “Congestive heart failure: Current and new approaches to management.” Philadelphia, PA April 22, 2001 “Systolic versus diastolic dysfunction, differential diagnosis, initial testing” How to Provide the best care to heart failure patients. AHA/Futura symposium. St. Louis, Missouri May 10, 2001 “Advances with inotropes in treating congestive heart failure” Cardiology Grand Rounds. Royal Oak Beaumont Hospital, Royal Oak, Michigan May 12, 2001 “Medical Therapy for Heart Failure: Practice standards and impact on Mortality” Electrical therapy for heart failure. Chicago, Illinois May 25, 2001 “Diastolic heart failure” Geriatric Grand Rounds, University of Pennsylvania Institute of Aging. Philadelphia, Pennsylvania
  7. 7. Mariell L. Jessup, M.D 7 June 1, 2001 “CHF and Diastolic dysfunction: How should we be treating these patients while awaiting guidelines?” CardiAction Tututorial: Putting CHF and Risk management into practice. Indianapolis, Indiana June 4-6, 2001 “Systolic and diastolic dysfunction: Implications”; “Current pharmacologic approach to heart failure”; “Pharmacologic bridge to transplantation”. Heart Failure 2001: State of the Art. ACC Heart House Learning Center, Bethesda, Maryland September 11, 2001 “Gender: Extending the benefits of beta-blockade to patients across the heart failure spectrum” Heart Failure Society of America, annual meeting. Washington DC November 11, 2001 “Diastolic dysfunction: What is the evidence for practice?” Heart Failure: Progress and challenges in the new millenium. Symposium, American Heart Association, annual meeting. Anaheim , California January 30, 2002 “New trends in Heart Failure”. Cardiology Grand Rounds. Lankenau Medical Center. Wynnewood, Pennsylvania February 5, 2002 “New Trends in Heart Failure” Medical Grand Rounds. St. Luke’s Hospital. Bethlehem, Pennsylvania February 6, 2002 “Diastolic heart failure: Who gets it and what can be done?” Edna G. Kynett Memorial Foundation Lecture. Thomas Jefferson University. Philadelphia, Pennsylvania February 7, 2002 “Reviewing the evidence from large-scale mortality trials” Grand Rounds. Deborah Heart and Lung Center. Browns Mills, New Jersey February 22, 2002 “Diastolic heart failure in the elderly” Medical Grand Rounds. Chestnut Hill Hospital. Philadelphia, Pennsylvania March 19, 2002 “Who should get heart transplanted, and why?” Luncheon panel. American College of Cardiology, annual meeting. Atlanta, Georgia March 20, 2002 “Heart Failure in Women”. Symposium. American College of Cardiology, annual meeting. Atlanta, Georgia April 12, 2002 “Ischemic Heart Disease: Patient Selection”. Symposium. International Society of Heart and Lung Transplantation, annual meeting. Washington, DC April 27, 2002 “Cardiology” at Thalassemia Update: Current management and future therapies. CME conference sponsored by Cornell University Medical College. New York, New York May 8, 2002 “Economic impact of device therapy for heart failure-Pro/Con”. NASPE Expert Consensus Conference. NASPE’s 23rd Annual Scientific Session. San Diego, California May 24, 2002 “The new heart failure guidelines”. Medical Grand Rounds, St. Vincent’s Hospital. Toledo, Ohio. June 8, 2002 “The ACC/AHA Guidelines for heart failure”. Heart Failure Symposium. Concord, New Hampshire June 15, 2002 “2001 ACC/AHA Guidelines in the Management of Chronic Heart Failure” CME Symposium, University of Pennsylvania, Philadelphia, Pennsylvania July 19, 2002 “The ACC/AHA Guidelines in the management of chronic heart failure”. Cardiology Grand Rounds. St Francis Medical Center. Trenton, New Jersey September 17, 2002 “The new heart failure guidelines”. Paoli Hospital. Grand Rounds. Paoli, Pennsylvania September 24, 2002 “Overview of safety studies and randomized clinical trials.” Satellite Symposium. Heart Failure Society of America annual meeting. Boca Raton, Florida January 29, 2003 Visiting Professor. University of Minnesota. “The Dilemma of Severe Ischemic Cardiomyopathy”. Cardiology Grand Rounds. Minneapolis, Minnesota. February 6, 2003 “The ACC/AHA Guidelines in Heart Failure” Heart Failure Update. Lancaster General Hospital. Lancaster, Pennsylvania
  8. 8. Mariell L. Jessup, M.D 8 February 13, 2003 “The Dilemma of Severe Ischemic Cardiomyopathy” Cardiology Grand Rounds. Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania February 13, 2003 “What’s New in Heart Failure ?” Medical Grand Rounds. Community Medical Center. Toms River, New Jersey March 13, 2003 “Guideline Pathways: Evidence-Based management of heart failure.” Grand Rounds. Deborah Heart and Lung Center. Browns Mills, New Jersey March 30, 2003 “Medical Therapy for Heart Failure: Case-Based Approach”. Evening Session. Annual Scientific Session of the American College of Cardiology. Chicago, Illinois. March 31, 2003 “How to Set Up and Manage a Heart Failure Program” Annual Scientific Session of the American College of Cardiology, Chicago, Illinois. April 11, 2003 “Debate: Resynchronization therapy is an important advance in the management of congestive heart failure.” Evidence-Based Arrhythmia Management. Frankfurt, Germany April 12, 2003 “Debate: Resolved, Heart Transplantation has no future.” International Society for Heart and Lung Transplantation. Annual session. Vienna, Austria June 27, 2003 “Strategy in post-ischemic cardiomyopathy” VII Meeting on Heart Failure-International Symposium. Universita Degli Studi Di Siena. Siena, Italy August 2, 2003 “Overview: Medical Management of Heart Failure”. 