Biomedical Informatics Program

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Biomedical Informatics Program

  1. 1. University of Rochester Medical Center Clinical & Translational Science Institute Biomedical Informatics Program <ul><li>CTSA Steering Committee </li></ul><ul><li>December 7, 2006 </li></ul>Co-Directors: David Krusch, MD Hulin Wu, PhD Dongwen Wang, PhD
  2. 2. CTSA BIP Overview <ul><li>Biomedical Informatics Program </li></ul><ul><ul><li>Core resource for entire URMC research community </li></ul></ul><ul><ul><ul><li>Institutional Program / Department </li></ul></ul></ul><ul><ul><li>Facilitate communication </li></ul></ul><ul><ul><li>Sharing of data, knowledge </li></ul></ul><ul><ul><li>Advancing standards utilization (and understanding) </li></ul></ul><ul><ul><li>Center wide data warehousing and subject data management </li></ul></ul><ul><ul><li>Collaborative synthesis of URMC wide Clinical Informatics, Bioinformatics, and Experimental informatics disciplines </li></ul></ul>
  3. 3. URMC BIP Core Resources <ul><li>Administrative Structure </li></ul><ul><ul><li>Co-Directors </li></ul></ul><ul><ul><ul><li>David A. Krusch, MD </li></ul></ul></ul><ul><ul><ul><ul><li>Director Medical Informatics, CMIO Hospital Information Systems </li></ul></ul></ul></ul><ul><ul><ul><li>Dongwen Wang, PhD </li></ul></ul></ul><ul><ul><ul><ul><li>Biostatistics, Medical Informatics </li></ul></ul></ul></ul><ul><ul><ul><li>Hulin Wu, PhD </li></ul></ul></ul><ul><ul><ul><ul><li>Biostatistics, Bio-mathematical modeling, Biodefense immune modeling </li></ul></ul></ul></ul><ul><ul><li>Administrative Coordination </li></ul></ul><ul><ul><ul><li>Will DiGrazio, MS (GCRC Informatics Core Director) </li></ul></ul></ul><ul><li>Components </li></ul><ul><ul><li>GCRC Informatics Core </li></ul></ul><ul><ul><li>(Part of) Division of Medical Informatics </li></ul></ul><ul><ul><li>(Part of) Division of Biomedical Modeling and Bioinformatics </li></ul></ul>
  4. 4. CTSA BIP Organizational Structure
  5. 5. BIP Missions <ul><li>Service </li></ul><ul><ul><li>Facilitate communication </li></ul></ul><ul><ul><li>Provide routine consulting service to faculties and trainees </li></ul></ul><ul><ul><li>Coordinate use of existing informatics resources </li></ul></ul><ul><li>Research & development </li></ul><ul><ul><li>Assess information needs </li></ul></ul><ul><ul><li>Grow existing and create new informatics tools </li></ul></ul><ul><ul><li>Integrate and enhance informatics functions </li></ul></ul><ul><ul><li>Standard adoption and development </li></ul></ul><ul><ul><li>Grant writing </li></ul></ul><ul><li>Education </li></ul><ul><ul><li>Offer informatics courses, seminars, workshops, etc. </li></ul></ul><ul><ul><li>Develop informatics degree programs </li></ul></ul>
  6. 6. BIP Service Mission <ul><li>Facilitate communication </li></ul><ul><ul><li>Websites, email lists </li></ul></ul><ul><ul><li>News/events, new methodologies and technologies </li></ul></ul><ul><ul><li>Online information resources </li></ul></ul><ul><ul><li>Sharepoint system for internal communication, collaboration, and coordination </li></ul></ul><ul><li>Coordinate use of informatics resources </li></ul><ul><ul><li>Triage and referral </li></ul></ul><ul><li>Provide consulting services </li></ul><ul><ul><li>New investigators and trainees </li></ul></ul><ul><ul><li>Collaborative development </li></ul></ul><ul><li>Provide data management </li></ul><ul><ul><li>URMC wide clinical trials subject and data management – (eRT) [FDA 21CRF11 Compliant] </li></ul></ul><ul><ul><li>Consolidated data sharing services </li></ul></ul>