16th Annual Dr. Walter M. Booker, Sr. Memorial Symposium. Association of Black Cardiologists. Philadelphia, Pennsylvania. September 29, 2003 “Important Pharmacologic Considerations” 11th Annual State-of-the-Art Arrhythmia Symposium. Univ. of PA. Philadelphia, PA November 21, 2003 “Women and Heart Disease: Profiles of risk and prevention.” Taking Charge: Women’s Health Issues across the Life Span. Capital Health System. Trenton, New Jersey. January 10, 2004 “The heart failure syndrome: Changing concepts and approaches.” Fourth Annual New Frontiers in Heart Failure Therapy. New York, New York. February 18, 2004 “Heart Failure Treatment” and “Evaluation and Management of Diastolic Dysfunction”. Cardiovascular Conference at Snowbird. Utah. April 2, 2004 “Endpoints for diagnostic devices.” Workshop: Key issues in endpoint selection and measurement for devices in heart failure. Washington D.C. April 28, 2004 “Cardiac Complications of Thalassemia. The 3rd Annual Thalassmeia Update: Current management and future therapies. Weill Medical College of Cornell University. San Francisco, California May 7, 2004 “Epidemiology, economics, and implications of heart failure.” Heart Failure CME Symposium. University of Pennsylvania. Philadelphia, Pennsylvania. May 19, 2004 “ What does heart failure therapy bring to the table?” Symposium: What to do after SCD- HeFT? The Heart Rhythm Society annual meeting. San Francisco, California June 2, 2004 “Hot topics in Heart Failure.” PENN CME: Best Practices in Collaborative Cardiovascular Care. Philadelphia, Pennsylvania. June 3, 2004 “A Heart Failure Conundrum: Models and Remodeling.” Cardiology Grand Rounds. Brigham and Women’s Hospital. Boston, Massachusetts August 27, 2004 “New medical therapies for peri-operative management of patients undergoing surgical procedures for heart failure.” Society of Thoracic Surgeons’ Heart Failure Management annual meeting. Louisville, Kentucky. September 13, 2004 “How to assess diastolic function in heart failure.” Heart Failure Society of America annual meeting. Toronto, Canada.
  9. 9. Mariell L. Jessup, M.D 9 September 14, 2004 “ICDs: Absolute indications, absolute contraindications.” Device therapy in heart failure. Symposium, Heart Failure Society of America annual meeting. Toronto, Canada. Organizing Roles in Scientific Meetings: April, 1997 International Society for Heart and Lung Transplantation, annual meeting. The heart failure symposium: Organizing Co-Chairman 1998.2000 American College of Cardiology, Annual Scientific Session, Program committee 2000-present American Heart Association, Council on Clinical Cardiology, Program Committee 2001-2003 International Society for Heart and Lung Transplantation, Annual Meeting, Program Committee 2001-2003 Heart Failure Society of America Heart Failure Awareness Committee Membership Committee 2004 Co-Director, University of Pennsylvania School of Medicine CME sponsored symposium. Heart Failure: Current practice and future frontiers. May 7, 2004. Bibliography: Research Publications, peer reviewed: 1. Victor MF, Likoff MJ, Mintz GS, Likoff W: Unstable angina pectoris of new onset. A prospective clinical and arteriographic study of 75 patients. American J Cardiol 47:228-32, 1981. 2. Macoviak JA, Stephenson LW, Spielman SR, Greenspan AM, Likoff MJ, St. John Sutton MG, Reichek N, Rachkind WJ, Edmunds LH: Replacement of ventricular myocardium with diaphragmatic skeletal muscle: Acute studies. J Thorac Cardiovasc Surg 81:519-27, 1981. 3. Likoff MJ, Reichek N, St. John Sutton MG, Macoviak JA, Harken AH: Epicardial mapping of segmental function: An echocardiographic method applicable in man. Circulation 66: 1050-8, 1982. 4. Weber KT, Likoff MJ, McCarthy DM: Low dose beta blockade in the treatment of chronic cardiac failure. Amer Heart J 104: 877-9, 1982. 5. Weber KT, Andrews V, Janicki JS, Likoff MJ, Reichek N: Pirbuterol, an oral beta adrenergic receptor agonist in the treatment of chronic cardiac failure. Circulation 66: 1262-7, 1982. 6. Likoff MJ, Weber KT, Andrew V, Janicki JS, St. John Sutton M, Wilson H, Rucci ML: Amrinone in the treatment of chronic cardiac failure. J Am Coll Cardiol 3: 1282-90, 1984. 7. Martin JL, Likoff MJ, Janicki JS, Laskey WK, Hirshfeld JW, Weber KT: Myocardial energetics and clinical response to the cardiotonic agent MDL 17,043 in advanced heart failure. J Am Coll Cardiol 4: 875-83, 1984.
  10. 10. Mariell L. Jessup, M.D 10 8. Likoff MJ, Weber KT, Andrews V, Janicki JS, Wilson H, Rocci ML. Milrinone in the treatment of chronic cardiac failure: A controlled trial. Amer Heart J 110: 1035-42, 1985. 9. Likoff MJ: Can patients with chronic congestive heart failure benefit from physical conditioning? A review of the potential adaptations to training. Heart Failure 1: 125-9, 1985. 10. Massie B, Bourassa M, DiBianco R, Hess M, Konstam M, Likoff M, Packer M. and Amrinone Multicenter Trial Group: Long-term oral administration of amrinone for congestive heart failure: Lack of efficacy of a multicenter controlled trial. Circulation 71: 963-71, 1985. 11. Janicki JS, Weber KT, Likoff MJ, Fishman AP: The pressure-flow response of the pulmonary circulation in patients with heart failure and pulmonary vascular disease. Circulation 72:1270-8, 1985. 12. Likoff MJ, Ulrich S, Hakki AH, Iskandrian AS: Comparison of acute hemodynamic response to dobutamine and intravenous MDL 17,043 (Enoximone) in severe congestive heart failure secondary to either ischemic cardiomyopathy or to idiopathic dilated cardiomyopathy. Am J Cardiol 57: 1328-34, 1986 13. Likoff MJ, St. John Sutton M, Weber KT, Janicki JS: The effect of chronic pulmonary hypertension on left ventricular size, function and interventricular septal motion. Am Heart J 113: 1114-22, 1987. 14. Likoff MJ, Hare TW, Gumbardo D, Chadwick B: An assessment of the response in oxygen uptake and exercise duration in patients with chronic cardiac failure. Heart Failure 2: 164-8, 1986. 15. Likoff MJ, Chandler SL, Kay HR: Clinical determinants of mortality in chronic congestive heart failure secondary to idiopathic dilated or to ischemic cardiomyopathy. Am J Cardiol 59: 634-8, 1987. 16. Jessup M, Scortichini D, Mintz G, Gutkowska J, Cantin M, LeJemtel T: Cardiac filling pressures and atrial natriuretic factor in patients with chronic heart failure. Heart Failure 2: 274, 1987. 17. Anderson JL, Baim DS, Fein SA, Goldstein RA, LeJemtel TH, Likoff MJ and Milrinone Investigators: Efficacy and safety of sustained (48 hour) intravenous infusions of milrinone in patients with severe congestive heart failure: A multicenter study. J Am Coll Cardiol 9: 711-22, 1987. 18. Jessup M, Spielman S, Hare T, Ulrich S, Samaha J: Lisinopril in the treatment of chronic cardiac failure: A controlled trial. Heart Failure 3: 114-7, 1987. 19. Jessup M, Ulrich S, Samaha J, Hefler D. Effects of low dose enoximone for chronic congestive heart failure. Am J Cardiol. 60(5):80C-84C, 1987. 20. Wilson H, Rocci MI Jr, Weber KT, Andrews V, Likoff MJ: Pharmacokinetics and hemodynamics of amrinone in patients with chronic cardiac failure of diverse etiology. Res Comm Chem Path & Pharm: 56(1):3-19, 1987. 21. Meissner MD, Wilson AR, Jessup M: Renal artery stenosis in heart failure. Am J. Cardiol 62: 1307-8, 1988.
  11. 11. Mariell L. Jessup, M.D 11 22. Gregor RJ, Chong CA, Augsburger JJ, Eagle RA, Carlson KM, Jessup M, Wong S, Naids R: Endogenous Nocardia Asteroides subretinal abscess diagnosed by transvitreal fine-needle aspiration biopsy. Retina 9: 118-21, 1989. 23. Schall RR, Petrucci RJ, Brozena SC, Cavarocchi NC, Jessup M: Cognitive function in patients with symptomatic dilated cardiomyopathy before and after cardiac transplantation. J Am Coll Cardiol 14: 1666-72, 1989. 24. Uretsky BF, Jessup M, Konstam MA, Dec GW, Leier CV, Benotti J, Murali S, Herrmann HC, Sandberg JD, For the Enoximone Multicenter Trial Group: Multicenter trial of oral enoximone in patients with moderate to moderately severe congestive heart failure: Lack of benefit compared with placebo. Circulation 82: 774-80, 1990. 25. Katz SD, Kubo SH, Jessup M, Brozena S, Troha JM, Walh J, Cohn JN, Sonnenblick EH, LeJemtel TH: A multicenter, randomized, double-blind, placebo-controlled trial of pimobendan, a new cardiotonic and vasodilator agent, in patients with severe congestive heart failure. Am Heart J 123:95-103, 1992. 26. Kubo SH, Gollub S, Bourge R, Rahko P, Cobb F, Jessup M, Brozena S, Brodsky M, Kirlin P, Shanes J, Konstam M, Gradman A, Morledge J, Cingvegrani M, Singh S, LeJemtel T, Nicklas J, Troha J, Cohn JN; for the Pimobendan Multicenter Research Group: Beneficial effects of pimobendan on exercise tolerance and quality of life in patients with heart failure. Results of a multicenter trial. Circulation 1992; 85:942-9. 27. Kao W, Jessup M. Exercise testing and exercise training in patients with congestive heart failure. J Heart and Lung Transplantation 1994, 13:5117-21. 28. Beller B, Bulle T, Bourge RC, Colfer H, Fowles RE, Giles TD, Grover J, Whipple JP, Fisher MB, Jessup M. Lisinopril versus placebo in the treatment of heart failure: The Lisinopril Heart Failure Study Group. J Clin Pharm. 35(7):673-80, 1995. 29. Furnary AP, Jessup M, Moreira LFP for the American Cardiomyoplasty Group: Multicenter trial of dynamic cardiomyoplasty for chronic heart failure. J Am Coll Cardiol 1996; 28:1175-80. 30. Rector TS, Benditt D, Chachques JC, Chiu RCJ, Delahaye F, Jessup M, Kirkorian G, Thiene G, Titus J for the Worldwide Cardiomyoplasty Group. Retrospective risk analysis for early heart-related death after cardiomyoplasty. J Heart Lung Transplant 1997; 16:1018-1025. 31. Goldstein S, Kennedy HL, Hall C, Anderson JL, Gheorghiade M, Gottlieb S, Jessup M, Karlsberg RP, Friday G, Haskell L. Metoprolol CR/XL in patients with heart failure: A pilot study examining the tolerability, safety, and effect on left ventricular ejection fraction. Am Heart J 1999; 138:1158-1165. 32. deDenus S, Al-Jazairi A, Loh E, Jessup M, Stanek EJ, Spinler SA. Dyslipemias and HMG-CoA Reductase inhibitor prescription in heart transplant recipients. Ann Pharmacother 2004; 38: 1-6.