  7. 7. BIP Research & Development Mission <ul><li>Data and knowledge management </li></ul><ul><ul><li>Data management for clinical studies and lab experiments </li></ul></ul><ul><ul><li>Integration of different types of data from multiple sources </li></ul></ul><ul><ul><ul><li>Clinical data, experimental data, image data </li></ul></ul></ul><ul><ul><ul><li>Clinical / Translational Data Warehousing strategies </li></ul></ul></ul><ul><ul><ul><li>System wide clinical-translational data warehouse </li></ul></ul></ul><ul><li>Modeling and simulation </li></ul><ul><ul><li>Mathematical modeling / statistical inference </li></ul></ul><ul><ul><li>Better design of biomedical experiments and clinical studies </li></ul></ul><ul><ul><li>Better data interpretation </li></ul></ul><ul><li>Implementation of biomedical studies and clinical trials </li></ul><ul><ul><li>Develop / adopt tools for protocol management and study coordination </li></ul></ul><ul><ul><li>Examine URMC institute-wide web-based clinical trial subject and data management infrastructure </li></ul></ul>
  8. 8. BIP Research & Development Mission <ul><li>Develop infrastructure for informatics-mediated behavioral intervention </li></ul><ul><ul><li>Develop tools to facilitate subject recruitment and retention </li></ul></ul><ul><ul><li>Improve protocol compliance </li></ul></ul><ul><ul><li>Disseminate best practice </li></ul></ul><ul><ul><li>Mechanisms: online reminders, emails, phone-calls, paging, etc. </li></ul></ul><ul><ul><li>Targets: investigators, administrators / coordinators, clinicians, patients, etc. </li></ul></ul><ul><li>Integration of informatics services </li></ul><ul><ul><li>Data and knowledge management, modeling and simulation, clinical trial facilitation, behavioral intervention, regulation </li></ul></ul><ul><ul><li>Local information infrastructure </li></ul></ul><ul><li>Standard adoption / development for data and knowledge sharing </li></ul><ul><ul><li>Within and across institution </li></ul></ul>
  9. 9. BIP Education Mission <ul><li>Short-Term Plan </li></ul><ul><ul><li>Offer biomedical informatics courses </li></ul></ul><ul><ul><ul><li>BST 525 – Introduction to Health Informatics </li></ul></ul></ul><ul><ul><li>Seminars / workshops / tutorial series </li></ul></ul><ul><ul><ul><li>Educate all CTSA faculty and researchers in data management and research informatics topics </li></ul></ul></ul><ul><ul><li>Contribute to other training programs </li></ul></ul><ul><ul><ul><li>CTSA training section </li></ul></ul></ul><ul><ul><ul><li>Preventive cardiology training program </li></ul></ul></ul><ul><li>Long-Term Plan </li></ul><ul><ul><li>Develop a MS program in 2-3 years </li></ul></ul><ul><ul><li>Develop a PhD program in 5-7 years </li></ul></ul>
  10. 10. Interaction with Other CTSA Functions <ul><li>Backbone of communication </li></ul><ul><ul><li>Essentially interact with all other CTSA functions </li></ul></ul><ul><li>Examples </li></ul><ul><ul><li>Dissemination of information about new methodologies and technologies </li></ul></ul><ul><ul><li>CTSA wide protocol management tools </li></ul></ul><ul><ul><li>Community engagement </li></ul></ul><ul><ul><ul><li>Clinical trial subject recruitment and retention </li></ul></ul></ul><ul><ul><ul><li>Behavioral interventions targeted to patients </li></ul></ul></ul><ul><ul><li>Biostatistics </li></ul></ul><ul><ul><ul><li>Computational biology </li></ul></ul></ul><ul><ul><li>Training </li></ul></ul>
  11. 11. CTSA Steering Committee Efforts <ul><li>Consider common framework for intra and inter CTSA data sharing </li></ul><ul><li>Discuss opportunities for common clinical trials subject and data management </li></ul><ul><li>Define/identify uniform data repository and warehousing standards </li></ul><ul><li>Outline recommended architecture for elements of Biomedical Informatics Programs common to all CTSAs. </li></ul>

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