  12. 12. Mariell L. Jessup, M.D 12 33. Brozena SC, Twomey C, Goldberg LR, Desai SS, Drachman B, Kao A, Popjes E, Zimmer R, Jessup M. A prospective study of continuous intravenous milrinone therapy for status IB patients awaiting heart transplant at home. J Heart Lung Transplant 2004;23:1082-86. Contributions to peer-reviewed clinical research publications, participation cited but not by authorship: 1. Captopril Multicenter Research Group: (Likoff, M., participating investigator, University of Pennsylvania clinical center). A Placebo Controlled Trial of Captopril in Refractory Chronic Congestive Heart Failure. J Am Coll Cardiol 2: 755-9, 1983. 2. DiBianco R, Shabetai R, Silverman BD, Leier CV, Benotti JR, with the Amrinone Multicenter Study Investigators: (Likoff, M., participating investigator, University of Pennsylvania clinical center) Oral amrinone for the treatment of chronic congestive heart failure: Results of a multicenter randomized double- blind and placebo-controlled withdrawal study. J Am Coll Cardiol 4: 855-60, 1984. 3. Captopril-Digoxin Multicenter Research Group: (Jessup, M., principal investigator, Temple University clinical center). Comparative effects of therapy with captopril and digoxin in patients with mild to moderate heart failure. JAMA 259: 539-43, 1988. 4. DiBianco R, Shabetai R, Kostuk W, Moran J, Schlant RC, Wright R for the Milrinone Multicenter Trial Group: (Jessup, M., principal investigator, Temple University clinical center). A comparison of oral milrinone, digoxin, and their combination in the treatment of patients with chronic heart failure. N Engl J Med 320: 677-81, 1989. 5. Packer M, Carver JR, Rodeheffer RJ, Ivanhoe RJ, DiBianco R, Zeldis SM, Hendrix GH, Bommer WJ, Elkayam U, Kukin ML For the PROMISE Study Research Group: (Jessup, M., principal investigator, Temple University clinical center). Effect of oral milrinone on mortality in severe chronic heart failure. N Engl J Med 1991; 325: 1468-75. 6. The SOLVD Investigators: (Jessup, M., principal investigator, Temple University clinical center). Effect of Enalapril on survival in patients with reduced left ventricular ejection fraction and congestive heart failure. N Engl J Med 1991; 325:293-302. 7. The SOLVD Investigators: (Jessup, M., principal investigator, Temple University clinical center). Effect of Enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. N Engl J Med 327:685-91, 1992. 8. Packer M, Narahara KA, Elkayam U, Sullivan JM, Pearle DL, Massie BM, Creager MA. (Jessup M., principal investigator, Presbyterian Medical Center clinical center). Double-blind, placebo-controlled study of the efficacy of flosequinan in patients with chronic heart failure. J Am Coll Cardiol 1993; 22:65-72. 9. Massie BM, Berk MR, Brozena SC, Elkayam U, Plehn JF, Kukin ML, Packer M, Murphy BE, Neuberg GW, and Steingart RM. (Jessup M., principal investigator, Presbyterian Medical Center clinical center). Can further benefit be achieved by adding flosequinan to patients with congestive heart failure who remain symptomatic on diuretic, digoxin and an angiotensin convertying enzyme inhibitor? Results of the Flosequinan – ACE inhibitor trial (FACET). Circulation 1993; 88:492-95.
  13. 13. Mariell L. Jessup, M.D 13 10. Feldman AM, Bristow MR, Parmley WW, Carson PE, Pepine CJ, Gilbert EM, Strobeck JE, Hendrix GH, Powers ER, Bain RP, White BG. For the Vesnarinone Study Group (Jessup M., principal investigator, Presbyterian Medical Center clinical center). Effects of Vesnarinone on morbidity and mortality in patients with heart failure. N Engl J Med 1993; 329:149-55. 11. Waagstein F, Bristow MR, Swedberg K, Camerinin F, Fowler MB, Silver MA, Gilbert EM, Johnson MR, Goss FG, Hjalmarson A for the Metotropolol in Dilated Cardiomyopathy (MDC) Trial Study Group: (Jessup M., principal investigator, Presbyterian Medical Center clinical center). Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy. Lancet 1993; 342: 1441-45. 12. Packer M, Gheorghiade M, Young J, Constantini PJ, Adams K, Cody RJ, Kent Smith L, Van Voorhees L, Gourley LA, King Jolly M, for the RADIANCE study: (Jessup, M, member of the Safety and Monitoring Committee). Withdrawal of digoxin from patients with chronic heart failure treated with angiotensin- converting-enzyme inhibitors. N Engl J Med 1993; 329:1-6. 13. CAPRIE steering committee: (Jessup M., prinicipal investigator, Presbyterian Medical Center clinical center). A Randomized, blinded, trial of clopidogrel versus aspirin in patients at risk of ischemic events, (CAPRIE). Lancet 1996; 348:1329-32. 14. Califf RM, Adams KF, McKenna WJ, Gheorghiade M, Uretsky BF, McNulty SE, Darius H, Schulman K, Zannad F, Handberg-Thurmond E,Harrell FE, Wheeler W, Soler-Soler J, Swedberg K, (Jessup, M, principal investigator, Presbyterian Medical Center clinical center). A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: The Flolan International Randomized Survival Trial (FIRST). Am Heart J 1997;134:44-49. 15. Cohn J, Goldstein SO, Greenberg BH,Lorell BH, Bourge RC, Jaski BE, Gottlieb SO, McGrew F, DeMets DL, White BG for the Vesnarinone Trial Investigators: (Jessup M, principal investigator, Medical College of Pennsylvania-Allegheny University Hospitals clinical center). A dose-dependent increase in mortality with Vesnarinone among patients with severe heart failure. N Engl J Med 1998; 339:1810-15. 16. Mann DL, McMurray JJV, Packer M, Swedberf K, Borer JS, Colucci WS, Dijan J, Drexler H, Feldman A, Kober L, Krum H, Liu P, Nieminem M, Tavazzi L, et al. (Jessup M, principal investigator for HUP clinical center). Targeted anticytokine therapy in patients with chronic heart failure. Circulation 2004;109:1594-1602. 17. Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, DeMarco T, Carson P, DiCarlo L, DeMets D, White BG, DeVries DW, Feldman AM for the COMPANION Investigators. (Jessup M, Co-Principal investigator for HUP clinical center).Cardiac-Resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med 2004;350:2140-50. Research publications, non peer-reviewed. 1. Macoviak JA, Stephenson LW, Spielman SR, Greensplan SR, Likoff MJ, St. John Sutton MG, Reichek N, Rashkind WJ, Edmunds LH: Enlargement of the right ventricle with a diaphragmatic autograft: Electrophysiologic and mechanical characteristics. Surgical Forum 31: 270-72, 1980.
  14. 14. Mariell L. Jessup, M.D 14 2. Macoviak JA, Likoff MJ, Reichek N, St. John Sutton MG, Wetstein L, Stephenson LW, Josephson ME, Moore EN, Harken AJ: Delineation of contractile heterogeneity by high frequency epicardial echo mapping in man. Surgical Forum 32: 242-44, 1981. 3. Weber KT, Janicki JS, Likoff MJ, Shroff SG, Andrews V: Chronic cardiac failure: Pathophysiologic and therapeutic considerations. Triangle 22: 1-7, 1983. 4. Likoff MJ, Weber KT, Andrews B, Janicki JS: Amrinone: A promising new cardiotonic agent in the treatment of chronic cardiac failure. Herz 8: 199-205, 1983. 5. Likoff MJ, Morganroth J: Clinical Perspectives in Cardiology: New Approaches to the management of congestive heart failure. Communications in Medicine, Vol. 2, No. 2, 1985. 6. Likoff MJ, Spielman SR: Mortality and the patient with chronic heart failure. Cardiovasc Rev Rep 6: 1306-10, 1985. 7. McClurken J, Cavarocchi NC, Kolff J, Jessup M, Barone C, Fingelton J, Balsara R, Dunn J: Therapeutic options in the management of mechanical complications with cardiogenic shock resulting from myocardial infarction. Transplantation Proceedings. 20: 788-93, 1988. 8. Schneider M, Cavarocchi N, Jessup M, McClurken J, Dunn J, Narins B, Balsara R, Viewig C, Kolff J: Azathioprine to reverse renal dysfunction after heart transplantation. Transplantation Proceedings. 20:795-99, 1988. 9. Jessup M, Cavarocchi N, Narins B, McClurken J, Kolff J: Antihypertensive therapy in patients following cardiac transplantation. A step-care approach. Transplantation Proceedings. 20: 801-6, 1988. 10. Badellino MM, Cavarocchi NC, Narins B, Jessup M, Alpern JB, McClurken JB, Shuman CR. Cardiac transplantation in diabetic patients. Transplantation Proceedings 22: 2384-8, 1990. 11. Jessup M: Cardiac transplantation, the role of the referring cardiologist. Cardiac Chronicle 4:1-5, 1990. 12. Jessup M: Commentary. Diabetes Spectrum 4:151-53, 1991. 13. Jessup M, Lakatta EG, Leier CV, Santinga JT: Managing CHF in the older patient. Patient Care 26:40-46, 1992. 14. Tecce MA, Jessup M: Beta-adrenergic blockade in patients with chronic heart failure: Issues and answers. Primary Cardiology 1994; 20-26:33. 15. Tecce MA, Jessup M. Partial left ventricular resection. ACC Current Journal Review 1998; March/April 52-53. Abstracts (past three years)
  15. 15. Mariell L. Jessup, M.D 15 1. Jha S, Kao A, Desai S, St. John Sutton M, Jessup M, Keating MT. Identification of a new locus of autosomal dominant dilated cardiomyopathy on chromosome 9q22-31. Circulation 2001; 104:II-135 2. Harding J, Piacentino V, Chambers S, Margulies K, Jessup M. Delayed repolarization after ventricular assist devcie support is associated with ventricualr arrythmias. J Cardiac Failure 2002; 8: S45. 3. Chalfoun NT, Jessup M, Ross HM, Kocovic DZ. Biventricular pacing in patients with chronic atrial fibrillation: Comparison to patients with normal sinus rhythm at 12 months. Journal of the American College of Cardiology 2003;41:89A. 4. Kao A, Allen MT, Jessup M. Do older heart transplant recipients have a normal quality of life? J of Heart Lung Transplant 2003; 22: S129 5. Harding J, Goldberg ML, O’Hara ML, Acker MA, Jessup M. Pre-operative predictors of outcome after VAD: can we predict survivors? J of Heart Lung Transplant 2003; 22: S205 6. Naidu SS, Chambers SV, Desai SS, Pini D, Jessup M. Does Hepatitis c (HCV) adversely affect outcome after heart transplantation? J Cardiac Failure 2003;9: S82 7. Brozena S, Twomey C, Goldberg L, Desai S, Drachman B, Kao A, Popjes, E, Zimmer R, Jessup M. A prospective study of out-patient continuous milrinone therapy in patients awaiting heart transplant. J Cardiac Failure 2003; 9:S62. 8. Kwon DH, Desai S, Jessup M, Kao A, Goldberg L. Nesiritide is effective for the treatment of decomensated heart failure. J Cardiac Failure 2003; 9:S112. 9. Horwitz PA, Epstein JA, Lepore JJ, Parmacek MS, Kao AC, Desai S, Goldberg LR, Jessup M, Cappola TP. Novel predictors of cardiac allograft rejection determined by peripheral blood gene expression. Circulation 2003; 108:IV-388. 10. Shah AM, Wiegers S, Brozena S, Desai S, Jessup M, Kao A, Goldberg L. Accuracy of hemodynamic measures by impedance cardiography in heart transplant patients. Journal of the American College of Cardiology 2004; 43: 194A. 11. Park SW, Kubo S, Jessup M, Bolling S, Acker M, Oh JK. Prevalence and mechanism of functional mitral regurgitation in dilated cardiomyopathy: Baseline data from the Acorn trials. Journal of the American College of Cardiology 2004; 43:220A. 12. Cappola T, Harsch M, Jessup M, Abraham WT, Young J,Petersen-Stejskal, St. John Sutton M. Men and women remodel differently in chronic systolic heart failure: Analyses from MIRACLE and MIRACLE- ICD. J Cardiac Failure 2004; 10:S25. 13. Elmariah S, Goldberg LR, Brozena S, Desai S, Jessup M, Allen MT, Kao A. Racial and gender differences in peak oxygen consumption in heart failure patients. J Cardiac Failure 2004; 10:S112.
  16. 16. Mariell L. Jessup, M.D 16 Editorials, reviews, chapters and reports from committees. 1. Weber KT, Janicki JS, Shroff SG, Likoff MJ, St. John Sutton MG: The right ventricle: Physiologic and pathophysiologic considerations. J Crit Care Med 11:323-8, 1983. 2. Weber KT, Janicki JS, Shroff SG, Likoff MJ: The cardiopulmonary unit: The body’s gas transport system. Clinics in Chest Medicine 4: 101-10, 1983. 3. Janicki JS, Weber KT, Likoff MJ, Fishman AP: Exercise testing to evaluate patient with pulmonary vascular disease. Am Rev Respir Dis 129: 593-5, 1984. 4. Weber KT, Wilson JR, Janicki JS, Likoff MJ: Exercise testing to evaluate patients with chronic cardiac failure. Amer Rev Resp Dis 129: 560-2, 1984. 5. Weber KT, Likoff MJ, Janicki JS, Andrews V: Advances in the evaluation and management of chronic cardiac failure. Chest 85: 253-259, 1984. 6. Weber KT, Likoff MJ, Janicki MJ: Exercise testing in the evaluation of cardiopulmonary disease: A cardiologist’s point of view. Clinics in Chest Medicine 5: 173-80, 1984. 7. Likoff MJ: Drugs for the management of congestive heart failure. Cardiovascular Drug Therapy. P. 153, 1986. Year Book Medical Publishers, Inc., Chicago. 8. Spielman SR, Likoff MJ, Kutalek SP: Prospective evaluation of ventricular arrhythmias using electrophysiologic techniques. Cardiology Clinics 4: 507-13, 1986. 9. Jessup M: The assessment of quality of life and exercise response in patients with chronic cardiac failure. Congestive Heart Failure, p. 39, 1987. Martinus Nijhoff Publishing. Boston. 10. Kolff J, Cavarocchi NC, Riebman JB, McClurken JB, Jessup M: The artificial heart: Design, capabilities and indications in the treatment of heart failure. Heart Failure 4:13-20, 1988. 11. Jessup, M: Managing congestive heart failure. Geriatrics 43: 35-9, 1988. 12. Jessup M, LeJemtel TH: Nondigitalis oral inotropic agents in dilated cardiomyopathy. Drug Therapy in Dilated Cardiomyopathy and Myocarditis. Marcel Dekker, Inc. New York, 1988, p. 167. 13. Jessup M: Angiotensin-Converting Enzyme Inhibitors: Are there significant clinical differences? J Am Coll Cardiol 13: 1248-50, 1989. 14. Jessup M, Brozena SC: Identification and management of potential heart transplant recipients. Cardiology Clinics 8: 11-21, 1990. 15. Brozena SC, Jessup M: Pathophysiologic strategies in the management of congestive heart failure. Annual Review of Medicine 41: 65-74, 1990.
  17. 17. Mariell L. Jessup, M.D 17 16. Rush JE, Jessup M: Drugs for heart failure. Early Phase Human Drug Evaluation. Macmillan Press Ltd., London 1990, p 313 17. Jessup M: Weaning from cardiopulmonary bypass. Theory and Practice. Chest 98:7-9, 1990. 18. Jessup M: Beta-adrenergic blockade in congestive heart failure: Answering the old questions. J Am Coll Cardiol 1991; 18: 1067-9. 19. Jessup M, Brozena SC: Cardiomyopathy and congestive heart failure. Current Management of Arrhythmias. BC Decker, Inc. Philadelphia 1991. 20. Jessup M: Cardiac output in heart failure. Cardiac output and regional flow in health and disase. Kluwer Academic Publishers. Dordrecht 1993. P 153. 21. Constanzo-Nordin MR, Cooper DKC, Jessup M, Renlund DG, Robinson JA, Rose EA. Task Force 6: Future Developments. From 24th Bethesda Conference: Cardiac Tranpslantation. J Am Coll Cardiol 1993; 22:54-64. 22. Walter JD, Jessup M. A review. Clinical Cardiac Rehabilitation: A Cardiologists Guide. Annals of Internal Medicine 1994; 120:350-52. 23. Konstam M, Dracup K, Baker D, Bottorff MB, Brooks NH, Dacey RA, Dunbar SB, Jackson AB, Jessup M, Johnson JC, Jones RH, Luchi RJ, Massie BM, Pitt B, Rose EA, Rubin LJ, Wright RF. Heart Failure: Evaluation and Care of Patients with Left-Ventricular Systolic Dysfunction. Clinical Practice Guidelines No. 11. AHCPR Publications No. 94-0612, 1995. 24. Konstam MA, Dracup K, Baker DW, Bottorff MB, Brooks NH, Dacey RA, Dunbar SB, Jackson AB, Jessup M, Johnson JC. Heart failure: evaluation and care of patients with left ventricular systolic dysfunction. J Card Failure. 1(2):183-7, 1995. 25. Jessup M, Gronda E. Editorial. A focus on Our Mission J Heart Lung Transplantation 1998; 17:333-4. 26. Jessup M, Manno CS. Diagnosis and Management of Iron-induced heart disease in Cooley’s Anemia. Cooley’s Anemia, Seventh Symposium. Annals of the New York Academy of Science vol. 850, 1998, p 242. 27. Jessup M. Chronic, refractory cardiac failure and ace-inhibitors: optimal dosage. Cura Intensiva Cardiologica 1997. Casa Editrice Scientifica Internazionale 1998. P 192. 28. Jessup M, Brozena S. New approaches in the management of patients with chronic congestive heart failure. Drugs of Today. 1999, 35(11): 849 29. Packer M, Cohn JN on behalf of the Steering Committee and Membership of the Advisory Council to improve outcomes nationwide in heart failure:(Jessup M, member of Advisory Council) Consensus Recommendations for the Management of Chronic Heart Failure. Am J Cardiol 1999;83:1A-38A.
  18. 18. Mariell L. Jessup, M.D 18 30. Tecce MA, Pennington JA, Segal BL, Jessup ML: Heart failure: clinical implications of systolic and diastolic dysfunction. Geriatrics. 54(8):24-8, 31-3, 1999. 31. Jessup M, Brozena SC: Treatment of advanced heart failure. Cardiology in Review 2000; 8:148-157. 32. Jessup M: Dynamic Cardiomyoplasty: Expectations and results. J Heart Lung Transplant 2000; 19:69-72. 33. Hsia HH, Jessup M, Marchlinski FE. Debate: Do all patients with heart failure require implantable defibrillators to prevent sudden death? Curr Control Trials Cardiovasc Med 2000;1:98-101 34. Jessup, M. Cardiac Function and Heart Failure [transcript]. 2000, American College of Cardiology Annual Scientific Session. http://www.acc.org/education/online/highlights/index.htm. 35. Jessup M. Mechanical cardiac-support devices: Dreams and devilish details. N Engl J Med. 2001; 345:1490-1493 36. Hunt SA, Baker DW, Chin MH, Cinquegrani MP, Feldman AM, Francis GS, Ganiats TG, Goldstein S, Gregoratos G, Jessup M, Noble RJ, Packer M, Silver MA, Stevenson LW. ACC/AHA Guidelines for the Evaluation and Management of Chronic Heart Failure in the Adult: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to revise the 1995 Guidelines for the evaluation and management of heart failure). American College of Cardiology Web site, 2001. 37. Hunt SA, Baker DW, Chin MH, Cinquegrani MP, Feldman AM, Francis GS, Ganiats TG, Goldstein S,Gregoratos G, Jessup M, Noble RJ, Packer M, Silver MA, Stevenson LW. ACC/AHA Guidelines for the Evaluation and Management of Chronic Heart Failure in the Adult: Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1995 Guidelines for the Evaluation and Management of Heart Failure): Developed in Collaboration With the International Society for Heart and Lung Transplantation; Endorsed by the Heart Failure Society of America. Circulation 2001;104:2996-3007. 38. Hunt SA, Baker DW, Chin MH, Cinquegrani MP, Feldman AM, Francis GS, Ganiats TG, Goldstein S, Gregoratos G, Jessup M, Noble RJ, Packer M, Silver MA, Stevenson LW, Gibbons RJ, Antman EM, Joseph S, Alpert JS, Faxon DP, Fuster V, Gregoratos G, Alice K. Loren AK, F. Hiratzka F, Richard O. Russell RO and Smith SC. ACC/AHA Guidelines for the Evaluation and Management of Chronic Heart Failure in the Adult: Executive Summary. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to revise the 1995 Guidelines for the Evaluation and Management of Heart Failure). Journal of the American College of Cardiology 2001;38:2101-13 39. Leier CV, Silver MA, Rich MW, Eichhorn EJ, Fowler MB, Giles TD, Johnstone DE, Le Jemtel TH, Lachmann JS, Levine TB, Armstrong PW, Dec WG, Jessup M, Howlett J, Hershberger RE, Cohn JN, Adams KF Jr, Colucci WS, Warner-Stevenson L, Hosenpud JD, Bristow MR, Pina I, Baughman KL, Binkley PF, Ventura HO, Francis GS, White M, Miller LW, Berry B, Missov E. Nuggets, pearls, and vignettes of master heart failure clinicians. (four parts) Congestive Heart Failure 2001-2002; pages 245, 297, 49.
  19. 19. Mariell L. Jessup, M.D 19 40. Manno CS, Jessup M. Hemoglobinopathies: an opportunity to study cardiac disease. Am J of Medicine 2001;111:407-408. 41. Cimato TR, Jessup M. Recipient selection in cardiac transplantation: Contraindications and risk factors for mortality. J Heart Lung Transplant 2002;21:1161-1173 42. Jessup M. Defining Heart Failure: Systolic versus diastolic dysfunction, differential diagnosis, initial testing. Heart Failure: Providing Optimal Care. Editors: Jessup M, McCauley KM. Futura, An imprint of Blackwell Publishing. Elmsford, New York. 2003 43. Jessup M. Understanding the syndrome of heart failure. A Clinician’s Guide to Heart Failure Management in the Ambulatory Setting. Humana Press. Totowa, New Jersey. 2003 43. Walsh MN, Jessup M. Diastolic dysfunction in women. Coronary Disease in Women:Evidence-Based Diagnosis and Treatment, Pages 93-101. Editors: Leslee J. Shaw and Rita F. Redberg. . Humana Press Totowa, New Jersey. 2003. 44. Jessup M. The less familiar face of heart failure. Journal of the American College of Cardiology. 2003; 41: 224-26. 45. Jessup M. Aldosterone blockade and heart failure. N Engl J Med. 2003; 348:1380-1382. 46. Jessup M, Brozena S. Heart Failure. N Engl J Med. 2003;348:2005-16. 47. Brozena SC, Jessup M. The new staging system for heart failure: What every primary care physician should know. Geriatrics 2003; 58(June) 31-36. 48. Jessup M, Brozena SC. Epilogue: Support devices for end stage heart failure. Ventricular Assist Devices and the Artificial Heart. Cardiology Clinics.2003; 21:135-139. 49. Jessup M. Resynchronization therapy is an important advance in the management of congestive heart failure:Antagonist. J Cardiovasc Electrophysiol 2003; 14:1-5. 50. Pierson RN, Barr ML, McCullough KP, Egan T, Garrity E, Jessup M, Murray S. Thoracic organ transplantation. American Journal of Transplantation 2004;4(Suppl.9): 93-105 51. Jessup M, Pina I. Is it important to examine gender differences in the epidemiology and outcome of severe heart failure? J Thorac Cardiovasc Surg 2004;127:1247-1252. 52. Warnes CA, Fedson SE, Foster E, Jessup M,Limacher MC, O’Donnell JA, Walsh MN. Working group 2: How to encourage more women to choose a career in cardiology. Journal of the American College of Cardiology 2004; 44:238-41. 53. Desai S, Jessup M. Epilogue. Practice Guidelines: role of internists and primary care physicians. Primary Prevention of Heart Failure. Medical Clinics of North America. 2004;88:1369-1380.
  20. 20. Mariell L. Jessup, M.D 20 Books 1. Heart Failure: Providing Optimal Care. Editors: Jessup M, McCauley KM. Futura, An imprint of Blackwell Publishing. Elmsford, New York. 2003 2. A Clinician’s Guide to Heart Failure Management in the Ambulatory Setting. Editors: Jessup M, Loh E. Humana Press. Totowa, New Jersey. 2003. Patents None
  21. 21. PAST GRANT SUPPORT NAME: Mariell L. Jessup, M.D. DEPARTMENT: Medicine/Cardiovascular DATE: November 2002 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Name of Grant Period of Grant Role in Grant** % Effort Funding Source Annual Additional Award Category* Direct Cost Comments*** 1. NONE _____________________________________________________________________________________________________________________ 2. _____________________________________________________________________________________________________________________ 3. ____________________________________________________________________________________________________________________ 4. _____________________________________________________________________________________________________________________ 5. 6. _____________________________________________________________________________________________________________________ 7. _____________________________________________________________________________________________________________________ *For Grant Category, use code in bold from the following menu: R01 NIH R01 CT Clinical Trials PP NIH Program Project, Center or Core Grants TG Training Grants FG Federal Grants - Other (including other individual NIH grants IG Industrial Grants (including pharmaceutical) and grants from VA, NSF, Dept. of Energy, etc.) PG Private Foundation Grants (including internal Penn grants) O Other
  22. 22. Mariell L. Jessup, M.D 22 CURRENT GRANT SUPPORT NAME: Mariell L. Jessup, M.D. DEPARTMENT: Medicine/Cardiovascular DATE November 2002 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Name of Grant Period of Grant Role in Grant** % Effort Funding Source Annual Additional Award Category* Direct Cost Comments*** 1. HCFA 9/20/00 - Multi-center trial/ Heart Failure Monitoring 9/19/04 FG PI 5% HCFA $867,279 Penn Coordinating Center _____________________________________________________________________________________________________________________ 2. COMPANION 5/11/00 - 4/30/04 IG PI 1% Guidant/CPI $121,606 Multi-center trial _____________________________________________________________________________________________________________________ 3. _____________________________________________________________________________________________________________________ 4. _____________________________________________________________________________________________________________________ 5. _____________________________________________________________________________________________________________________ 6. _____________________________________________________________________________________________________________________ 7. _____________________________________________________________________________________________________________________ *For Grant Category, use code in bold from the following menu: R01 NIH R01 CT Clinical Trials PP NIH Program Project, Center or Core Grants TG Training Grants FG Federal Grants - Other (including other individual NIH grants IG Industrial Grants (including pharmaceutical) and grants from VA, NSF, Dept. of Energy, etc.) PG Private Foundation Grants (including internal Penn grants) O Other
  23. 23. Mariell L. Jessup, M.D 23 PENDING GRANT SUPPORT NAME: Mariell L. Jessup, M.D. DEPARTMENT: Medicine/Cardiovascular DATE: November 2002 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Name of Grant Period of Grant Role in Grant** % Effort Funding Source Annual Additional Award Category* Direct Cost Comments*** 1. NONE _____________________________________________________________________________________________________________________ 2. _____________________________________________________________________________________________________________________ 3. _____________________________________________________________________________________________________________________ 4. _____________________________________________________________________________________________________________________ 5. 6. 7. *For Grant Category, use code in bold from the following menu: R01 NIH R01 CT Clinical Trials PP NIH Program Project, Center or Core Grants TG Training Grants FG Federal Grants - Other (including other individual NIH grants IG Industrial Grants (including pharmaceutical) and grants from VA, NSF, Dept. of Energy, etc.) PG Private Foundation Grants (including internal Penn grants) O Other
  24. 24. Mariell L. Jessup, M.D 24 Other Contributions to Clinical Research Name Mariell L. Jessup, M.D. Department Medicine/Cardiovascular Date November 2002 Name of Trial Sponsor Status Role Name of No. Patients Total N National PI Active/ Local P.I., and Affiliation Recruited of study Complete Patient recruiter by candidate Amrinone Clinical Trials Sterling Complete - 1984 PI ---- ---- --- Myocardial Energetics of MDL 17043 Merrill-Dow Complete - 1984 Co-PI ---- ---- --- Milrinone - Controlled Trial Sterling Complete - 1985 Co-PI ---- ---- --- Amrinone - Controlled Trial Sterling Complete - 1985 Local PI Packer, Massie ---- --- Milrinone Infusions Sterling Complete - 1987 Local PI ---- ---- --- Lisinopril - Controlled Trial Merck Complete - 1987 PI ---- ---- --- Enoximone Multi-center Trial Merrill-Dow Complete - 1989 Local PI Uretsky ---- --- Pimobendan Multi-center Trial ---- Complete - 1991 Local PI Cohn ---- --- Cardiomyoplasty Study Group Medtronic Complete - 1996 Local PI ---- ---- --- Pilot Metoprolol CR/XL Astra-Zeneca Complete - 1989 Local PI Goldstein ---- --- Captopril Multi-center Trial Squibb Complete - 1983 Local PI ---- ---- --- Captopril - Digoxin Multi-center Trial Squibb Complete - 1988 Local PI ---- ---- --- PROMISE Sterling Complete - 1991 Local PI Packer ---- --- SOLVD NIH Complete - 1992 Local PI Yusuf ---- --- Floseguinon Multi-Center Trial ---- Complete - 1993 Local PI Packer ---- --- FACET ---- Complete - 1993 Local PI Massie ---- --- Vesnarinone Study Group ---- Complete - 1993 Local PI Feldman ---- --- MDC Astra-Zeneca Complete - 1993 Local PI Waagstein ---- --- CAPRIE ---- Complete - 1996 Local PI ---- ---- --- FIRST ---- Complete - 1997 Local PI Califf ---- --- VEST ---- Complete - 1998 Local PI Cohn ---- ---

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